FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2021582397> ?p ?o ?g. }

• W2021582397 endingPage "2008" @default.
• W2021582397 startingPage "2003" @default.
• W2021582397 abstract "DJ-1, a novel mitogen-dependent oncogene, has an important role in the progression of human malignancies, whereas tumor suppressor phosphatase and tensin homolog (PTEN) is known to control a variety of processes associated with cell survival, proliferation and invasion. DJ‑1 overexpression was reported to be negatively correlated with PTEN expression in tumor tissues of patients with laryngeal squamous cell carcinoma (LSCC). In the present study, the effect of DJ‑1 on PTEN in laryngeal cancer cells was investigated by transfecting DJ‑1‑specific small interfering (si)RNA into Hep‑2 and SNU‑899 cells. Cell survival and cell proliferative and invasive capacity were then evaluated. The results showed that siRNA targeting of DJ‑1 effectively upregulated PTEN expression, resulting in enhanced cell death as well as decreased proliferation and invasion of Hep‑2 and SNU‑899 cells. The results of the present study indicated, for the first time, to the best of our knowledge, that DJ‑1‑induced PTEN downregulation is associated with proliferative and invasive activity of laryngeal cancer cells. The DJ-1 gene may have an important role in the tumorigenesis of LSCC." @default.
• W2021582397 created "2016-06-24" @default.
• W2021582397 creator A5004296782 @default.
• W2021582397 creator A5015204786 @default.
• W2021582397 creator A5066209383 @default.
• W2021582397 creator A5066540076 @default.
• W2021582397 creator A5074521429 @default.
• W2021582397 creator A5077362015 @default.
• W2021582397 date "2015-04-15" @default.
• W2021582397 modified "2023-10-16" @default.
• W2021582397 title "DJ-1-induced phosphatase and tensin homologue downregulation is associated with proliferative and invasive activity of laryngeal cancer cells" @default.
• W2021582397 cites W1556838263 @default.
• W2021582397 cites W1990847293 @default.
• W2021582397 cites W1998704092 @default.
• W2021582397 cites W2009127180 @default.
• W2021582397 cites W2022215347 @default.
• W2021582397 cites W2024801074 @default.
• W2021582397 cites W2029854095 @default.
• W2021582397 cites W2047964417 @default.
• W2021582397 cites W2059209321 @default.
• W2021582397 cites W2064810566 @default.
• W2021582397 cites W2070766926 @default.
• W2021582397 cites W2078312014 @default.
• W2021582397 cites W2087832022 @default.
• W2021582397 cites W2096291986 @default.
• W2021582397 cites W2117462796 @default.
• W2021582397 cites W2118621169 @default.
• W2021582397 cites W2129764664 @default.
• W2021582397 cites W2130397713 @default.
• W2021582397 cites W2138038992 @default.
• W2021582397 cites W2151876242 @default.
• W2021582397 cites W2169453618 @default.
• W2021582397 cites W2169823449 @default.
• W2021582397 doi "https://doi.org/10.3892/mmr.2015.3617" @default.
• W2021582397 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25892179" @default.
• W2021582397 hasPublicationYear "2015" @default.
• W2021582397 type Work @default.
• W2021582397 sameAs 2021582397 @default.
• W2021582397 citedByCount "5" @default.
• W2021582397 countsByYear W20215823972016 @default.
• W2021582397 countsByYear W20215823972018 @default.
• W2021582397 countsByYear W20215823972020 @default.
• W2021582397 countsByYear W20215823972021 @default.
• W2021582397 crossrefType "journal-article" @default.
• W2021582397 hasAuthorship W2021582397A5004296782 @default.
• W2021582397 hasAuthorship W2021582397A5015204786 @default.
• W2021582397 hasAuthorship W2021582397A5066209383 @default.
• W2021582397 hasAuthorship W2021582397A5066540076 @default.
• W2021582397 hasAuthorship W2021582397A5074521429 @default.
• W2021582397 hasAuthorship W2021582397A5077362015 @default.
• W2021582397 hasBestOaLocation W20215823971 @default.
• W2021582397 hasConcept C104317684 @default.
• W2021582397 hasConcept C121608353 @default.
• W2021582397 hasConcept C127561419 @default.
• W2021582397 hasConcept C1491633281 @default.
• W2021582397 hasConcept C2777609662 @default.
• W2021582397 hasConcept C2778264664 @default.
• W2021582397 hasConcept C2779549131 @default.
• W2021582397 hasConcept C2781018059 @default.
• W2021582397 hasConcept C29537977 @default.
• W2021582397 hasConcept C502942594 @default.
• W2021582397 hasConcept C54355233 @default.
• W2021582397 hasConcept C55493867 @default.
• W2021582397 hasConcept C555283112 @default.
• W2021582397 hasConcept C62112901 @default.
• W2021582397 hasConcept C62478195 @default.
• W2021582397 hasConcept C86554907 @default.
• W2021582397 hasConcept C86803240 @default.
• W2021582397 hasConcept C95444343 @default.
• W2021582397 hasConceptScore W2021582397C104317684 @default.
• W2021582397 hasConceptScore W2021582397C121608353 @default.
• W2021582397 hasConceptScore W2021582397C127561419 @default.
• W2021582397 hasConceptScore W2021582397C1491633281 @default.
• W2021582397 hasConceptScore W2021582397C2777609662 @default.
• W2021582397 hasConceptScore W2021582397C2778264664 @default.
• W2021582397 hasConceptScore W2021582397C2779549131 @default.
• W2021582397 hasConceptScore W2021582397C2781018059 @default.
• W2021582397 hasConceptScore W2021582397C29537977 @default.
• W2021582397 hasConceptScore W2021582397C502942594 @default.
• W2021582397 hasConceptScore W2021582397C54355233 @default.
• W2021582397 hasConceptScore W2021582397C55493867 @default.
• W2021582397 hasConceptScore W2021582397C555283112 @default.
• W2021582397 hasConceptScore W2021582397C62112901 @default.
• W2021582397 hasConceptScore W2021582397C62478195 @default.
• W2021582397 hasConceptScore W2021582397C86554907 @default.
• W2021582397 hasConceptScore W2021582397C86803240 @default.
• W2021582397 hasConceptScore W2021582397C95444343 @default.
• W2021582397 hasIssue "2" @default.
• W2021582397 hasLocation W20215823971 @default.
• W2021582397 hasLocation W20215823972 @default.
• W2021582397 hasOpenAccess W2021582397 @default.
• W2021582397 hasPrimaryLocation W20215823971 @default.
• W2021582397 hasRelatedWork W2021582397 @default.
• W2021582397 hasRelatedWork W2031690321 @default.
• W2021582397 hasRelatedWork W2117441185 @default.
• W2021582397 hasRelatedWork W2150002449 @default.
• W2021582397 hasRelatedWork W2318370472 @default.
• W2021582397 hasRelatedWork W2543495975 @default.

• next