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• W2021445276 abstract "A series of phenylimidazole-pyrazolo[1,5-c]quinazolines 1a–q was designed, synthesized and characterised as a novel class of potent phophodiesterase 10A (PDE10A) inhibitors. In this series, 2,9-dimethyl-5-(2-(1-methyl-4-phenyl-1H-imidazol-2-yl)ethyl)pyrazolo[1,5-c]quinazoline (1q) showed the highest affinity for PDE10A enzyme (IC50 = 16 nM)." @default.
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• W2021445276 date "2011-01-01" @default.
• W2021445276 modified "2023-10-15" @default.
• W2021445276 title "Synthesis and SAR study of new phenylimidazole-pyrazolo[1,5-c]quinazolines as potent phosphodiesterase 10A inhibitors" @default.
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• W2021445276 doi "https://doi.org/10.1016/j.bmc.2010.10.038" @default.
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