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- W2021649968 abstract "Regional rat brain uptake of [18F]GBR 13119, a high specific activity, positron-emitter labeled derivative of the potent dopamine uptake antagonist GBR 12935, is reported. Striatum to cerebellum ratios of 3 are obtained at 90 minutes post injection. Specific binding in striatum can be blocked by pretreatment with dopamine uptake system antagonists (mazindol, nomifensine) but not with receptor antagonists (spiperone, flupenthixol). [18F]GBR 13119 is proposed as a new positron-emitting radioligand for in vivo PET studies of the pre-synaptic dopamine uptake system." @default.
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- W2021649968 title "In vivo binding of [18F]GBR 13119 to the brain dopamine uptake system" @default.
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- W2021649968 doi "https://doi.org/10.1016/0024-3205(88)90163-4" @default.
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