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- W2021522014 abstract "Abstract Hepatocytes isolated from rat fetuses have been shown to contain Systems A, ASC, and N for the Na+-dependent transport of neutral amino acids and the activity of each of these systems is significantly higher in the fetal cells than those of an adult (J. Vadgama and H.N. Christensen, personal communication). In contrast to the hepatocytes isolated from adult or newborn animals, the fetal cells do not respond to insulin, glucagon, or dexamethasone with an increase in System A-mediated transport. The System A activity present in the fetal hepatocytes does undergo adaptive regulation in a manner similar to that seen for adult cells, however, the same is not true for System N. Like the cells isolated from the adult rats, the hepatocytes isolated from fetal liver tissue exhibit an increase in Na+-independent transport with time in culture." @default.
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- W2021522014 date "1982-10-01" @default.
- W2021522014 modified "2023-09-27" @default.
- W2021522014 title "Transport System A is not responsive to hormonal stimulation in primary cultures of fetal rat hepatocytes" @default.
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- W2021522014 doi "https://doi.org/10.1016/0006-291x(82)92115-5" @default.
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