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• W2021242512 endingPage "S3" @default.
• W2021242512 startingPage "S3" @default.
• W2021242512 abstract "Deficits in central pain modulatory mechanisms, such as conditioned pain modulation (CPM) and enhanced suprathreshold heat pain response (SHPR), have been suggested to play a role in the development of post surgical pain. However, it remains unclear whether: a) central pain modulatory mechanisms change differentially in patients who improve from those that do not improve their level of pain intensity 6 months after shoulder surgery, and b) CPM and SHPR explain significant variability in post operative clinical pain after psychological factors (pain catastrophizing and depression) are considered. Seventy three patients with shoulder pain were examined before shoulder surgery, at 3 months, and 6 months after surgery. SHPR was generated with repeated thermal stimuli, and CPM was assessed using SHPR as the experimental stimulus and cold water bath as the conditioning stimulus. Patients were classified into improved (greater than 30% reduction in shoulder pain from baseline to 6 months after surgery)and not improved groups based on responses to Brief Pain Inventory (BPI) 6 months post-surgery. This study revealed that: 1) CPM, SHPR, and pain threshold did not differ at baseline in patients whose pain improved at 6 months compared to patients who did not improve, 2) Improved patients showed significant decreases in 5th pain rating of SHPR 3 months after surgery, however they did not change in CPM or pain threshold, 3) The change score of 5th pain rating of SHPR accounted for a significant amount of variance in 6 month post surgical pain intensity after psychological factors were considered. The results from the present study imply that baseline level of central pain modulation may not be a risk factor for continued pain at 6 months post surgery. However, plasticity of the central modulatory system may be a key factor in the transition to continued post operative pain. Funding: #AR055899 NIAMS/NIH. Deficits in central pain modulatory mechanisms, such as conditioned pain modulation (CPM) and enhanced suprathreshold heat pain response (SHPR), have been suggested to play a role in the development of post surgical pain. However, it remains unclear whether: a) central pain modulatory mechanisms change differentially in patients who improve from those that do not improve their level of pain intensity 6 months after shoulder surgery, and b) CPM and SHPR explain significant variability in post operative clinical pain after psychological factors (pain catastrophizing and depression) are considered. Seventy three patients with shoulder pain were examined before shoulder surgery, at 3 months, and 6 months after surgery. SHPR was generated with repeated thermal stimuli, and CPM was assessed using SHPR as the experimental stimulus and cold water bath as the conditioning stimulus. Patients were classified into improved (greater than 30% reduction in shoulder pain from baseline to 6 months after surgery)and not improved groups based on responses to Brief Pain Inventory (BPI) 6 months post-surgery. This study revealed that: 1) CPM, SHPR, and pain threshold did not differ at baseline in patients whose pain improved at 6 months compared to patients who did not improve, 2) Improved patients showed significant decreases in 5th pain rating of SHPR 3 months after surgery, however they did not change in CPM or pain threshold, 3) The change score of 5th pain rating of SHPR accounted for a significant amount of variance in 6 month post surgical pain intensity after psychological factors were considered. The results from the present study imply that baseline level of central pain modulation may not be a risk factor for continued pain at 6 months post surgery. However, plasticity of the central modulatory system may be a key factor in the transition to continued post operative pain. Funding: #AR055899 NIAMS/NIH." @default.
• W2021242512 created "2016-06-24" @default.
• W2021242512 creator A5019572514 @default.
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• W2021242512 date "2012-04-01" @default.
• W2021242512 modified "2023-09-23" @default.
• W2021242512 title "Investigation of central pain processing in post-operative shoulder pain" @default.
• W2021242512 cites W114083594 @default.
• W2021242512 cites W1211361266 @default.
• W2021242512 cites W144451483 @default.
• W2021242512 cites W1493010294 @default.
• W2021242512 cites W1500514965 @default.
• W2021242512 cites W1567412268 @default.
• W2021242512 cites W1931104708 @default.
