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- W2021343463 abstract "We describe neuroblastoma (NB) in monozygotic twins whose ages at the onset of the disease had a 3-year interval. The primary tumor site of twin 1 was the adrenal gland, whereas that of twin 2 was the jejunum/mesentery. MYCN amplification, DNA index, ALK mutation, and copy number alterations of DNA were different between each primary tumor. NB in ectopic sites may have resulted from twin-to-twin metastasis through vascular anastamoses in the placenta. The pathogenesis of this NB involved a premalignant stage of NB during the fetal development and subsequent molecular alterations after birth, resulting in NBs that were phenotypically similar but genetically different." @default.
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- W2021343463 date "2014-03-01" @default.
- W2021343463 modified "2023-10-03" @default.
- W2021343463 title "Ectopic Neuroblastoma in Monozygotic Twins With Different Ages of Onset" @default.
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- W2021343463 doi "https://doi.org/10.1097/mph.0b013e318290c686" @default.
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