FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2021616811> ?p ?o ?g. }

• W2021616811 endingPage "257" @default.
• W2021616811 startingPage "249" @default.
• W2021616811 abstract "We have previously demonstrated in a pilot study of 348 invasive breast cancers that mast cell (MC) infiltrates within primary breast cancers are associated with a good prognosis. Our aim was to verify this finding in a larger cohort of invasive breast cancer patients and examine the relationship between the presence of MCs and other clinical and pathological features. Clinically annotated tissue microarrays (TMAs) containing 4,444 cases were constructed and stained with c-Kit (CD-117) using standard immunoperoxidase techniques to identify and quantify MCs. For statistical analysis, we applied a split-sample validation technique. Breast cancer specific survival was analyzed by Kaplan–Meier [KM] method and log rank test was used to compare survival curves. Survival analysis by KM method showed that the presence of stromal MCs was a favourable prognostic factor in the training set (P = 0.001), and the validation set group (P = 0.006). X-tile plot generated to define the optimal number of MCs showed that the presence of any number of stromal MCs predicted good prognosis. Multivariate analysis showed that the MC effect in the training set (Hazard ratio [HR] = 0.804, 95% Confidence interval [CI], 0.653–0.991, P = 0.041) and validation set analysis (HR = 0.846, 95% CI, 0.683–1.049, P = 0.128) was independent of age, tumor grade, tumor size, lymph node, ER and Her2 status. This study concludes that stromal MC infiltration in invasive breast cancer is an independent good prognostic marker and reiterates the critical role of local inflammatory responses in breast cancer progression." @default.
• W2021616811 created "2016-06-24" @default.
• W2021616811 creator A5015644283 @default.
• W2021616811 creator A5019349196 @default.
• W2021616811 creator A5034748924 @default.
• W2021616811 creator A5046749955 @default.
• W2021616811 creator A5067468792 @default.
• W2021616811 creator A5076031555 @default.
• W2021616811 creator A5080336952 @default.
• W2021616811 creator A5085086748 @default.
• W2021616811 date "2007-03-13" @default.
• W2021616811 modified "2023-10-17" @default.
• W2021616811 title "Stromal mast cells in invasive breast cancer are a marker of favourable prognosis: a study of 4,444 cases" @default.
• W2021616811 cites W1480357432 @default.
• W2021616811 cites W1560466618 @default.
• W2021616811 cites W1606413143 @default.
• W2021616811 cites W1969267175 @default.
• W2021616811 cites W1980257335 @default.
• W2021616811 cites W1983562760 @default.
• W2021616811 cites W1986105643 @default.
• W2021616811 cites W1991691263 @default.
• W2021616811 cites W199712806 @default.
• W2021616811 cites W2004329227 @default.
• W2021616811 cites W2024813393 @default.
• W2021616811 cites W2029389633 @default.
• W2021616811 cites W2034978601 @default.
• W2021616811 cites W2041669185 @default.
• W2021616811 cites W2046803689 @default.
• W2021616811 cites W2051883426 @default.
• W2021616811 cites W2053265457 @default.
• W2021616811 cites W2055585136 @default.
• W2021616811 cites W2058650411 @default.
• W2021616811 cites W2061316941 @default.
• W2021616811 cites W2072315546 @default.
• W2021616811 cites W2074226517 @default.
• W2021616811 cites W2083006984 @default.
• W2021616811 cites W2083839175 @default.
• W2021616811 cites W2090488685 @default.
• W2021616811 cites W2097977223 @default.
• W2021616811 cites W2100021275 @default.
• W2021616811 cites W2100272405 @default.
• W2021616811 cites W2133650808 @default.
• W2021616811 cites W2134013972 @default.
• W2021616811 cites W2134632882 @default.
• W2021616811 cites W2138163780 @default.
• W2021616811 cites W2142300779 @default.
• W2021616811 cites W2147087574 @default.
• W2021616811 cites W2150657589 @default.
• W2021616811 cites W2150678612 @default.
• W2021616811 cites W2153188790 @default.
• W2021616811 cites W2163726013 @default.
• W2021616811 cites W2164260706 @default.
• W2021616811 cites W2168658644 @default.
• W2021616811 cites W2256056742 @default.
• W2021616811 cites W2420847704 @default.
• W2021616811 doi "https://doi.org/10.1007/s10549-007-9546-3" @default.
• W2021616811 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2137942" @default.
• W2021616811 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/17431762" @default.
• W2021616811 hasPublicationYear "2007" @default.
• W2021616811 type Work @default.
• W2021616811 sameAs 2021616811 @default.
• W2021616811 citedByCount "174" @default.
• W2021616811 countsByYear W20216168112012 @default.
• W2021616811 countsByYear W20216168112013 @default.
• W2021616811 countsByYear W20216168112014 @default.
• W2021616811 countsByYear W20216168112015 @default.
• W2021616811 countsByYear W20216168112016 @default.
• W2021616811 countsByYear W20216168112017 @default.
• W2021616811 countsByYear W20216168112018 @default.
• W2021616811 countsByYear W20216168112019 @default.
• W2021616811 countsByYear W20216168112020 @default.
• W2021616811 countsByYear W20216168112021 @default.
• W2021616811 countsByYear W20216168112022 @default.
• W2021616811 countsByYear W20216168112023 @default.
• W2021616811 crossrefType "journal-article" @default.
• W2021616811 hasAuthorship W2021616811A5015644283 @default.
• W2021616811 hasAuthorship W2021616811A5019349196 @default.
• W2021616811 hasAuthorship W2021616811A5034748924 @default.
• W2021616811 hasAuthorship W2021616811A5046749955 @default.
• W2021616811 hasAuthorship W2021616811A5067468792 @default.
• W2021616811 hasAuthorship W2021616811A5076031555 @default.
• W2021616811 hasAuthorship W2021616811A5080336952 @default.
• W2021616811 hasAuthorship W2021616811A5085086748 @default.
• W2021616811 hasBestOaLocation W20216168111 @default.
• W2021616811 hasConcept C10515644 @default.
• W2021616811 hasConcept C121608353 @default.
• W2021616811 hasConcept C126322002 @default.
• W2021616811 hasConcept C142724271 @default.
• W2021616811 hasConcept C143998085 @default.
• W2021616811 hasConcept C16930146 @default.
• W2021616811 hasConcept C193270364 @default.
• W2021616811 hasConcept C207103383 @default.
• W2021616811 hasConcept C2780849966 @default.
• W2021616811 hasConcept C44249647 @default.
• W2021616811 hasConcept C530470458 @default.
• W2021616811 hasConcept C71924100 @default.
• W2021616811 hasConceptScore W2021616811C10515644 @default.
• W2021616811 hasConceptScore W2021616811C121608353 @default.

• next