Matches in SemOpenAlex for { <https://semopenalex.org/work/W2021332511> ?p ?o ?g. }
Showing items 1 to 99 of
99
with 100 items per page.
- W2021332511 endingPage "462" @default.
- W2021332511 startingPage "454" @default.
- W2021332511 abstract "Peripheral blood mononuclear cells from 20 previously untreated adult patients with Hodgkin's disease were evaluated for the ability to induce suppressor cell activity following in vitro exposure to concanavalin A (Con A). Suppression of proliferative responses by autologous as well as normal allogeneic peripheral blood lymphocytes to the mitogen phytohemagglutinin (PHA) was assessed using suppressor/responder cell ratios of 2:1 and 1:1. The generation of Con A-induced suppressor cell activity (T-T suppression) was deficient in 35% of the patients ( 7 20 ) by the criteria employed. Peripheral blood leukocytes from 18% of patients ( 2 11 ) with localized disease (stages I and II), and 56% of patients ( 5 9 ) with widespread disease (stages III and IV) exhibited subnormal suppressor activity. There was no correlation between absolute lymphocyte count, absolute T-cell number, or proliferative response to PHA, and Con A-induced suppressor cell activity. This impaired ability to generate Con A-induced suppressor cells in Hodgkin's disease may reflect a functional T-cell deficit, or the suppressive influence of abnormal circulating monocytes." @default.
- W2021332511 created "2016-06-24" @default.
- W2021332511 creator A5006117950 @default.
- W2021332511 creator A5008671765 @default.
- W2021332511 creator A5014561472 @default.
- W2021332511 creator A5025381409 @default.
- W2021332511 creator A5044440544 @default.
- W2021332511 creator A5058987519 @default.
- W2021332511 creator A5069781945 @default.
- W2021332511 date "1980-08-01" @default.
- W2021332511 modified "2023-10-17" @default.
- W2021332511 title "Concanavalin A-induced suppressor cell activity in Hodgkin's disease" @default.
- W2021332511 cites W1484912864 @default.
- W2021332511 cites W1494779975 @default.
- W2021332511 cites W1591495472 @default.
- W2021332511 cites W167117959 @default.
- W2021332511 cites W1911120442 @default.
- W2021332511 cites W1921500440 @default.
- W2021332511 cites W1979104920 @default.
- W2021332511 cites W1984067928 @default.
- W2021332511 cites W1995311633 @default.
- W2021332511 cites W2015514014 @default.
- W2021332511 cites W2024547328 @default.
- W2021332511 cites W2091519877 @default.
- W2021332511 cites W2120329687 @default.
- W2021332511 cites W2146741157 @default.
- W2021332511 cites W2329211716 @default.
- W2021332511 cites W2468119228 @default.
- W2021332511 cites W2469454152 @default.
- W2021332511 doi "https://doi.org/10.1016/0090-1229(80)90187-7" @default.
- W2021332511 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/6447556" @default.
- W2021332511 hasPublicationYear "1980" @default.
- W2021332511 type Work @default.
- W2021332511 sameAs 2021332511 @default.
- W2021332511 citedByCount "21" @default.
- W2021332511 crossrefType "journal-article" @default.
- W2021332511 hasAuthorship W2021332511A5006117950 @default.
- W2021332511 hasAuthorship W2021332511A5008671765 @default.
- W2021332511 hasAuthorship W2021332511A5014561472 @default.
- W2021332511 hasAuthorship W2021332511A5025381409 @default.
- W2021332511 hasAuthorship W2021332511A5044440544 @default.
- W2021332511 hasAuthorship W2021332511A5058987519 @default.
- W2021332511 hasAuthorship W2021332511A5069781945 @default.
- W2021332511 hasConcept C121608353 @default.
- W2021332511 hasConcept C126322002 @default.
- W2021332511 hasConcept C134018914 @default.
- W2021332511 hasConcept C137061746 @default.
- W2021332511 hasConcept C1491633281 @default.
- W2021332511 hasConcept C179185449 @default.
- W2021332511 hasConcept C19869320 @default.
- W2021332511 hasConcept C202751555 @default.
- W2021332511 hasConcept C203014093 @default.
- W2021332511 hasConcept C2776090121 @default.
- W2021332511 hasConcept C2777761686 @default.
- W2021332511 hasConcept C2779134260 @default.
- W2021332511 hasConcept C3017910909 @default.
- W2021332511 hasConcept C55493867 @default.
- W2021332511 hasConcept C71924100 @default.
- W2021332511 hasConcept C86803240 @default.
- W2021332511 hasConcept C8891405 @default.
- W2021332511 hasConceptScore W2021332511C121608353 @default.
- W2021332511 hasConceptScore W2021332511C126322002 @default.
- W2021332511 hasConceptScore W2021332511C134018914 @default.
- W2021332511 hasConceptScore W2021332511C137061746 @default.
- W2021332511 hasConceptScore W2021332511C1491633281 @default.
- W2021332511 hasConceptScore W2021332511C179185449 @default.
- W2021332511 hasConceptScore W2021332511C19869320 @default.
- W2021332511 hasConceptScore W2021332511C202751555 @default.
- W2021332511 hasConceptScore W2021332511C203014093 @default.
- W2021332511 hasConceptScore W2021332511C2776090121 @default.
- W2021332511 hasConceptScore W2021332511C2777761686 @default.
- W2021332511 hasConceptScore W2021332511C2779134260 @default.
- W2021332511 hasConceptScore W2021332511C3017910909 @default.
- W2021332511 hasConceptScore W2021332511C55493867 @default.
- W2021332511 hasConceptScore W2021332511C71924100 @default.
- W2021332511 hasConceptScore W2021332511C86803240 @default.
- W2021332511 hasConceptScore W2021332511C8891405 @default.
- W2021332511 hasIssue "4" @default.
- W2021332511 hasLocation W20213325111 @default.
- W2021332511 hasLocation W20213325112 @default.
- W2021332511 hasOpenAccess W2021332511 @default.
- W2021332511 hasPrimaryLocation W20213325111 @default.
- W2021332511 hasRelatedWork W1507483572 @default.
- W2021332511 hasRelatedWork W1512833508 @default.
- W2021332511 hasRelatedWork W2047755890 @default.
- W2021332511 hasRelatedWork W2058269113 @default.
- W2021332511 hasRelatedWork W2089845437 @default.
- W2021332511 hasRelatedWork W215531351 @default.
- W2021332511 hasRelatedWork W2408813421 @default.
- W2021332511 hasRelatedWork W2912051024 @default.
- W2021332511 hasRelatedWork W293089052 @default.
- W2021332511 hasRelatedWork W4290334697 @default.
- W2021332511 hasVolume "16" @default.
- W2021332511 isParatext "false" @default.
- W2021332511 isRetracted "false" @default.
- W2021332511 magId "2021332511" @default.
- W2021332511 workType "article" @default.