FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2021504367> ?p ?o ?g. }

• W2021504367 abstract "A sensitive and analytically specific nucleic acid amplification test (NAAT) is valuable in confirming the diagnosis of early Lyme disease at the stage of spirochetemia.Venous blood drawn from patients with clinical presentations of Lyme disease was tested for the standard 2-tier screen and Western Blot serology assay for Lyme disease, and also by a nested polymerase chain reaction (PCR) for B. burgdorferi sensu lato 16S ribosomal DNA. The PCR amplicon was sequenced for B. burgdorferi genomic DNA validation. A total of 130 patients visiting emergency room (ER) or Walk-in clinic (WALKIN), and 333 patients referred through the private physicians' offices were studied. While 5.4% of the ER/WALKIN patients showed DNA evidence of spirochetemia, none (0%) of the patients referred from private physicians' offices were DNA-positive. In contrast, while 8.4% of the patients referred from private physicians' offices were positive for the 2-tier Lyme serology assay, only 1.5% of the ER/WALKIN patients were positive for this antibody test. The 2-tier serology assay missed 85.7% of the cases of early Lyme disease with spirochetemia. The latter diagnosis was confirmed by DNA sequencing.Nested PCR followed by automated DNA sequencing is a valuable supplement to the standard 2-tier antibody assay in the diagnosis of early Lyme disease with spirochetemia. The best time to test for Lyme spirochetemia is when the patients living in the Lyme disease endemic areas develop unexplained symptoms or clinical manifestations that are consistent with Lyme disease early in the course of their illness." @default.
• W2021504367 created "2016-06-24" @default.
• W2021504367 creator A5012967092 @default.
• W2021504367 creator A5033122119 @default.
• W2021504367 creator A5038109879 @default.
• W2021504367 creator A5046414792 @default.
• W2021504367 creator A5076389805 @default.
• W2021504367 creator A5085902322 @default.
• W2021504367 date "2010-11-01" @default.
• W2021504367 modified "2023-10-10" @default.
• W2021504367 title "Early Lyme disease with spirochetemia - diagnosed by DNA sequencing" @default.
• W2021504367 cites W1976117629 @default.
• W2021504367 cites W1991356715 @default.
• W2021504367 cites W2014799977 @default.
• W2021504367 cites W2025416912 @default.
• W2021504367 cites W2028983624 @default.
• W2021504367 cites W2047344093 @default.
• W2021504367 cites W2051609607 @default.
• W2021504367 cites W2081728261 @default.
• W2021504367 cites W2085062917 @default.
• W2021504367 cites W2097770204 @default.
• W2021504367 cites W2118743404 @default.
• W2021504367 cites W2125641599 @default.
• W2021504367 cites W2132546705 @default.
• W2021504367 cites W2139104181 @default.
• W2021504367 cites W2141152593 @default.
• W2021504367 cites W2147955113 @default.
• W2021504367 cites W2153086895 @default.
• W2021504367 cites W2163586341 @default.
• W2021504367 doi "https://doi.org/10.1186/1756-0500-3-273" @default.
• W2021504367 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2984391" @default.
• W2021504367 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/21040573" @default.
• W2021504367 hasPublicationYear "2010" @default.
• W2021504367 type Work @default.
• W2021504367 sameAs 2021504367 @default.
• W2021504367 citedByCount "8" @default.
• W2021504367 countsByYear W20215043672013 @default.
• W2021504367 countsByYear W20215043672014 @default.
• W2021504367 countsByYear W20215043672016 @default.
• W2021504367 countsByYear W20215043672018 @default.
• W2021504367 countsByYear W20215043672019 @default.
• W2021504367 countsByYear W20215043672021 @default.
• W2021504367 crossrefType "journal-article" @default.
• W2021504367 hasAuthorship W2021504367A5012967092 @default.
• W2021504367 hasAuthorship W2021504367A5033122119 @default.
• W2021504367 hasAuthorship W2021504367A5038109879 @default.
• W2021504367 hasAuthorship W2021504367A5046414792 @default.
• W2021504367 hasAuthorship W2021504367A5076389805 @default.
• W2021504367 hasAuthorship W2021504367A5085902322 @default.
• W2021504367 hasBestOaLocation W20215043671 @default.
• W2021504367 hasConcept C104317684 @default.
• W2021504367 hasConcept C126322002 @default.
• W2021504367 hasConcept C157431215 @default.
• W2021504367 hasConcept C159047783 @default.
• W2021504367 hasConcept C159654299 @default.
• W2021504367 hasConcept C203014093 @default.
• W2021504367 hasConcept C2776307562 @default.
• W2021504367 hasConcept C2777553296 @default.
• W2021504367 hasConcept C2779159148 @default.
• W2021504367 hasConcept C40993552 @default.
• W2021504367 hasConcept C45189115 @default.
• W2021504367 hasConcept C49105822 @default.
• W2021504367 hasConcept C54355233 @default.
• W2021504367 hasConcept C71924100 @default.
• W2021504367 hasConcept C86803240 @default.
• W2021504367 hasConceptScore W2021504367C104317684 @default.
• W2021504367 hasConceptScore W2021504367C126322002 @default.
• W2021504367 hasConceptScore W2021504367C157431215 @default.
• W2021504367 hasConceptScore W2021504367C159047783 @default.
• W2021504367 hasConceptScore W2021504367C159654299 @default.
• W2021504367 hasConceptScore W2021504367C203014093 @default.
• W2021504367 hasConceptScore W2021504367C2776307562 @default.
• W2021504367 hasConceptScore W2021504367C2777553296 @default.
• W2021504367 hasConceptScore W2021504367C2779159148 @default.
• W2021504367 hasConceptScore W2021504367C40993552 @default.
• W2021504367 hasConceptScore W2021504367C45189115 @default.
• W2021504367 hasConceptScore W2021504367C49105822 @default.
• W2021504367 hasConceptScore W2021504367C54355233 @default.
• W2021504367 hasConceptScore W2021504367C71924100 @default.
• W2021504367 hasConceptScore W2021504367C86803240 @default.
• W2021504367 hasIssue "1" @default.
• W2021504367 hasLocation W20215043671 @default.
• W2021504367 hasLocation W20215043672 @default.
• W2021504367 hasLocation W20215043673 @default.
• W2021504367 hasLocation W20215043674 @default.
• W2021504367 hasOpenAccess W2021504367 @default.
• W2021504367 hasPrimaryLocation W20215043671 @default.
• W2021504367 hasRelatedWork W166370195 @default.
• W2021504367 hasRelatedWork W2020013239 @default.
• W2021504367 hasRelatedWork W2056982387 @default.
• W2021504367 hasRelatedWork W2126204237 @default.
• W2021504367 hasRelatedWork W2165151366 @default.
• W2021504367 hasRelatedWork W2467650560 @default.
• W2021504367 hasRelatedWork W2530117033 @default.
• W2021504367 hasRelatedWork W3190603120 @default.
• W2021504367 hasRelatedWork W39666760 @default.
• W2021504367 hasRelatedWork W4230438789 @default.
• W2021504367 hasVolume "3" @default.
• W2021504367 isParatext "false" @default.
• W2021504367 isRetracted "false" @default.

• next