Matches in SemOpenAlex for { <https://semopenalex.org/work/W2021256283> ?p ?o ?g. }
- W2021256283 endingPage "65" @default.
- W2021256283 startingPage "60" @default.
- W2021256283 abstract "Alzheimer’s disease (AD) is one of the most significant neurodegenerative disorders in terms of both severity and cost. Despite being defined over a century ago, there is currently no cure to this disease that affects an increasing elderly population. The amyloid precursor protein (APP) has been shown to play an important role in AD progression. The amyloid β peptide (Aβ), which accumulates in senile plaques, a central etiological AD factor, is a proteolytic product from APP by the enzymatic action of β- and γ-secretases. In this review, we summarize the current knowledge of the processing and physiological functions of APP, and the involvement of APP and Aβ in AD." @default.
- W2021256283 created "2016-06-24" @default.
- W2021256283 creator A5012816933 @default.
- W2021256283 creator A5047680320 @default.
- W2021256283 creator A5069043938 @default.
- W2021256283 creator A5080357346 @default.
- W2021256283 date "2013-01-01" @default.
- W2021256283 modified "2023-10-16" @default.
- W2021256283 title "The role of APP in Alzheimer’s disease" @default.
- W2021256283 cites W1487900963 @default.
- W2021256283 cites W1602771322 @default.
- W2021256283 cites W1744830941 @default.
- W2021256283 cites W1821771945 @default.
- W2021256283 cites W1964049915 @default.
- W2021256283 cites W1968937229 @default.
- W2021256283 cites W1971855284 @default.
- W2021256283 cites W1972188808 @default.
- W2021256283 cites W1976444375 @default.
- W2021256283 cites W1988986946 @default.
- W2021256283 cites W1990752558 @default.
- W2021256283 cites W1994681896 @default.
- W2021256283 cites W1997822484 @default.
- W2021256283 cites W2003762128 @default.
- W2021256283 cites W2007093081 @default.
- W2021256283 cites W2010925911 @default.
- W2021256283 cites W2012921227 @default.
- W2021256283 cites W2017957082 @default.
- W2021256283 cites W2018354461 @default.
- W2021256283 cites W2020951538 @default.
- W2021256283 cites W2022060333 @default.
- W2021256283 cites W2022446410 @default.
- W2021256283 cites W2023463516 @default.
- W2021256283 cites W2024668515 @default.
- W2021256283 cites W2030892371 @default.
- W2021256283 cites W2032920422 @default.
- W2021256283 cites W2033891817 @default.
- W2021256283 cites W2036288989 @default.
- W2021256283 cites W2036809235 @default.
- W2021256283 cites W2040732053 @default.
- W2021256283 cites W2041581676 @default.
- W2021256283 cites W2041851050 @default.
- W2021256283 cites W2045089711 @default.
- W2021256283 cites W2045855955 @default.
- W2021256283 cites W2047217472 @default.
- W2021256283 cites W2048558199 @default.
- W2021256283 cites W2048621255 @default.
- W2021256283 cites W2054235701 @default.
- W2021256283 cites W2054542987 @default.
- W2021256283 cites W2056409809 @default.
- W2021256283 cites W2061650881 @default.
- W2021256283 cites W2064093411 @default.
- W2021256283 cites W2064470441 @default.
- W2021256283 cites W2064853825 @default.
- W2021256283 cites W2065384834 @default.
- W2021256283 cites W2067124006 @default.
- W2021256283 cites W2067415724 @default.
- W2021256283 cites W2069682857 @default.
- W2021256283 cites W2075638616 @default.
- W2021256283 cites W2081881251 @default.
- W2021256283 cites W2082022687 @default.
- W2021256283 cites W2086048645 @default.
- W2021256283 cites W2086234077 @default.
- W2021256283 cites W2088948837 @default.
- W2021256283 cites W2091505182 @default.
- W2021256283 cites W2104591424 @default.
- W2021256283 cites W2118012105 @default.
- W2021256283 cites W2121728123 @default.
- W2021256283 cites W2128111072 @default.
- W2021256283 cites W2130763296 @default.
- W2021256283 cites W2136125708 @default.
- W2021256283 cites W2143535578 @default.
- W2021256283 cites W2148568069 @default.
- W2021256283 cites W2152446053 @default.
- W2021256283 cites W2153966730 @default.
- W2021256283 cites W2155863144 @default.
- W2021256283 cites W2157359173 @default.
- W2021256283 doi "https://doi.org/10.4236/aad.2013.22008" @default.
- W2021256283 hasPublicationYear "2013" @default.
- W2021256283 type Work @default.
- W2021256283 sameAs 2021256283 @default.
- W2021256283 citedByCount "3" @default.
- W2021256283 countsByYear W20212562832014 @default.
- W2021256283 countsByYear W20212562832015 @default.
- W2021256283 countsByYear W20212562832020 @default.
- W2021256283 crossrefType "journal-article" @default.
- W2021256283 hasAuthorship W2021256283A5012816933 @default.
- W2021256283 hasAuthorship W2021256283A5047680320 @default.
- W2021256283 hasAuthorship W2021256283A5069043938 @default.
- W2021256283 hasAuthorship W2021256283A5080357346 @default.
- W2021256283 hasBestOaLocation W20212562831 @default.
- W2021256283 hasConcept C126322002 @default.
- W2021256283 hasConcept C142724271 @default.
- W2021256283 hasConcept C15744967 @default.
- W2021256283 hasConcept C169760540 @default.
- W2021256283 hasConcept C2777633098 @default.
- W2021256283 hasConcept C2779134260 @default.
- W2021256283 hasConcept C2908647359 @default.
- W2021256283 hasConcept C31705614 @default.