Matches in SemOpenAlex for { <https://semopenalex.org/work/W2021188687> ?p ?o ?g. }
- W2021188687 endingPage "558" @default.
- W2021188687 startingPage "552" @default.
- W2021188687 abstract "Mycobacterium tuberculosis (Mtb) infects about one-third of the world's population, with a majority of infected individuals exhibiting latent asymptomatic infection, while 5–10% of infected individuals progress to active pulmonary disease. Research in the past two decades has elucidated critical host immune mechanisms that mediate Mtb control. Among these, chemokines have been associated with numerous key processes that lead to Mtb containment, from recruitment of myeloid cells into the lung to activation of adaptive immunity, formation of protective granulomas and vaccine recall responses. However, imbalances in several key chemokine mediators can alter the delicate balance of cytokines and cellular responses that promote mycobacterial containment, instead precipitating terminal tissue destruction and spread of Mtb infection. In this review, we will describe recent insights in the involvement of chemokines in host responses to Mtb infection and Mtb containment (the good), chemokines contributing to inflammation during TB (the bad), and the role of chemokines in driving cavitation and lung pathology (the ugly)." @default.
- W2021188687 created "2016-06-24" @default.
- W2021188687 creator A5066883810 @default.
- W2021188687 creator A5083188118 @default.
- W2021188687 date "2014-12-01" @default.
- W2021188687 modified "2023-10-11" @default.
- W2021188687 title "Chemokines in tuberculosis: The good, the bad and the ugly" @default.
- W2021188687 cites W1581404300 @default.
- W2021188687 cites W1809211577 @default.
- W2021188687 cites W1837402067 @default.
- W2021188687 cites W1939948552 @default.
- W2021188687 cites W1942943435 @default.
- W2021188687 cites W1963506049 @default.
- W2021188687 cites W1964500804 @default.
- W2021188687 cites W1970318694 @default.
- W2021188687 cites W1987818432 @default.
- W2021188687 cites W1988451138 @default.
- W2021188687 cites W1990823840 @default.
- W2021188687 cites W1994803737 @default.
- W2021188687 cites W1999033863 @default.
- W2021188687 cites W2009021998 @default.
- W2021188687 cites W2009526264 @default.
- W2021188687 cites W2012421384 @default.
- W2021188687 cites W2014971932 @default.
- W2021188687 cites W2018292120 @default.
- W2021188687 cites W2019800021 @default.
- W2021188687 cites W2025157628 @default.
- W2021188687 cites W2026190085 @default.
- W2021188687 cites W2028385085 @default.
- W2021188687 cites W2036413236 @default.
- W2021188687 cites W2037497967 @default.
- W2021188687 cites W2047719515 @default.
- W2021188687 cites W2048009938 @default.
- W2021188687 cites W2052798492 @default.
- W2021188687 cites W2056539843 @default.
- W2021188687 cites W2057645972 @default.
- W2021188687 cites W2059359466 @default.
- W2021188687 cites W2060656064 @default.
- W2021188687 cites W2068589328 @default.
- W2021188687 cites W2069666375 @default.
- W2021188687 cites W2071723955 @default.
- W2021188687 cites W2080595107 @default.
- W2021188687 cites W2081325862 @default.
- W2021188687 cites W2082215285 @default.
- W2021188687 cites W2084338775 @default.
- W2021188687 cites W2084575557 @default.
- W2021188687 cites W2084655279 @default.
- W2021188687 cites W2084844837 @default.
- W2021188687 cites W2087621739 @default.
- W2021188687 cites W2091889982 @default.
- W2021188687 cites W2094735775 @default.
- W2021188687 cites W2094736478 @default.
- W2021188687 cites W2096145474 @default.
- W2021188687 cites W2098485516 @default.
- W2021188687 cites W2100990607 @default.
- W2021188687 cites W2104922237 @default.
- W2021188687 cites W2105446471 @default.
- W2021188687 cites W2105675616 @default.
- W2021188687 cites W2109543073 @default.
- W2021188687 cites W2111350904 @default.
- W2021188687 cites W2119264715 @default.
- W2021188687 cites W2119939752 @default.
- W2021188687 cites W2121499583 @default.
- W2021188687 cites W2123093300 @default.
- W2021188687 cites W2125686203 @default.
- W2021188687 cites W2125728863 @default.
- W2021188687 cites W2126744631 @default.
- W2021188687 cites W2126864422 @default.
- W2021188687 cites W2127513692 @default.
- W2021188687 cites W2130968927 @default.
- W2021188687 cites W2131436565 @default.
- W2021188687 cites W2132290892 @default.
- W2021188687 cites W2135375332 @default.
- W2021188687 cites W2136309048 @default.
- W2021188687 cites W2136501069 @default.
- W2021188687 cites W2136853977 @default.
- W2021188687 cites W2141361194 @default.
- W2021188687 cites W2144796452 @default.
- W2021188687 cites W2147896853 @default.
- W2021188687 cites W2151808188 @default.
- W2021188687 cites W2164394621 @default.
- W2021188687 cites W2164455824 @default.
- W2021188687 cites W2165184598 @default.
- W2021188687 cites W2166258374 @default.
- W2021188687 cites W2168456456 @default.
- W2021188687 cites W2169074220 @default.
- W2021188687 cites W2408829445 @default.
- W2021188687 cites W2464451761 @default.
- W2021188687 cites W4313422321 @default.
- W2021188687 cites W97158386 @default.
- W2021188687 doi "https://doi.org/10.1016/j.smim.2014.09.004" @default.
- W2021188687 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4314384" @default.
- W2021188687 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25444549" @default.
- W2021188687 hasPublicationYear "2014" @default.
- W2021188687 type Work @default.
- W2021188687 sameAs 2021188687 @default.
- W2021188687 citedByCount "78" @default.
- W2021188687 countsByYear W20211886872015 @default.