Matches in SemOpenAlex for { <https://semopenalex.org/work/W2021303620> ?p ?o ?g. }
- W2021303620 abstract "A unifying theme common to the action of many cationic peptides that display lethal activities against microbial pathogens is their specific action at microbial membranes that results in selective loss of ions and small nucleotides-chiefly ATP. One model cationic peptide that induces non-lytic release of ATP from the fungal pathogen Candida albicans is salivary histatin 5 (Hst 5). The major characteristic of Hst 5-induced ATP release is that it occurs rapidly while cells are still metabolically active and have polarized membranes, thus precluding cell lysis as the means of release of ATP. Other cationic peptides that induce selective release of ATP from target microbes are lactoferricin, human neutrophil defensins, bactenecin, and cathelicidin peptides. The role of released extracellular ATP induced by cationic peptides is not known, but localized increases in extracellular ATP concentration may serve to potentiate cell killing, facilitate further peptide uptake, or function as an additional signal to activate the host innate immune system at the site of infection." @default.
- W2021303620 created "2016-06-24" @default.
- W2021303620 creator A5023809168 @default.
- W2021303620 creator A5036961404 @default.
- W2021303620 creator A5082573256 @default.
- W2021303620 date "2007-02-08" @default.
- W2021303620 modified "2023-09-27" @default.
- W2021303620 title "The role of released ATP in killing Candida albicans and other extracellular microbial pathogens by cationic peptides" @default.
- W2021303620 cites W1531990967 @default.
- W2021303620 cites W1697103965 @default.
- W2021303620 cites W1814576137 @default.
- W2021303620 cites W1867012516 @default.
- W2021303620 cites W1901584600 @default.
- W2021303620 cites W1970743383 @default.
- W2021303620 cites W1977160855 @default.
- W2021303620 cites W1981424925 @default.
- W2021303620 cites W1981964308 @default.
- W2021303620 cites W1984706012 @default.
- W2021303620 cites W1989557252 @default.
- W2021303620 cites W1991526269 @default.
- W2021303620 cites W1992376704 @default.
- W2021303620 cites W1993280969 @default.
- W2021303620 cites W1996085928 @default.
- W2021303620 cites W1996174238 @default.
- W2021303620 cites W2000563070 @default.
- W2021303620 cites W2000714729 @default.
- W2021303620 cites W2006905725 @default.
- W2021303620 cites W2009440109 @default.
- W2021303620 cites W2010999630 @default.
- W2021303620 cites W2029302344 @default.
- W2021303620 cites W2029980168 @default.
- W2021303620 cites W2030299761 @default.
- W2021303620 cites W2031626398 @default.
- W2021303620 cites W2035420493 @default.
- W2021303620 cites W2039043665 @default.
- W2021303620 cites W2070762622 @default.
- W2021303620 cites W2075322040 @default.
- W2021303620 cites W2076519123 @default.
- W2021303620 cites W2077683600 @default.
- W2021303620 cites W2078277630 @default.
- W2021303620 cites W2084855906 @default.
- W2021303620 cites W2098875965 @default.
- W2021303620 cites W2101663202 @default.
- W2021303620 cites W2103188373 @default.
- W2021303620 cites W2103805019 @default.
- W2021303620 cites W2104559171 @default.
- W2021303620 cites W2110060823 @default.
- W2021303620 cites W2112222223 @default.
- W2021303620 cites W2112649783 @default.
- W2021303620 cites W2113602073 @default.
- W2021303620 cites W2116729426 @default.
- W2021303620 cites W2127310218 @default.
- W2021303620 cites W2129547737 @default.
- W2021303620 cites W2130714251 @default.
- W2021303620 cites W2138726430 @default.
- W2021303620 cites W2140678065 @default.
- W2021303620 cites W2140846341 @default.
- W2021303620 cites W2141676495 @default.
- W2021303620 cites W2147533168 @default.
- W2021303620 cites W2149168973 @default.
- W2021303620 cites W2159115385 @default.
- W2021303620 cites W2159326061 @default.
- W2021303620 cites W2160780417 @default.
- W2021303620 cites W2161180045 @default.
- W2021303620 cites W2170218469 @default.
- W2021303620 doi "https://doi.org/10.1007/s11302-006-9040-0" @default.
- W2021303620 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2096768" @default.
- W2021303620 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/18404422" @default.
- W2021303620 hasPublicationYear "2007" @default.
- W2021303620 type Work @default.
- W2021303620 sameAs 2021303620 @default.
- W2021303620 citedByCount "39" @default.
- W2021303620 countsByYear W20213036202012 @default.
- W2021303620 countsByYear W20213036202013 @default.
- W2021303620 countsByYear W20213036202014 @default.
- W2021303620 countsByYear W20213036202016 @default.
- W2021303620 countsByYear W20213036202017 @default.
- W2021303620 countsByYear W20213036202018 @default.
- W2021303620 countsByYear W20213036202019 @default.
- W2021303620 countsByYear W20213036202021 @default.
- W2021303620 countsByYear W20213036202022 @default.
- W2021303620 countsByYear W20213036202023 @default.
- W2021303620 crossrefType "journal-article" @default.
- W2021303620 hasAuthorship W2021303620A5023809168 @default.
- W2021303620 hasAuthorship W2021303620A5036961404 @default.
- W2021303620 hasAuthorship W2021303620A5082573256 @default.
- W2021303620 hasBestOaLocation W20213036201 @default.
- W2021303620 hasConcept C104317684 @default.
- W2021303620 hasConcept C136449434 @default.
- W2021303620 hasConcept C170493617 @default.
- W2021303620 hasConcept C185592680 @default.
- W2021303620 hasConcept C2777379352 @default.
- W2021303620 hasConcept C2779281246 @default.
- W2021303620 hasConcept C2780917455 @default.
- W2021303620 hasConcept C28406088 @default.
- W2021303620 hasConcept C512185932 @default.
- W2021303620 hasConcept C540938839 @default.
- W2021303620 hasConcept C55493867 @default.
- W2021303620 hasConcept C79879829 @default.
- W2021303620 hasConcept C86803240 @default.