Matches in SemOpenAlex for { <https://semopenalex.org/work/W2021506847> ?p ?o ?g. }
Showing items 1 to 90 of
90
with 100 items per page.
- W2021506847 endingPage "289" @default.
- W2021506847 startingPage "285" @default.
- W2021506847 abstract "Because benign prostatic hyperplasia (BPH) may be influenced by plasma steroid hormones, we examined their relation in the Health Professionals Follow-up Study. In 1993–1995, 18,000 cohort members provided blood. We selected as cases men who had had surgery for BPH (n=174) or who scored 20–35 points (n=126) on the American Urological Association index of severity of lower urinary tract symptoms. Cases were matched by age to men who scored≤3 points and without an enlarged prostate or elevated prostate-specific antigen. We estimated the odds ratio (OR) of BPH surgery and severe lower urinary tract symptoms for plasma testosterone (T), dihydrotestosterone (DHT), androstanediol glucuronide (AAG), estradiol (E2), and sex hormone binding globulin (SHBG) in multivariable conditional logistic regression models. Compared to the lowest tertiles, men in the middle (OR=1.42) and top (OR=1.78) tertiles of AAG were at increased risk for having either BPH surgery or severe lower urinary tract symptoms (P-trend=0.02). Men in the middle (OR=0.58) and top (OR=0.60) tertiles of E2 were at lower risk. T level was unrelated to surgery and symptoms. Our findings support opposing roles for DHT, reflected by its metabolite AAG, and E2 in the etiology of BPH." @default.
- W2021506847 created "2016-06-24" @default.
- W2021506847 creator A5009711086 @default.
- W2021506847 creator A5023980841 @default.
- W2021506847 creator A5038373228 @default.
- W2021506847 creator A5056849976 @default.
- W2021506847 creator A5069446446 @default.
- W2021506847 creator A5077114833 @default.
- W2021506847 creator A5083421561 @default.
- W2021506847 date "1999-12-01" @default.
- W2021506847 modified "2023-10-17" @default.
- W2021506847 title "Plasma steroid hormones, surgery for benign prostatic hyperplasia, and severe lower urinary tract symptoms" @default.
- W2021506847 doi "https://doi.org/10.1038/sj.pcan.4500380" @default.
- W2021506847 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/12497176" @default.
- W2021506847 hasPublicationYear "1999" @default.
- W2021506847 type Work @default.
- W2021506847 sameAs 2021506847 @default.
- W2021506847 citedByCount "23" @default.
- W2021506847 countsByYear W20215068472012 @default.
- W2021506847 countsByYear W20215068472014 @default.
- W2021506847 countsByYear W20215068472017 @default.
- W2021506847 crossrefType "journal-article" @default.
- W2021506847 hasAuthorship W2021506847A5009711086 @default.
- W2021506847 hasAuthorship W2021506847A5023980841 @default.
- W2021506847 hasAuthorship W2021506847A5038373228 @default.
- W2021506847 hasAuthorship W2021506847A5056849976 @default.
- W2021506847 hasAuthorship W2021506847A5069446446 @default.
- W2021506847 hasAuthorship W2021506847A5077114833 @default.
- W2021506847 hasAuthorship W2021506847A5083421561 @default.
- W2021506847 hasBestOaLocation W20215068471 @default.
- W2021506847 hasConcept C121608353 @default.
- W2021506847 hasConcept C126322002 @default.
- W2021506847 hasConcept C126894567 @default.
- W2021506847 hasConcept C134018914 @default.
- W2021506847 hasConcept C137627325 @default.
- W2021506847 hasConcept C156957248 @default.
- W2021506847 hasConcept C2775874879 @default.
- W2021506847 hasConcept C2776235491 @default.
- W2021506847 hasConcept C2777562237 @default.
- W2021506847 hasConcept C2777911890 @default.
- W2021506847 hasConcept C2779279991 @default.
- W2021506847 hasConcept C2779478474 @default.
- W2021506847 hasConcept C2779881493 @default.
- W2021506847 hasConcept C2910675164 @default.
- W2021506847 hasConcept C2994223898 @default.
- W2021506847 hasConcept C30092816 @default.
- W2021506847 hasConcept C71315377 @default.
- W2021506847 hasConcept C71924100 @default.
- W2021506847 hasConcept C77411442 @default.
- W2021506847 hasConceptScore W2021506847C121608353 @default.
- W2021506847 hasConceptScore W2021506847C126322002 @default.
- W2021506847 hasConceptScore W2021506847C126894567 @default.
- W2021506847 hasConceptScore W2021506847C134018914 @default.
- W2021506847 hasConceptScore W2021506847C137627325 @default.
- W2021506847 hasConceptScore W2021506847C156957248 @default.
- W2021506847 hasConceptScore W2021506847C2775874879 @default.
- W2021506847 hasConceptScore W2021506847C2776235491 @default.
- W2021506847 hasConceptScore W2021506847C2777562237 @default.
- W2021506847 hasConceptScore W2021506847C2777911890 @default.
- W2021506847 hasConceptScore W2021506847C2779279991 @default.
- W2021506847 hasConceptScore W2021506847C2779478474 @default.
- W2021506847 hasConceptScore W2021506847C2779881493 @default.
- W2021506847 hasConceptScore W2021506847C2910675164 @default.
- W2021506847 hasConceptScore W2021506847C2994223898 @default.
- W2021506847 hasConceptScore W2021506847C30092816 @default.
- W2021506847 hasConceptScore W2021506847C71315377 @default.
- W2021506847 hasConceptScore W2021506847C71924100 @default.
- W2021506847 hasConceptScore W2021506847C77411442 @default.
- W2021506847 hasIssue "5-6" @default.
- W2021506847 hasLocation W20215068471 @default.
- W2021506847 hasLocation W20215068472 @default.
- W2021506847 hasOpenAccess W2021506847 @default.
- W2021506847 hasPrimaryLocation W20215068471 @default.
- W2021506847 hasRelatedWork W2007166173 @default.
- W2021506847 hasRelatedWork W2021424019 @default.
- W2021506847 hasRelatedWork W2023481449 @default.
- W2021506847 hasRelatedWork W2044933954 @default.
- W2021506847 hasRelatedWork W2068637115 @default.
- W2021506847 hasRelatedWork W2069083739 @default.
- W2021506847 hasRelatedWork W2079213361 @default.
- W2021506847 hasRelatedWork W2149470433 @default.
- W2021506847 hasRelatedWork W2321629993 @default.
- W2021506847 hasRelatedWork W4382404610 @default.
- W2021506847 hasVolume "2" @default.
- W2021506847 isParatext "false" @default.
- W2021506847 isRetracted "false" @default.
- W2021506847 magId "2021506847" @default.
- W2021506847 workType "article" @default.