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- W2021387503 abstract "Abstract The extent of oxygen release from two heme proteins, haemoglobin and myoglobin have been studied in the presence of trifluoperazine and chlorpromazine (5–1000 μM). At a molar ratio (drug: protein) of 1.5, the release of oxygen from haemoglobin was 4 and 15% in the presence of chlorpromazine and trifluoperazine respectively, while from myoglobin the corresponding values were 20 and 40%. The findings were attributed to the greater extent of local conformational change around tryptophan moieties of each of the proteins induced by trifluoperazine." @default.
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- W2021387503 date "1996-09-01" @default.
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- W2021387503 title "Trifluoperazine is More Effective than Chlorpromazine in Releasing Oxygen from Haemoglobin and Myoglobin" @default.
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- W2021387503 doi "https://doi.org/10.1111/j.2042-7158.1996.tb06013.x" @default.
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