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• W2021511207 abstract "RationaleMost egg allergic children (EAC) are denied the influenza vaccine because of fear of allergic reaction despite no recent studies reporting serious allergic reaction. We wanted to report our experience with influenza vaccination in EAC.MethodsRetrospective chart review of EAC who received influenza vaccine at the Montreal Children Hospital between 2000 and 2006.ResultsOne hundred fifteen EAC received 173 doses (not including booster doses) of influenza vaccine either Fluviral® or Vaxigrip®. Reason for vaccination was asthma in 64%. Twelve percent of doses were preceded by intradermal skin test (dilution 1:10 or 1:100) of which 29% were positive. Fifty percent of doses were given as a single dose of which 69% were given to patients that had tolerated the vaccine before. Forty-five percent of doses were given in 2 steps (10% and 90% of the dose given 30 minutes apart) and 5% in 3 or more steps. Ninety-three percent of vaccination caused no reaction including all doses that were preceded by positive intradermal skin test. Six doses caused minor immediate local reactions. Three doses caused one facial urticarial plaque shortly after vaccination that resolved quickly. Three doses caused symptoms likely related to the act of vaccination (anxiety/vasovagal reactions). An additionnal 67 booster doses were given and none led to reaction.ConclusionsNone of EAC who received the influenza vaccine developed serious allergic reaction with nearly half receiving it as a single dose. Prospective studies are needed to assess safety of administering a single dose of this vaccine in that population. RationaleMost egg allergic children (EAC) are denied the influenza vaccine because of fear of allergic reaction despite no recent studies reporting serious allergic reaction. We wanted to report our experience with influenza vaccination in EAC. Most egg allergic children (EAC) are denied the influenza vaccine because of fear of allergic reaction despite no recent studies reporting serious allergic reaction. We wanted to report our experience with influenza vaccination in EAC. MethodsRetrospective chart review of EAC who received influenza vaccine at the Montreal Children Hospital between 2000 and 2006. Retrospective chart review of EAC who received influenza vaccine at the Montreal Children Hospital between 2000 and 2006. ResultsOne hundred fifteen EAC received 173 doses (not including booster doses) of influenza vaccine either Fluviral® or Vaxigrip®. Reason for vaccination was asthma in 64%. Twelve percent of doses were preceded by intradermal skin test (dilution 1:10 or 1:100) of which 29% were positive. Fifty percent of doses were given as a single dose of which 69% were given to patients that had tolerated the vaccine before. Forty-five percent of doses were given in 2 steps (10% and 90% of the dose given 30 minutes apart) and 5% in 3 or more steps. Ninety-three percent of vaccination caused no reaction including all doses that were preceded by positive intradermal skin test. Six doses caused minor immediate local reactions. Three doses caused one facial urticarial plaque shortly after vaccination that resolved quickly. Three doses caused symptoms likely related to the act of vaccination (anxiety/vasovagal reactions). An additionnal 67 booster doses were given and none led to reaction. One hundred fifteen EAC received 173 doses (not including booster doses) of influenza vaccine either Fluviral® or Vaxigrip®. Reason for vaccination was asthma in 64%. Twelve percent of doses were preceded by intradermal skin test (dilution 1:10 or 1:100) of which 29% were positive. Fifty percent of doses were given as a single dose of which 69% were given to patients that had tolerated the vaccine before. Forty-five percent of doses were given in 2 steps (10% and 90% of the dose given 30 minutes apart) and 5% in 3 or more steps. Ninety-three percent of vaccination caused no reaction including all doses that were preceded by positive intradermal skin test. Six doses caused minor immediate local reactions. Three doses caused one facial urticarial plaque shortly after vaccination that resolved quickly. Three doses caused symptoms likely related to the act of vaccination (anxiety/vasovagal reactions). An additionnal 67 booster doses were given and none led to reaction. ConclusionsNone of EAC who received the influenza vaccine developed serious allergic reaction with nearly half receiving it as a single dose. Prospective studies are needed to assess safety of administering a single dose of this vaccine in that population. None of EAC who received the influenza vaccine developed serious allergic reaction with nearly half receiving it as a single dose. Prospective studies are needed to assess safety of administering a single dose of this vaccine in that population." @default.
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• W2021511207 date "2008-02-01" @default.
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• W2021511207 title "A 6-year Experience with Influenza Vaccination in Egg Allergic Patients" @default.
• W2021511207 doi "https://doi.org/10.1016/j.jaci.2007.12.947" @default.
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