FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2021339649> ?p ?o ?g. }

• W2021339649 endingPage "602" @default.
• W2021339649 startingPage "598" @default.
• W2021339649 abstract "The aim of this study was to determine whether treatment with adipose-derived stem cells (ASCs) had any influence on fertility, course of pregnancy, newborn weight, or physical condition of newborns. We performed a retrospective study of patients with a desire to become pregnant after having received intralesional injection of autologous ASCs for the treatment of perianal or rectovaginal fistula associated with Crohn's disease. We collected data on the resulting pregnancies, deliveries, and newborns of these patients. ASCs were expanded in vitro and characterized according to the international guidelines for cell surface markers (clusters of differentiation) and differentiated to adipocytes, chondrocytes, and osteocytes prior to implantation (except first implant in 2002). We analyzed five young women with Crohn's disease treated with ASCs: one for rectovaginal and perianal fistula, two for rectovaginal fistula only, and two for perianal fistula only. All patients received 2 doses of 20 million and 40 million cells at an interval of 3-4 months. Another patient received 2 doses of 6.6 million and 20 million ASCs with 9 months between each dose. Fertility and pregnancy outcomes were not affected by cell therapy treatment. No signs of treatment-related malformations were observed in the neonates by their respective pediatricians. In the patients studied, cell therapy with ASCs did not affect the course of pregnancy or newborn development.Local treatment with mesenchymal stem cells derived from adipose tissue seems not to affect the ability to conceive, the course of pregnancy, pregnancy outcomes, or newborns' health in female patients. This is the first publication about pregnancy outcome in women with perianal fistula and Crohn's disease treated with stem cell therapy, and could be of interest for doctors working in cell therapy. This is a very important question for patients, and there was no answer for them until now." @default.
• W2021339649 created "2016-06-24" @default.
• W2021339649 creator A5014002954 @default.
• W2021339649 creator A5019660780 @default.
• W2021339649 creator A5037849031 @default.
• W2021339649 creator A5046202503 @default.
• W2021339649 creator A5051375079 @default.
• W2021339649 creator A5085111006 @default.
• W2021339649 date "2015-04-29" @default.
• W2021339649 modified "2023-10-18" @default.
• W2021339649 title "First-in-Human Case Study: Pregnancy in Women With Crohn's Perianal Fistula Treated With Adipose-Derived Stem Cells: A Safety Study" @default.
• W2021339649 cites W1497287788 @default.
• W2021339649 cites W1571521809 @default.
• W2021339649 cites W1971699289 @default.
• W2021339649 cites W1992298246 @default.
• W2021339649 cites W1995055794 @default.
• W2021339649 cites W1996662035 @default.
• W2021339649 cites W2009797297 @default.
• W2021339649 cites W2025371271 @default.
• W2021339649 cites W2041243709 @default.
• W2021339649 cites W2042820492 @default.
• W2021339649 cites W2043993755 @default.
• W2021339649 cites W2054918108 @default.
• W2021339649 cites W2067073937 @default.
• W2021339649 cites W2071487473 @default.
• W2021339649 cites W2083847109 @default.
• W2021339649 cites W2085016598 @default.
• W2021339649 cites W2085582924 @default.
• W2021339649 cites W2089301027 @default.
• W2021339649 cites W2093145539 @default.
• W2021339649 cites W2094061333 @default.
• W2021339649 cites W2097183141 @default.
• W2021339649 cites W2107714591 @default.
• W2021339649 cites W2107769242 @default.
• W2021339649 cites W2115062578 @default.
• W2021339649 cites W2118786877 @default.
• W2021339649 cites W2133426555 @default.
• W2021339649 cites W2136279247 @default.
• W2021339649 cites W2140399841 @default.
• W2021339649 cites W2145135012 @default.
• W2021339649 cites W2147785600 @default.
• W2021339649 cites W2151238232 @default.
• W2021339649 cites W2167320742 @default.
• W2021339649 cites W217193477 @default.
• W2021339649 cites W2173497140 @default.
• W2021339649 cites W2293494973 @default.
• W2021339649 cites W2414505431 @default.
• W2021339649 cites W2605187236 @default.
• W2021339649 doi "https://doi.org/10.5966/sctm.2014-0255" @default.
• W2021339649 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4449097" @default.
• W2021339649 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25925838" @default.
• W2021339649 hasPublicationYear "2015" @default.
• W2021339649 type Work @default.
• W2021339649 sameAs 2021339649 @default.
• W2021339649 citedByCount "31" @default.
• W2021339649 countsByYear W20213396492015 @default.
• W2021339649 countsByYear W20213396492016 @default.
• W2021339649 countsByYear W20213396492017 @default.
• W2021339649 countsByYear W20213396492018 @default.
• W2021339649 countsByYear W20213396492019 @default.
• W2021339649 countsByYear W20213396492020 @default.
• W2021339649 countsByYear W20213396492021 @default.
• W2021339649 countsByYear W20213396492022 @default.
• W2021339649 crossrefType "journal-article" @default.
• W2021339649 hasAuthorship W2021339649A5014002954 @default.
• W2021339649 hasAuthorship W2021339649A5019660780 @default.
• W2021339649 hasAuthorship W2021339649A5037849031 @default.
• W2021339649 hasAuthorship W2021339649A5046202503 @default.
• W2021339649 hasAuthorship W2021339649A5051375079 @default.
• W2021339649 hasAuthorship W2021339649A5085111006 @default.
• W2021339649 hasBestOaLocation W20213396491 @default.
• W2021339649 hasConcept C126322002 @default.
• W2021339649 hasConcept C131872663 @default.
• W2021339649 hasConcept C141071460 @default.
• W2021339649 hasConcept C142724271 @default.
• W2021339649 hasConcept C171089720 @default.
• W2021339649 hasConcept C198826908 @default.
• W2021339649 hasConcept C2776341189 @default.
• W2021339649 hasConcept C2779234561 @default.
• W2021339649 hasConcept C2779686005 @default.
• W2021339649 hasConcept C28328180 @default.
• W2021339649 hasConcept C54355233 @default.
• W2021339649 hasConcept C71924100 @default.
• W2021339649 hasConcept C86803240 @default.
• W2021339649 hasConceptScore W2021339649C126322002 @default.
• W2021339649 hasConceptScore W2021339649C131872663 @default.
• W2021339649 hasConceptScore W2021339649C141071460 @default.
• W2021339649 hasConceptScore W2021339649C142724271 @default.
• W2021339649 hasConceptScore W2021339649C171089720 @default.
• W2021339649 hasConceptScore W2021339649C198826908 @default.
• W2021339649 hasConceptScore W2021339649C2776341189 @default.
• W2021339649 hasConceptScore W2021339649C2779234561 @default.
• W2021339649 hasConceptScore W2021339649C2779686005 @default.
• W2021339649 hasConceptScore W2021339649C28328180 @default.
• W2021339649 hasConceptScore W2021339649C54355233 @default.
• W2021339649 hasConceptScore W2021339649C71924100 @default.
• W2021339649 hasConceptScore W2021339649C86803240 @default.
• W2021339649 hasFunder F4320313831 @default.

• next