Matches in SemOpenAlex for { <https://semopenalex.org/work/W2021576788> ?p ?o ?g. }
Showing items 1 to 97 of
97
with 100 items per page.
- W2021576788 endingPage "619" @default.
- W2021576788 startingPage "616" @default.
- W2021576788 abstract "Light activates rod outer segment (ROS) phosphodiesterase (PDEase), as shown by previous biochemical and physiological studies. We have further investigated the role of PDEase in this system by injecting trypsin-activated PDEase, purified from bovine ROS, into single ROS of the isolated retina of the toad Bufo marinus. Injection of about 300 molecules of activated PDEase in darkness is without immediate detectable effect, as measured by intracellular membrane-voltage recording. The effect of the activated PDEase injections only becomes evident after illumination. The light response is augmented; kinetics of repolarization are slowed. We conclude that this augmentation of the light-dependent hyperpolarization results from the hydrolysis of endogenous cyclic GMP caused by injected PDEase. These results provide evidence that PDEase affects light-dependent channels of the vertebrate scotopic photoreceptors but do not specify whether the effects are exercised for the initial hyperpolarizing phase of the receptor potential and for the recovery phase or only for the recovery phase." @default.
- W2021576788 created "2016-06-24" @default.
- W2021576788 creator A5027551170 @default.
- W2021576788 creator A5038005055 @default.
- W2021576788 creator A5045343664 @default.
- W2021576788 date "1984-01-01" @default.
- W2021576788 modified "2023-09-23" @default.
- W2021576788 title "Rod light response augmented by active phosphodiesterase." @default.
- W2021576788 cites W111988334 @default.
- W2021576788 cites W1570762629 @default.
- W2021576788 cites W1964548100 @default.
- W2021576788 cites W1968726533 @default.
- W2021576788 cites W1971057798 @default.
- W2021576788 cites W1982546453 @default.
- W2021576788 cites W2030482250 @default.
- W2021576788 cites W2039673340 @default.
- W2021576788 cites W2046298808 @default.
- W2021576788 cites W2049605341 @default.
- W2021576788 cites W2096372807 @default.
- W2021576788 cites W2140339686 @default.
- W2021576788 doi "https://doi.org/10.1073/pnas.81.2.616" @default.
- W2021576788 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/344730" @default.
- W2021576788 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/6320200" @default.
- W2021576788 hasPublicationYear "1984" @default.
- W2021576788 type Work @default.
- W2021576788 sameAs 2021576788 @default.
- W2021576788 citedByCount "5" @default.
- W2021576788 crossrefType "journal-article" @default.
- W2021576788 hasAuthorship W2021576788A5027551170 @default.
- W2021576788 hasAuthorship W2021576788A5038005055 @default.
- W2021576788 hasAuthorship W2021576788A5045343664 @default.
- W2021576788 hasBestOaLocation W20215767882 @default.
- W2021576788 hasConcept C12554922 @default.
- W2021576788 hasConcept C131453863 @default.
- W2021576788 hasConcept C131667965 @default.
- W2021576788 hasConcept C134018914 @default.
- W2021576788 hasConcept C16613235 @default.
- W2021576788 hasConcept C169760540 @default.
- W2021576788 hasConcept C178790620 @default.
- W2021576788 hasConcept C181199279 @default.
- W2021576788 hasConcept C181911157 @default.
- W2021576788 hasConcept C185592680 @default.
- W2021576788 hasConcept C2777093970 @default.
- W2021576788 hasConcept C2778166480 @default.
- W2021576788 hasConcept C2779027399 @default.
- W2021576788 hasConcept C55493867 @default.
- W2021576788 hasConcept C59822182 @default.
- W2021576788 hasConcept C62826618 @default.
- W2021576788 hasConcept C66974803 @default.
- W2021576788 hasConcept C79879829 @default.
- W2021576788 hasConcept C86803240 @default.
- W2021576788 hasConcept C95444343 @default.
- W2021576788 hasConceptScore W2021576788C12554922 @default.
- W2021576788 hasConceptScore W2021576788C131453863 @default.
- W2021576788 hasConceptScore W2021576788C131667965 @default.
- W2021576788 hasConceptScore W2021576788C134018914 @default.
- W2021576788 hasConceptScore W2021576788C16613235 @default.
- W2021576788 hasConceptScore W2021576788C169760540 @default.
- W2021576788 hasConceptScore W2021576788C178790620 @default.
- W2021576788 hasConceptScore W2021576788C181199279 @default.
- W2021576788 hasConceptScore W2021576788C181911157 @default.
- W2021576788 hasConceptScore W2021576788C185592680 @default.
- W2021576788 hasConceptScore W2021576788C2777093970 @default.
- W2021576788 hasConceptScore W2021576788C2778166480 @default.
- W2021576788 hasConceptScore W2021576788C2779027399 @default.
- W2021576788 hasConceptScore W2021576788C55493867 @default.
- W2021576788 hasConceptScore W2021576788C59822182 @default.
- W2021576788 hasConceptScore W2021576788C62826618 @default.
- W2021576788 hasConceptScore W2021576788C66974803 @default.
- W2021576788 hasConceptScore W2021576788C79879829 @default.
- W2021576788 hasConceptScore W2021576788C86803240 @default.
- W2021576788 hasConceptScore W2021576788C95444343 @default.
- W2021576788 hasIssue "2" @default.
- W2021576788 hasLocation W20215767881 @default.
- W2021576788 hasLocation W20215767882 @default.
- W2021576788 hasLocation W20215767883 @default.
- W2021576788 hasLocation W20215767884 @default.
- W2021576788 hasLocation W20215767885 @default.
- W2021576788 hasOpenAccess W2021576788 @default.
- W2021576788 hasPrimaryLocation W20215767881 @default.
- W2021576788 hasRelatedWork W129948102 @default.
- W2021576788 hasRelatedWork W1550563000 @default.
- W2021576788 hasRelatedWork W2017146501 @default.
- W2021576788 hasRelatedWork W2054867060 @default.
- W2021576788 hasRelatedWork W2063203362 @default.
- W2021576788 hasRelatedWork W2096372807 @default.
- W2021576788 hasRelatedWork W2135452620 @default.
- W2021576788 hasRelatedWork W2171496211 @default.
- W2021576788 hasRelatedWork W2411060286 @default.
- W2021576788 hasRelatedWork W2427039831 @default.
- W2021576788 hasVolume "81" @default.
- W2021576788 isParatext "false" @default.
- W2021576788 isRetracted "false" @default.
- W2021576788 magId "2021576788" @default.
- W2021576788 workType "article" @default.