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- W2021618722 abstract "Abstract Analogs of thymidine-5′-monophosphate, thymidine-5′-monophosphate- p -nitrophenylester, and adenosine-5′-monophosphate with an amino or azido group in the 3′-position have been synthesized by convenient methods. These compounds were tested as substrates for acid phosphatase from potatoes (EC 3.1.3.27), 5′-nucleotidase from snake venom (EC 3.1.3.5), alkaline phosphatase from calf intestine (EC 3.1.3.1), and phosphodiesterase from snake venom (EC 3.1.4.1). The influence of the modification was found to increase with the higher specificity of the enzymes (thus, e.g., 5′-nucleotidase does not accept the 3′-modified thymidine derivatives)." @default.
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- W2021618722 date "1978-03-01" @default.
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- W2021618722 title "3′-modified nucleotides: Substrate recognition by phosphohydrolases" @default.
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