FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2021505510> ?p ?o ?g. }

• W2021505510 endingPage "517" @default.
• W2021505510 startingPage "497" @default.
• W2021505510 abstract "Recent improvements in the results of orthotopic liver transplantation (OLT) have made this a well-accepted treatment for patients with severe hepatic failure. Current problems encountered following OLT are discussed. Immediate complications comprise surgical bleeding, primary graft non-function, and graft failure due to hepatic artery occlusion. Secondary complications are frequent. Surgical ones include biliary and vascular (hepatic artery thrombosis most often) problems, as well as intra-abdominal abscesses associated with gastrointestinal perforation, biliary leak, graft ischaemia or an infected haematoma. 40% of patients having undergone OLT will be reoperated on, 2/3 of them within 3 months. Non-surgical complications are mostly pulmonary. The risk of pneumonitis is increased by prolonged mechanical ventilation; it is always potentially disastrous in the immunosuppressed, transplanted patient. Hypertension is also often seen in the early postoperative period; it requires prompt treatment. Early renal impairment after OLT is common, and of better prognosis than late onset renal failure, which is generally associated with shock, graft failure, sepsis or use of nephrotoxic agents. Seizures, usually only one, occur in about 10% of patients; recovery is complete. Encephalopathy with intracranial oedema related to fulminant hepatitis has a worse prognosis, but survival figures are quite encouraging. Three type of rejection are described after OLT: 1) severe accelerated rejection (very rare), 2) acute rejection encountered in about 70% of patients over the first 3 months, and 3) late rejection, which can lead to the vanishing bile duct syndrome (VBDS). Diagnosis of rejection is made by liver biopsy. Prophylactic immunosuppression includes cyclosporin, methylprednisolone and azathioprine. Cyclosporin toxicity and drug interactions are reviewed. Treatment of acute rejection episodes comprises an initial bolus of high doses of corticoid drugs; if there is no response, antilymphocyte globulin or monoclonal antibodies may have to be used. Infection is the main cause of death following OLT. Early infections, mostly intra-abdominal and pulmonary, are bacterial or fungal. Vital (especially CMV) and other opportunistic infections occur generally after the second week. Retransplantation, carried out in 10 to 25% of patients, may be urgent in case of primary graft failure, or hepatic artery thrombosis associated with graft failure, or hepatic artery thrombosis associated with graft failure. Other indications are early graft rejection with severe hepatic dysfunction, chronic rejection with severe VBDS, and recurrence of the initial disease." @default.
• W2021505510 created "2016-06-24" @default.
• W2021505510 creator A5015567386 @default.
• W2021505510 creator A5026625566 @default.
• W2021505510 creator A5029474235 @default.
• W2021505510 creator A5040018177 @default.
• W2021505510 creator A5057798513 @default.
• W2021505510 creator A5058081105 @default.
• W2021505510 creator A5074899911 @default.
• W2021505510 creator A5081044413 @default.
• W2021505510 creator A5083846645 @default.
• W2021505510 creator A5088371468 @default.
• W2021505510 date "1989-01-01" @default.
• W2021505510 modified "2023-09-27" @default.
• W2021505510 title "Transplantation hépatique chez l'adulte : prise en charge postopératoire et évolution au cours des premiers mois" @default.
• W2021505510 cites W147473274 @default.
• W2021505510 cites W1523616557 @default.
• W2021505510 cites W1570138415 @default.
• W2021505510 cites W1603638978 @default.
• W2021505510 cites W1963969155 @default.
• W2021505510 cites W1964718311 @default.
• W2021505510 cites W1965009448 @default.
• W2021505510 cites W1966198810 @default.
• W2021505510 cites W1967271305 @default.
• W2021505510 cites W1968431172 @default.
• W2021505510 cites W1968554411 @default.
• W2021505510 cites W1969055818 @default.
• W2021505510 cites W1970924209 @default.
• W2021505510 cites W1971441603 @default.
• W2021505510 cites W1971734830 @default.
• W2021505510 cites W1975759226 @default.
• W2021505510 cites W1975793142 @default.
• W2021505510 cites W1977260184 @default.
• W2021505510 cites W1977824869 @default.
• W2021505510 cites W1978259555 @default.
• W2021505510 cites W1981340033 @default.
• W2021505510 cites W1983375674 @default.
• W2021505510 cites W1984731911 @default.
• W2021505510 cites W1986105149 @default.
• W2021505510 cites W1986246266 @default.
• W2021505510 cites W1987013299 @default.
• W2021505510 cites W1987985804 @default.
• W2021505510 cites W1988691018 @default.
• W2021505510 cites W1990016536 @default.
• W2021505510 cites W1991700718 @default.
• W2021505510 cites W1991942320 @default.
• W2021505510 cites W1993874069 @default.
• W2021505510 cites W1995884105 @default.
• W2021505510 cites W1996694750 @default.
• W2021505510 cites W1998598764 @default.
• W2021505510 cites W2000460086 @default.
• W2021505510 cites W2000547547 @default.
• W2021505510 cites W2004229504 @default.
• W2021505510 cites W2004660649 @default.
• W2021505510 cites W2005510611 @default.
• W2021505510 cites W2005548491 @default.
• W2021505510 cites W2006249612 @default.
• W2021505510 cites W2007472171 @default.
• W2021505510 cites W2009619412 @default.
• W2021505510 cites W2010774403 @default.
• W2021505510 cites W2011293155 @default.
• W2021505510 cites W2011912116 @default.
• W2021505510 cites W2012837452 @default.
• W2021505510 cites W2014470485 @default.
• W2021505510 cites W2014529081 @default.
• W2021505510 cites W2014806496 @default.
• W2021505510 cites W2015117382 @default.
• W2021505510 cites W2018051522 @default.
• W2021505510 cites W2018182134 @default.
• W2021505510 cites W2018911073 @default.
• W2021505510 cites W2021429181 @default.
• W2021505510 cites W2021915744 @default.
• W2021505510 cites W2024428413 @default.
• W2021505510 cites W2025492739 @default.
• W2021505510 cites W2025861264 @default.
• W2021505510 cites W2026342716 @default.
• W2021505510 cites W2026823408 @default.
• W2021505510 cites W2027513535 @default.
• W2021505510 cites W2027588478 @default.
• W2021505510 cites W2027922729 @default.
• W2021505510 cites W2029662924 @default.
• W2021505510 cites W2030662803 @default.
• W2021505510 cites W2030692307 @default.
• W2021505510 cites W2031714088 @default.
• W2021505510 cites W2031841518 @default.
• W2021505510 cites W2033453933 @default.
• W2021505510 cites W2034822577 @default.
• W2021505510 cites W2036218762 @default.
• W2021505510 cites W2039735164 @default.
• W2021505510 cites W2041535522 @default.
• W2021505510 cites W2042856864 @default.
• W2021505510 cites W2042868727 @default.
• W2021505510 cites W2044738352 @default.
• W2021505510 cites W2046466271 @default.
• W2021505510 cites W2047711152 @default.
• W2021505510 cites W2047928642 @default.
• W2021505510 cites W2049680953 @default.
• W2021505510 cites W2051770321 @default.

• next