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- W2021551854 abstract "Using phase-separated droplet interface bilayers, we observe membrane binding and pore formation of a eukaryotic cytolysin, Equinatoxin II (EqtII). EqtII activity is known to depend on the presence of sphingomyelin in the target membrane and is enhanced by lipid phase separation. By imaging the ionic flux through individual pores in vitro, we observe that EqtII pores form predominantly within the liquid-disordered phase. We observe preferential binding of labeled EqtII at liquid-ordered/liquid-disordered domain boundaries before it accumulates in the liquid-disordered phase." @default.
- W2021551854 created "2016-06-24" @default.
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- W2021551854 date "2014-04-01" @default.
- W2021551854 modified "2023-10-16" @default.
- W2021551854 title "Imaging the Lipid-Phase-Dependent Pore Formation of Equinatoxin II in Droplet Interface Bilayers" @default.
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- W2021551854 doi "https://doi.org/10.1016/j.bpj.2013.11.4507" @default.
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