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• W2021622275 abstract "Pepducins are a class of lipidated peptide G-protein coupled receptor (GPCR) allosteric modulators that exhibit unique pharmacological properties. Because of their rational design, pepducins can potentially be used to target all members of this gene family. In addition to enormous therapeutic potential, pepducins are proving to be valuable tools to elucidate the molecular mechanisms involved in GPCR signaling. In this review, we focus on the characterization of pepducin biology and discuss their utility as novel therapeutics." @default.
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• W2021622275 date "2012-03-01" @default.
• W2021622275 modified "2023-09-24" @default.
• W2021622275 title "Pepducins: lipopeptide allosteric modulators of GPCR signaling" @default.
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• W2021622275 doi "https://doi.org/10.1016/j.ddtec.2011.07.002" @default.
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