FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2021502550> ?p ?o ?g. }

• W2021502550 endingPage "1909" @default.
• W2021502550 startingPage "1904" @default.
• W2021502550 abstract "New therapies are being developed that are antiatherosclerotic but that lack intermediate end points, such as changes in plasma lipids, which can be measured to test efficacy. To study such treatments, it will be necessary to directly measure changes in atherosclerosis. The study was designed to determine sample sizes needed to detect effects of treatment using 3D ultrasound (US) measurement of carotid plaque.In 38 patients with carotid stenosis >60%, age+/-SD 69.42+/-7.87 years, 15 female, randomly assigned in a double-blind fashion to 80 mg atorvastatin daily (n=17) versus placebo (n=21), we measured 3D plaque volume at baseline and after 3 months by disc segmentation of voxels representing carotid artery plaque, after 3D reconstruction of parallel transverse duplex US scans into volumetric 3D data sets.There were no significant differences in baseline risk factors. The rate of progression was 16.81+/-74.10 mm3 in patients taking placebo versus regression of -90.25+/-85.12 mm3 in patients taking atorvastatin (P<0.0001).3D plaque volume measurement can show large effects of therapy on atherosclerosis in 3 months in sample sizes of approximately 20 patients per group. Sample sizes of 22 per group would be sufficient to show an effect size of 25% that of atorvastatin in 6 months. This technology promises to be very useful in evaluation of new therapies." @default.
• W2021502550 created "2016-06-24" @default.
• W2021502550 creator A5002885761 @default.
• W2021502550 creator A5004966232 @default.
• W2021502550 creator A5014104597 @default.
• W2021502550 creator A5016780725 @default.
• W2021502550 creator A5028916111 @default.
• W2021502550 creator A5048325873 @default.
• W2021502550 date "2005-09-01" @default.
• W2021502550 modified "2023-10-10" @default.
• W2021502550 title "3D Ultrasound Measurement of Change in Carotid Plaque Volume" @default.
• W2021502550 cites W1930066242 @default.
• W2021502550 cites W1967744200 @default.
• W2021502550 cites W1968147458 @default.
• W2021502550 cites W1968510365 @default.
• W2021502550 cites W2005219553 @default.
• W2021502550 cites W2019789008 @default.
• W2021502550 cites W2033806728 @default.
• W2021502550 cites W2035142337 @default.
• W2021502550 cites W2070225917 @default.
• W2021502550 cites W2072230421 @default.
• W2021502550 cites W2080722797 @default.
• W2021502550 cites W2083914450 @default.
• W2021502550 cites W2091284732 @default.
• W2021502550 cites W2093617296 @default.
• W2021502550 cites W2095507444 @default.
• W2021502550 cites W2100563697 @default.
• W2021502550 cites W2125096763 @default.
• W2021502550 cites W2125801879 @default.
• W2021502550 cites W2144434947 @default.
• W2021502550 cites W2147891225 @default.
• W2021502550 cites W2152584226 @default.
• W2021502550 cites W2166910397 @default.
• W2021502550 cites W2316167515 @default.
• W2021502550 cites W2332155718 @default.
• W2021502550 cites W2397128705 @default.
• W2021502550 cites W71984142 @default.
• W2021502550 doi "https://doi.org/10.1161/01.str.0000178543.19433.20" @default.
• W2021502550 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16081857" @default.
• W2021502550 hasPublicationYear "2005" @default.
• W2021502550 type Work @default.
• W2021502550 sameAs 2021502550 @default.
• W2021502550 citedByCount "234" @default.
• W2021502550 countsByYear W20215025502012 @default.
• W2021502550 countsByYear W20215025502013 @default.
• W2021502550 countsByYear W20215025502014 @default.
• W2021502550 countsByYear W20215025502015 @default.
• W2021502550 countsByYear W20215025502016 @default.
• W2021502550 countsByYear W20215025502017 @default.
• W2021502550 countsByYear W20215025502018 @default.
• W2021502550 countsByYear W20215025502019 @default.
• W2021502550 countsByYear W20215025502020 @default.
• W2021502550 countsByYear W20215025502021 @default.
• W2021502550 countsByYear W20215025502022 @default.
• W2021502550 countsByYear W20215025502023 @default.
• W2021502550 crossrefType "journal-article" @default.
• W2021502550 hasAuthorship W2021502550A5002885761 @default.
• W2021502550 hasAuthorship W2021502550A5004966232 @default.
• W2021502550 hasAuthorship W2021502550A5014104597 @default.
• W2021502550 hasAuthorship W2021502550A5016780725 @default.
• W2021502550 hasAuthorship W2021502550A5028916111 @default.
• W2021502550 hasAuthorship W2021502550A5048325873 @default.
• W2021502550 hasBestOaLocation W20215025501 @default.
• W2021502550 hasConcept C105795698 @default.
• W2021502550 hasConcept C126322002 @default.
• W2021502550 hasConcept C126838900 @default.
• W2021502550 hasConcept C126894567 @default.
• W2021502550 hasConcept C129848803 @default.
• W2021502550 hasConcept C142724271 @default.
• W2021502550 hasConcept C143753070 @default.
• W2021502550 hasConcept C164705383 @default.
• W2021502550 hasConcept C204787440 @default.
• W2021502550 hasConcept C27081682 @default.
• W2021502550 hasConcept C2777482532 @default.
• W2021502550 hasConcept C2780170424 @default.
• W2021502550 hasConcept C2781064879 @default.
• W2021502550 hasConcept C2987047532 @default.
• W2021502550 hasConcept C2989005 @default.
• W2021502550 hasConcept C33923547 @default.
• W2021502550 hasConcept C54170458 @default.
• W2021502550 hasConcept C71924100 @default.
• W2021502550 hasConceptScore W2021502550C105795698 @default.
• W2021502550 hasConceptScore W2021502550C126322002 @default.
• W2021502550 hasConceptScore W2021502550C126838900 @default.
• W2021502550 hasConceptScore W2021502550C126894567 @default.
• W2021502550 hasConceptScore W2021502550C129848803 @default.
• W2021502550 hasConceptScore W2021502550C142724271 @default.
• W2021502550 hasConceptScore W2021502550C143753070 @default.
• W2021502550 hasConceptScore W2021502550C164705383 @default.
• W2021502550 hasConceptScore W2021502550C204787440 @default.
• W2021502550 hasConceptScore W2021502550C27081682 @default.
• W2021502550 hasConceptScore W2021502550C2777482532 @default.
• W2021502550 hasConceptScore W2021502550C2780170424 @default.
• W2021502550 hasConceptScore W2021502550C2781064879 @default.
• W2021502550 hasConceptScore W2021502550C2987047532 @default.
• W2021502550 hasConceptScore W2021502550C2989005 @default.
• W2021502550 hasConceptScore W2021502550C33923547 @default.
• W2021502550 hasConceptScore W2021502550C54170458 @default.

• next