FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2021635331> ?p ?o ?g. }

• W2021635331 endingPage "472" @default.
• W2021635331 startingPage "462" @default.
• W2021635331 abstract "Macrophages and dendritic cells (DCs) are antigen-presenting cells (APCs), and the direct involvement of both cell types in the immune response to Salmonella has been identified. In this study we analysed the phenotypic and functional changes that take place in murine macrophages and DCs in response to live and heat-killed Salmonella enterica serovar Typhimurium. Both types of cell secreted proinflammatory cytokines and nitric oxide (NO) in response to live and heat-killed salmonellae. Bacterial stimulation also resulted in up-regulation of costimulatory molecules on macrophages and DCs. The expression of major histocompatibility complex (MHC) class II molecules by macrophages and DCs was differentially regulated by interferon (IFN)-gamma and salmonellae. Live and heat-killed salmonellae as well as lipopolysaccharide (LPS) inhibited the up-regulation of MHC class II expression induced by IFN-gamma on macrophages but not on DCs. Macrophages as well as DCs presented Salmonella-derived antigen to CD4 T cells, although DCs were much more efficient than macrophages at stimulating CD4 T-cell cytokine release. Macrophages are effective in the uptake and killing of bacteria whilst DCs specialize in antigen presentation. This study showed that the viability of salmonellae was not essential for activation of APCs but, unlike live bacteria, prolonged contact with heat-killed bacteria was necessary to obtain maximal expression of the activation markers studied." @default.
• W2021635331 created "2016-06-24" @default.
• W2021635331 creator A5059622534 @default.
• W2021635331 creator A5063395363 @default.
• W2021635331 creator A5070935391 @default.
• W2021635331 creator A5082137730 @default.
• W2021635331 date "2005-05-18" @default.
• W2021635331 modified "2023-10-15" @default.
• W2021635331 title "Activation of murine dendritic cells and macrophages induced by Salmonella enterica serovar Typhimurium" @default.
• W2021635331 cites W1479674079 @default.
• W2021635331 cites W1574316486 @default.
• W2021635331 cites W1612465238 @default.
• W2021635331 cites W1661544713 @default.
• W2021635331 cites W1663568315 @default.
• W2021635331 cites W1804793662 @default.
• W2021635331 cites W1833044145 @default.
• W2021635331 cites W1891269033 @default.
• W2021635331 cites W1958745508 @default.
• W2021635331 cites W1967203548 @default.
• W2021635331 cites W1976314544 @default.
• W2021635331 cites W1976907957 @default.
• W2021635331 cites W1979432835 @default.
• W2021635331 cites W1980625714 @default.
• W2021635331 cites W1981521326 @default.
• W2021635331 cites W1986557819 @default.
• W2021635331 cites W1989808086 @default.
• W2021635331 cites W1990802251 @default.
• W2021635331 cites W1997257161 @default.
• W2021635331 cites W1998092163 @default.
• W2021635331 cites W1998157460 @default.
• W2021635331 cites W2007107629 @default.
• W2021635331 cites W2013590443 @default.
• W2021635331 cites W2022973938 @default.
• W2021635331 cites W2027106756 @default.
• W2021635331 cites W2030865145 @default.
• W2021635331 cites W2032078625 @default.
• W2021635331 cites W2042048278 @default.
• W2021635331 cites W2054019820 @default.
• W2021635331 cites W2074528554 @default.
• W2021635331 cites W2077788018 @default.
• W2021635331 cites W2078864052 @default.
• W2021635331 cites W2078890331 @default.
• W2021635331 cites W2080097192 @default.
• W2021635331 cites W2084159211 @default.
• W2021635331 cites W2085198912 @default.
• W2021635331 cites W2092128665 @default.
• W2021635331 cites W2095225060 @default.
• W2021635331 cites W2100851332 @default.
• W2021635331 cites W2102119767 @default.
• W2021635331 cites W2102601193 @default.
• W2021635331 cites W2104327761 @default.
• W2021635331 cites W2111176922 @default.
• W2021635331 cites W2111695773 @default.
• W2021635331 cites W2112643590 @default.
• W2021635331 cites W2113120391 @default.
• W2021635331 cites W2115267868 @default.
• W2021635331 cites W2115632484 @default.
• W2021635331 cites W2116368319 @default.
• W2021635331 cites W2120046045 @default.
• W2021635331 cites W2125942132 @default.
• W2021635331 cites W2126245681 @default.
• W2021635331 cites W2131383434 @default.
• W2021635331 cites W2132650423 @default.
• W2021635331 cites W2137279806 @default.
• W2021635331 cites W2139202421 @default.
• W2021635331 cites W2139620037 @default.
• W2021635331 cites W2145949638 @default.
• W2021635331 cites W2150201696 @default.
• W2021635331 cites W2153841118 @default.
• W2021635331 cites W2161140777 @default.
• W2021635331 cites W2164381970 @default.
• W2021635331 cites W2164801366 @default.
• W2021635331 cites W2166938548 @default.
• W2021635331 cites W2171345725 @default.
• W2021635331 cites W2177327503 @default.
• W2021635331 cites W227594686 @default.
• W2021635331 cites W4236732267 @default.
• W2021635331 cites W4239384786 @default.
• W2021635331 doi "https://doi.org/10.1111/j.1365-2567.2005.02180.x" @default.
• W2021635331 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/1782185" @default.
• W2021635331 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16011515" @default.
• W2021635331 hasPublicationYear "2005" @default.
• W2021635331 type Work @default.
• W2021635331 sameAs 2021635331 @default.
• W2021635331 citedByCount "38" @default.
• W2021635331 countsByYear W20216353312013 @default.
• W2021635331 countsByYear W20216353312014 @default.
• W2021635331 countsByYear W20216353312015 @default.
• W2021635331 countsByYear W20216353312016 @default.
• W2021635331 countsByYear W20216353312018 @default.
• W2021635331 countsByYear W20216353312020 @default.
• W2021635331 countsByYear W20216353312021 @default.
• W2021635331 countsByYear W20216353312023 @default.
• W2021635331 crossrefType "journal-article" @default.
• W2021635331 hasAuthorship W2021635331A5059622534 @default.
• W2021635331 hasAuthorship W2021635331A5063395363 @default.
• W2021635331 hasAuthorship W2021635331A5070935391 @default.
• W2021635331 hasAuthorship W2021635331A5082137730 @default.

• next