Matches in SemOpenAlex for { <https://semopenalex.org/work/W2021569156> ?p ?o ?g. }
Showing items 1 to 75 of
75
with 100 items per page.
- W2021569156 endingPage "180" @default.
- W2021569156 startingPage "175" @default.
- W2021569156 abstract "Splenic nerve stimulation (10 Hz for 2 min) caused a perfusion-pressure increase, a volume reduction and an increase in the output of neuropeptide Y-like immunoreactivity (NPY-LI) from the isolated blood-perfused cat spleen. Gel-filtration HPLC analysis revealed that plasma NPY-LI collected during nerve stimulation was similar to the NPY-LI in the spleen and synthetic porcine NPY. Combined propranolol and phenoxybenzamine pretreatment enhanced NPY output upon nerve stimulation by about 60%. Forty percent of the perfusion-pressure increase and 25% of the volume reduction seen during control stimulations remained after adrenoceptor blockade. Guanethidine abolished the release of NPY-LI, the perfusion-pressure increase and the volume reduction normally seen upon splenic nerve stimulation. Infusion of synthetic porcine NPY caused a long-lasting increase in perfusion pressure and a relatively moderate volume reduction. Noradrenaline (NA) both increased perfusion pressure and induced a marked volume reduction. The NPY effects were resistant to adrenoceptor antagonists in doses which abolished the NA response. In conclusion, the present data show that NPY-LI is released upon sympathetic nerve stimulation by a guanethidine-sensitive mechanism. Furthermore, the sympathetic response is partially resistant to adrenoceptor antagonists and NPY has powerful vasoconstrictor effects. This provides further evidence for a role of NPY in sympathetic vascular control." @default.
- W2021569156 created "2016-06-24" @default.
- W2021569156 creator A5009029354 @default.
- W2021569156 creator A5013543425 @default.
- W2021569156 creator A5015484353 @default.
- W2021569156 creator A5050380848 @default.
- W2021569156 date "1984-11-01" @default.
- W2021569156 modified "2023-10-12" @default.
- W2021569156 title "Guanethidine-sensitive release of neuropeptide Y-like immunoreactivity in the cat spleen by sympathetic nerve stimulation" @default.
- W2021569156 cites W1984909793 @default.
- W2021569156 cites W2007903907 @default.
- W2021569156 cites W2040936125 @default.
- W2021569156 cites W2052173587 @default.
- W2021569156 cites W2071574435 @default.
- W2021569156 cites W2098321969 @default.
- W2021569156 cites W2125076183 @default.
- W2021569156 cites W2162210200 @default.
- W2021569156 doi "https://doi.org/10.1016/0304-3940(84)90370-7" @default.
- W2021569156 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/6098874" @default.
- W2021569156 hasPublicationYear "1984" @default.
- W2021569156 type Work @default.
- W2021569156 sameAs 2021569156 @default.
- W2021569156 citedByCount "190" @default.
- W2021569156 countsByYear W20215691562018 @default.
- W2021569156 crossrefType "journal-article" @default.
- W2021569156 hasAuthorship W2021569156A5009029354 @default.
- W2021569156 hasAuthorship W2021569156A5013543425 @default.
- W2021569156 hasAuthorship W2021569156A5015484353 @default.
- W2021569156 hasAuthorship W2021569156A5050380848 @default.
- W2021569156 hasConcept C118303440 @default.
- W2021569156 hasConcept C126322002 @default.
- W2021569156 hasConcept C134018914 @default.
- W2021569156 hasConcept C146957229 @default.
- W2021569156 hasConcept C170493617 @default.
- W2021569156 hasConcept C185592680 @default.
- W2021569156 hasConcept C24998067 @default.
- W2021569156 hasConcept C2776232365 @default.
- W2021569156 hasConcept C2776533406 @default.
- W2021569156 hasConcept C71924100 @default.
- W2021569156 hasConcept C84393581 @default.
- W2021569156 hasConcept C93984277 @default.
- W2021569156 hasConceptScore W2021569156C118303440 @default.
- W2021569156 hasConceptScore W2021569156C126322002 @default.
- W2021569156 hasConceptScore W2021569156C134018914 @default.
- W2021569156 hasConceptScore W2021569156C146957229 @default.
- W2021569156 hasConceptScore W2021569156C170493617 @default.
- W2021569156 hasConceptScore W2021569156C185592680 @default.
- W2021569156 hasConceptScore W2021569156C24998067 @default.
- W2021569156 hasConceptScore W2021569156C2776232365 @default.
- W2021569156 hasConceptScore W2021569156C2776533406 @default.
- W2021569156 hasConceptScore W2021569156C71924100 @default.
- W2021569156 hasConceptScore W2021569156C84393581 @default.
- W2021569156 hasConceptScore W2021569156C93984277 @default.
- W2021569156 hasIssue "1-2" @default.
- W2021569156 hasLocation W20215691561 @default.
- W2021569156 hasLocation W20215691562 @default.
- W2021569156 hasOpenAccess W2021569156 @default.
- W2021569156 hasPrimaryLocation W20215691561 @default.
- W2021569156 hasRelatedWork W1968401882 @default.
- W2021569156 hasRelatedWork W1974809200 @default.
- W2021569156 hasRelatedWork W1978189837 @default.
- W2021569156 hasRelatedWork W2000776761 @default.
- W2021569156 hasRelatedWork W2008849257 @default.
- W2021569156 hasRelatedWork W2022706695 @default.
- W2021569156 hasRelatedWork W2048619843 @default.
- W2021569156 hasRelatedWork W2138733863 @default.
- W2021569156 hasRelatedWork W2147062559 @default.
- W2021569156 hasRelatedWork W2324925659 @default.
- W2021569156 hasVolume "52" @default.
- W2021569156 isParatext "false" @default.
- W2021569156 isRetracted "false" @default.
- W2021569156 magId "2021569156" @default.
- W2021569156 workType "article" @default.