Matches in SemOpenAlex for { <https://semopenalex.org/work/W2021443819> ?p ?o ?g. }
Showing items 1 to 94 of
94
with 100 items per page.
- W2021443819 endingPage "88" @default.
- W2021443819 startingPage "82" @default.
- W2021443819 abstract "This paper presents a novel Cadence™ single-pass tangential flow filtration (SPTFF) process for protein concentration, operating in a continuous mode. The main advantages of the SPTFF technology have been highlighted in a benchmark comparison test versus conventional TFF. SPTFF modules consist of internally staged T-series cassettes for creating longer flow paths that result in significantly higher conversion in one pass. This eliminates the need for the conventional TFF recirculation loop. SPTFF utilizes flow ratio control to achieve target concentration factors and final product concentrations instantaneously. Bovine IgG solutions in PBS (5–45 g/L) were processed to achieve a concentration factor range of 3–25×, which resulted in permeate fluxes in the range of 10–70 L/m2/h over a feed-side pressure drop range of 25–65 psid. Ten cycles of high concentration, product recovery and cleaning were successfully completed with the same SPTFF module to demonstrate experimental reproducibility and process stability. A ∼45 g/L IgG feed solution was concentrated to 190–225 g/L during all cycles resulting in high product recoveries in the range of 95.7–98.9%." @default.
- W2021443819 created "2016-06-24" @default.
- W2021443819 creator A5033016792 @default.
- W2021443819 creator A5036443456 @default.
- W2021443819 creator A5046789601 @default.
- W2021443819 creator A5077135976 @default.
- W2021443819 creator A5089657881 @default.
- W2021443819 date "2011-11-01" @default.
- W2021443819 modified "2023-10-09" @default.
- W2021443819 title "Protein concentration with single-pass tangential flow filtration (SPTFF)" @default.
- W2021443819 cites W1998550602 @default.
- W2021443819 cites W2002284346 @default.
- W2021443819 cites W2025851521 @default.
- W2021443819 cites W2031749836 @default.
- W2021443819 cites W2038052574 @default.
- W2021443819 cites W2050597308 @default.
- W2021443819 cites W2058052926 @default.
- W2021443819 cites W2058794164 @default.
- W2021443819 cites W2061382712 @default.
- W2021443819 cites W2074764245 @default.
- W2021443819 cites W2082568784 @default.
- W2021443819 cites W2110662148 @default.
- W2021443819 cites W2429586512 @default.
- W2021443819 cites W4246255427 @default.
- W2021443819 doi "https://doi.org/10.1016/j.memsci.2011.09.004" @default.
- W2021443819 hasPublicationYear "2011" @default.
- W2021443819 type Work @default.
- W2021443819 sameAs 2021443819 @default.
- W2021443819 citedByCount "70" @default.
- W2021443819 countsByYear W20214438192012 @default.
- W2021443819 countsByYear W20214438192013 @default.
- W2021443819 countsByYear W20214438192014 @default.
- W2021443819 countsByYear W20214438192015 @default.
- W2021443819 countsByYear W20214438192016 @default.
- W2021443819 countsByYear W20214438192017 @default.
- W2021443819 countsByYear W20214438192018 @default.
- W2021443819 countsByYear W20214438192019 @default.
- W2021443819 countsByYear W20214438192020 @default.
- W2021443819 countsByYear W20214438192021 @default.
- W2021443819 countsByYear W20214438192022 @default.
- W2021443819 countsByYear W20214438192023 @default.
- W2021443819 crossrefType "journal-article" @default.
- W2021443819 hasAuthorship W2021443819A5033016792 @default.
- W2021443819 hasAuthorship W2021443819A5036443456 @default.
- W2021443819 hasAuthorship W2021443819A5046789601 @default.
- W2021443819 hasAuthorship W2021443819A5077135976 @default.
- W2021443819 hasAuthorship W2021443819A5089657881 @default.
- W2021443819 hasConcept C105795698 @default.
- W2021443819 hasConcept C113196181 @default.
- W2021443819 hasConcept C114088122 @default.
- W2021443819 hasConcept C121332964 @default.
- W2021443819 hasConcept C128489963 @default.
- W2021443819 hasConcept C172120300 @default.
- W2021443819 hasConcept C185592680 @default.
- W2021443819 hasConcept C192562407 @default.
- W2021443819 hasConcept C33923547 @default.
- W2021443819 hasConcept C38349280 @default.
- W2021443819 hasConcept C43617362 @default.
- W2021443819 hasConcept C57879066 @default.
- W2021443819 hasConcept C9893847 @default.
- W2021443819 hasConceptScore W2021443819C105795698 @default.
- W2021443819 hasConceptScore W2021443819C113196181 @default.
- W2021443819 hasConceptScore W2021443819C114088122 @default.
- W2021443819 hasConceptScore W2021443819C121332964 @default.
- W2021443819 hasConceptScore W2021443819C128489963 @default.
- W2021443819 hasConceptScore W2021443819C172120300 @default.
- W2021443819 hasConceptScore W2021443819C185592680 @default.
- W2021443819 hasConceptScore W2021443819C192562407 @default.
- W2021443819 hasConceptScore W2021443819C33923547 @default.
- W2021443819 hasConceptScore W2021443819C38349280 @default.
- W2021443819 hasConceptScore W2021443819C43617362 @default.
- W2021443819 hasConceptScore W2021443819C57879066 @default.
- W2021443819 hasConceptScore W2021443819C9893847 @default.
- W2021443819 hasIssue "1-2" @default.
- W2021443819 hasLocation W20214438191 @default.
- W2021443819 hasOpenAccess W2021443819 @default.
- W2021443819 hasPrimaryLocation W20214438191 @default.
- W2021443819 hasRelatedWork W1480223519 @default.
- W2021443819 hasRelatedWork W150813677 @default.
- W2021443819 hasRelatedWork W1964674110 @default.
- W2021443819 hasRelatedWork W2000772114 @default.
- W2021443819 hasRelatedWork W2026756332 @default.
- W2021443819 hasRelatedWork W2385975420 @default.
- W2021443819 hasRelatedWork W2529017999 @default.
- W2021443819 hasRelatedWork W2605670789 @default.
- W2021443819 hasRelatedWork W2740818774 @default.
- W2021443819 hasRelatedWork W4206930520 @default.
- W2021443819 hasVolume "384" @default.
- W2021443819 isParatext "false" @default.
- W2021443819 isRetracted "false" @default.
- W2021443819 magId "2021443819" @default.
- W2021443819 workType "article" @default.