• W2021242512 cites W1937307025 @default.
• W2021242512 cites W1958129788 @default.
• W2021242512 cites W1965066118 @default.
• W2021242512 cites W1966347718 @default.
• W2021242512 cites W1973545055 @default.
• W2021242512 cites W1975377094 @default.
• W2021242512 cites W1976926408 @default.
• W2021242512 cites W1978226111 @default.
• W2021242512 cites W1978245931 @default.
• W2021242512 cites W1978626885 @default.
• W2021242512 cites W1978896524 @default.
• W2021242512 cites W1978952533 @default.
• W2021242512 cites W1980721966 @default.
• W2021242512 cites W1982312202 @default.
• W2021242512 cites W1982884302 @default.
• W2021242512 cites W1982950630 @default.
• W2021242512 cites W1983322594 @default.
• W2021242512 cites W1984753997 @default.
• W2021242512 cites W1985239197 @default.
• W2021242512 cites W1986515235 @default.
• W2021242512 cites W1987232870 @default.
• W2021242512 cites W1988059170 @default.
• W2021242512 cites W1990682957 @default.
• W2021242512 cites W1991707775 @default.
• W2021242512 cites W1992707234 @default.
• W2021242512 cites W1993651959 @default.
• W2021242512 cites W1994463719 @default.
• W2021242512 cites W1994639499 @default.
• W2021242512 cites W1995166803 @default.
• W2021242512 cites W1995557364 @default.
• W2021242512 cites W1995992378 @default.
• W2021242512 cites W1996488784 @default.
• W2021242512 cites W1997184829 @default.
• W2021242512 cites W1997220477 @default.
• W2021242512 cites W1998044313 @default.
• W2021242512 cites W1999794762 @default.
• W2021242512 cites W2002542560 @default.
• W2021242512 cites W2002547721 @default.
• W2021242512 cites W2004407019 @default.
• W2021242512 cites W2006313441 @default.
• W2021242512 cites W2006601402 @default.
• W2021242512 cites W2007533243 @default.
• W2021242512 cites W2007848580 @default.
• W2021242512 cites W2009113851 @default.
• W2021242512 cites W2009877316 @default.
• W2021242512 cites W2010085055 @default.
• W2021242512 cites W2010829771 @default.
• W2021242512 cites W2011208019 @default.
• W2021242512 cites W2011268902 @default.
• W2021242512 cites W201567268 @default.
• W2021242512 cites W2016929710 @default.
• W2021242512 cites W2018174349 @default.
• W2021242512 cites W2019703818 @default.
• W2021242512 cites W2021602491 @default.
• W2021242512 cites W2025112709 @default.
• W2021242512 cites W2029042164 @default.
• W2021242512 cites W2029662381 @default.
• W2021242512 cites W2030849930 @default.
• W2021242512 cites W2031080375 @default.
• W2021242512 cites W2033358176 @default.
• W2021242512 cites W2036148606 @default.
• W2021242512 cites W2037723271 @default.
• W2021242512 cites W2038992813 @default.
• W2021242512 cites W2040574346 @default.
• W2021242512 cites W2041745363 @default.
• W2021242512 cites W2042052085 @default.
• W2021242512 cites W2042588834 @default.
• W2021242512 cites W2042887852 @default.
• W2021242512 cites W2044595147 @default.
• W2021242512 cites W2045448919 @default.
• W2021242512 cites W2046607147 @default.
• W2021242512 cites W2047196117 @default.
• W2021242512 cites W2048081411 @default.
• W2021242512 cites W2048203787 @default.
• W2021242512 cites W2048539973 @default.
• W2021242512 cites W2049841257 @default.
• W2021242512 cites W2050441598 @default.
• W2021242512 cites W2051590 @default.
• W2021242512 cites W2052930668 @default.
• W2021242512 cites W2053327083 @default.
• W2021242512 cites W2053803964 @default.

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