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• W2021420744 abstract "The eigenfunctions for circular boundary conditions of the differential equation first used by Harris and Hearst in 1966 to represent the dynamic properties of the wormlike coil have now been applied to the closed circular coils of high writhe. In order to avoid problems of knotting and excluded volume, the discussion here has been restricted to three-dimensional eigenfunctions with near plectonemic symmetry, i.e., eigenfunctions which cross each constant z plane only twice. It is concluded that at the natural levels of superhelical density that are found for DNA in vivo, the DNA free of protein must be in a highly reduced configurational entropy state. The impact of this conclusion on issues of entanglement, chromosome replication and segregation, and chromosome organization are discussed." @default.
• W2021420744 created "2016-06-24" @default.
• W2021420744 creator A5002908850 @default.
• W2021420744 creator A5062542148 @default.
• W2021420744 date "1991-12-15" @default.
• W2021420744 modified "2023-09-27" @default.
• W2021420744 title "Statistical mechanical theory for the plectonemic DNA supercoil" @default.
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• W2021420744 doi "https://doi.org/10.1063/1.461810" @default.
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