FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2021436699> ?p ?o ?g. }

• W2021436699 endingPage "470" @default.
• W2021436699 startingPage "462" @default.
• W2021436699 abstract "CXCL8 also called interleukin-8, is a CXC-type chemokine that plays a key role in promoting inflammation. Three subgroups of CXCL8 homologues have been reported in teleost fish, including CXCL8_L1, CXCL8_L2 and CXCL8_L3. In the present study, we identified a CXCL8 homologue belonging to CXCL8_L1 subgroup (LycCXCL8_L1) in large yellow croaker (Larimichthys crocea) that shares low identity to the previously reported large yellow croaker CXCL8 (LycCXCL8). The full-length cDNA of LycCXCL8_L1 is 716 nucleotides (nt) long and encodes a protein consisting of 99 amino acids (aa) with a putative molecular weight of 11.2 kDa. The deduced LycCXCL8_L1 protein contains a 22-aa signal peptide and a 77-aa mature polypeptide, which possesses an arrangement of four cysteines typical of other known CXC chemokines (C34, C36, C60, and C77). Genomic analysis revealed that the LycCXCL8_L1 gene consisted of four exons and three introns and exhibited a similar exon-intron organization to LycCXCL8 and other species CXCL8 genes except for a different intron length. Phylogenetic analysis showed that both LycCXCL8_L1 and LycCXCL8 belong to CXCL8_L1 subgroup. LycCXCL8_L1 mRNA was constitutively expressed in all tissues examined although at different levels. Upon bacterial vaccine induction, LycCXCL8_L1 mRNA expression was rapidly increased in the spleen and head kidney tissues. Recombinant LycCXCL8_L1 and LycCXCL8 proteins produced in Escherichia coli both induced chemotaxis and superoxide production in peripheral blood leucocytes from large yellow croaker. These results indicate that two CXCL8_L1 molecules exist in large yellow croaker and play roles in inflammatory response." @default.
• W2021436699 created "2016-06-24" @default.
• W2021436699 creator A5000006051 @default.
• W2021436699 creator A5012306799 @default.
• W2021436699 creator A5025283381 @default.
• W2021436699 creator A5040082665 @default.
• W2021436699 date "2015-06-01" @default.
• W2021436699 modified "2023-10-14" @default.
• W2021436699 title "Molecular characterization and biological effects of a CXCL8 homologue in large yellow croaker (Larimichthys crocea)" @default.
• W2021436699 cites W1898569975 @default.
• W2021436699 cites W1965295046 @default.
• W2021436699 cites W1967876529 @default.
• W2021436699 cites W1969904510 @default.
• W2021436699 cites W1969990928 @default.
• W2021436699 cites W1972853281 @default.
• W2021436699 cites W1973139773 @default.
• W2021436699 cites W1978706974 @default.
• W2021436699 cites W1980544070 @default.
• W2021436699 cites W1987312344 @default.
• W2021436699 cites W1989785466 @default.
• W2021436699 cites W1990775730 @default.
• W2021436699 cites W1996490932 @default.
• W2021436699 cites W1996539617 @default.
• W2021436699 cites W2007741751 @default.
• W2021436699 cites W2011465945 @default.
• W2021436699 cites W2011653766 @default.
• W2021436699 cites W2014587187 @default.
• W2021436699 cites W2020686859 @default.
• W2021436699 cites W2028374346 @default.
• W2021436699 cites W2033310634 @default.
• W2021436699 cites W2034826455 @default.
• W2021436699 cites W2036820299 @default.
• W2021436699 cites W2037372367 @default.
• W2021436699 cites W2041174434 @default.
• W2021436699 cites W2053033209 @default.
• W2021436699 cites W2053126973 @default.
• W2021436699 cites W2057877275 @default.
• W2021436699 cites W2060447390 @default.
• W2021436699 cites W2063034103 @default.
• W2021436699 cites W2067535806 @default.
• W2021436699 cites W2068385074 @default.
• W2021436699 cites W2069895301 @default.
• W2021436699 cites W2075785603 @default.
• W2021436699 cites W2077440788 @default.
• W2021436699 cites W2084375819 @default.
• W2021436699 cites W2091751352 @default.
• W2021436699 cites W2101372562 @default.
• W2021436699 cites W2102540234 @default.
• W2021436699 cites W2107277218 @default.
• W2021436699 cites W2142143111 @default.
• W2021436699 cites W2143372911 @default.
• W2021436699 cites W2152207030 @default.
• W2021436699 doi "https://doi.org/10.1016/j.fsi.2015.03.026" @default.
• W2021436699 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25827624" @default.
• W2021436699 hasPublicationYear "2015" @default.
• W2021436699 type Work @default.
• W2021436699 sameAs 2021436699 @default.
• W2021436699 citedByCount "28" @default.
• W2021436699 countsByYear W20214366992015 @default.
• W2021436699 countsByYear W20214366992016 @default.
• W2021436699 countsByYear W20214366992017 @default.
• W2021436699 countsByYear W20214366992018 @default.
• W2021436699 countsByYear W20214366992019 @default.
• W2021436699 countsByYear W20214366992020 @default.
• W2021436699 countsByYear W20214366992021 @default.
• W2021436699 countsByYear W20214366992023 @default.
• W2021436699 crossrefType "journal-article" @default.
• W2021436699 hasAuthorship W2021436699A5000006051 @default.
• W2021436699 hasAuthorship W2021436699A5012306799 @default.
• W2021436699 hasAuthorship W2021436699A5025283381 @default.
• W2021436699 hasAuthorship W2021436699A5040082665 @default.
• W2021436699 hasConcept C104317684 @default.
• W2021436699 hasConcept C10858879 @default.
• W2021436699 hasConcept C13373296 @default.
• W2021436699 hasConcept C153911025 @default.
• W2021436699 hasConcept C167625842 @default.
• W2021436699 hasConcept C170493617 @default.
• W2021436699 hasConcept C2778690821 @default.
• W2021436699 hasConcept C36823959 @default.
• W2021436699 hasConcept C54355233 @default.
• W2021436699 hasConcept C68324877 @default.
• W2021436699 hasConcept C86803240 @default.
• W2021436699 hasConcept C94671646 @default.
• W2021436699 hasConceptScore W2021436699C104317684 @default.
• W2021436699 hasConceptScore W2021436699C10858879 @default.
• W2021436699 hasConceptScore W2021436699C13373296 @default.
• W2021436699 hasConceptScore W2021436699C153911025 @default.
• W2021436699 hasConceptScore W2021436699C167625842 @default.
• W2021436699 hasConceptScore W2021436699C170493617 @default.
• W2021436699 hasConceptScore W2021436699C2778690821 @default.
• W2021436699 hasConceptScore W2021436699C36823959 @default.
• W2021436699 hasConceptScore W2021436699C54355233 @default.
• W2021436699 hasConceptScore W2021436699C68324877 @default.
• W2021436699 hasConceptScore W2021436699C86803240 @default.
• W2021436699 hasConceptScore W2021436699C94671646 @default.
• W2021436699 hasFunder F4320321001 @default.
• W2021436699 hasFunder F4320335777 @default.
• W2021436699 hasIssue "2" @default.

• next