FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2021506525> ?p ?o ?g. }

• W2021506525 endingPage "1272" @default.
• W2021506525 startingPage "1268" @default.
• W2021506525 abstract "Pure porcine cholecystokinin-33 [the triacontatriapeptide form of cholecystokinin (CCK-33)], gastric inhibitory polypeptide (GIP), and secretin were infused in rats in doses of 1, 10, and 100 pmol/kg·min. The pep tides were administered alone or in combination with glucose (40 mg/kg·min) or arginine (50 mg/kg·min). In the basal state, CCK-33 and GIP produced significant hypoglycemia at all concentrations used, although they elevated insulin levels only at the highest dose. Secretin had no effect. CCK-33 at a dose of 1 pmol/kg·min enhanced the secretion of insulin induced by glucose or arginine. These effects were more pronounced when higher doses of CCK-33 were administered. GIP at a dose of 1 pmol/kg·min had no effect on insulin release. Higher doses of GIP significantly potentiated insulin release stimulated by glucose or arginine. Secretin (100 pmol/kg·min) had no clear-cut effect on glucose-induced insulin secretion, but it slightly enhanced arginine-induced secretion. All hormones investigated, at all doses used, significantly stimulated the arginine-induced secretion of glucagon. We conclude that CCK-33 is a potent stimulatory factor of glucose-and arginine-induced insulin secretion and should therefore be taken into consideration as an incretin candidate. In addition, CCK-33 and GIP modulate glucose homeostasis by affecting glucagon release." @default.
• W2021506525 created "2016-06-24" @default.
• W2021506525 creator A5007308043 @default.
• W2021506525 creator A5013305995 @default.
• W2021506525 creator A5042723115 @default.
• W2021506525 date "1982-04-01" @default.
• W2021506525 modified "2023-10-15" @default.
• W2021506525 title "Effects of Cholecystokinin, Gastric Inhibitory Polypeptide, and Secretin on Insulin and Glucagon Secretion in Rats*" @default.
• W2021506525 cites W1033637655 @default.
• W2021506525 cites W1965864594 @default.
• W2021506525 cites W1975624480 @default.
• W2021506525 cites W1982094574 @default.
• W2021506525 cites W1994989824 @default.
• W2021506525 cites W1996519966 @default.
• W2021506525 cites W2019953645 @default.
• W2021506525 cites W2036106263 @default.
• W2021506525 cites W2042570720 @default.
• W2021506525 cites W2044170077 @default.
• W2021506525 cites W2047662831 @default.
• W2021506525 cites W2049120916 @default.
• W2021506525 cites W2051743127 @default.
• W2021506525 cites W2055894260 @default.
• W2021506525 cites W2075404533 @default.
• W2021506525 cites W2078073869 @default.
• W2021506525 cites W2081004928 @default.
• W2021506525 cites W2095675059 @default.
• W2021506525 cites W2104100980 @default.
• W2021506525 cites W2111241270 @default.
• W2021506525 cites W2169558934 @default.
• W2021506525 doi "https://doi.org/10.1210/endo-110-4-1268" @default.
• W2021506525 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/7037370" @default.
• W2021506525 hasPublicationYear "1982" @default.
• W2021506525 type Work @default.
• W2021506525 sameAs 2021506525 @default.
• W2021506525 citedByCount "77" @default.
• W2021506525 countsByYear W20215065252013 @default.
• W2021506525 countsByYear W20215065252015 @default.
• W2021506525 countsByYear W20215065252021 @default.
• W2021506525 countsByYear W20215065252022 @default.
• W2021506525 crossrefType "journal-article" @default.
• W2021506525 hasAuthorship W2021506525A5007308043 @default.
• W2021506525 hasAuthorship W2021506525A5013305995 @default.
• W2021506525 hasAuthorship W2021506525A5042723115 @default.
• W2021506525 hasConcept C126322002 @default.
• W2021506525 hasConcept C134018914 @default.
• W2021506525 hasConcept C170493617 @default.
• W2021506525 hasConcept C185592680 @default.
• W2021506525 hasConcept C2776129832 @default.
• W2021506525 hasConcept C2777180221 @default.
• W2021506525 hasConcept C2777391703 @default.
• W2021506525 hasConcept C2777468819 @default.
• W2021506525 hasConcept C2777593968 @default.
• W2021506525 hasConcept C2777951760 @default.
• W2021506525 hasConcept C2778563252 @default.
• W2021506525 hasConcept C2778677841 @default.
• W2021506525 hasConcept C2778881409 @default.
• W2021506525 hasConcept C2779306644 @default.
• W2021506525 hasConcept C3018667095 @default.
• W2021506525 hasConcept C49039625 @default.
• W2021506525 hasConcept C515207424 @default.
• W2021506525 hasConcept C55493867 @default.
• W2021506525 hasConcept C555293320 @default.
• W2021506525 hasConcept C56191518 @default.
• W2021506525 hasConcept C71315377 @default.
• W2021506525 hasConcept C71924100 @default.
• W2021506525 hasConcept C86803240 @default.
• W2021506525 hasConceptScore W2021506525C126322002 @default.
• W2021506525 hasConceptScore W2021506525C134018914 @default.
• W2021506525 hasConceptScore W2021506525C170493617 @default.
• W2021506525 hasConceptScore W2021506525C185592680 @default.
• W2021506525 hasConceptScore W2021506525C2776129832 @default.
• W2021506525 hasConceptScore W2021506525C2777180221 @default.
• W2021506525 hasConceptScore W2021506525C2777391703 @default.
• W2021506525 hasConceptScore W2021506525C2777468819 @default.
• W2021506525 hasConceptScore W2021506525C2777593968 @default.
• W2021506525 hasConceptScore W2021506525C2777951760 @default.
• W2021506525 hasConceptScore W2021506525C2778563252 @default.
• W2021506525 hasConceptScore W2021506525C2778677841 @default.
• W2021506525 hasConceptScore W2021506525C2778881409 @default.
• W2021506525 hasConceptScore W2021506525C2779306644 @default.
• W2021506525 hasConceptScore W2021506525C3018667095 @default.
• W2021506525 hasConceptScore W2021506525C49039625 @default.
• W2021506525 hasConceptScore W2021506525C515207424 @default.
• W2021506525 hasConceptScore W2021506525C55493867 @default.
• W2021506525 hasConceptScore W2021506525C555293320 @default.
• W2021506525 hasConceptScore W2021506525C56191518 @default.
• W2021506525 hasConceptScore W2021506525C71315377 @default.
• W2021506525 hasConceptScore W2021506525C71924100 @default.
• W2021506525 hasConceptScore W2021506525C86803240 @default.
• W2021506525 hasIssue "4" @default.
• W2021506525 hasLocation W20215065251 @default.
• W2021506525 hasLocation W20215065252 @default.
• W2021506525 hasOpenAccess W2021506525 @default.
• W2021506525 hasPrimaryLocation W20215065251 @default.
• W2021506525 hasRelatedWork W1998612309 @default.
• W2021506525 hasRelatedWork W199940865 @default.
• W2021506525 hasRelatedWork W2019953645 @default.
• W2021506525 hasRelatedWork W2021506525 @default.

• next