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• W2021654218 abstract "OBJECTIVE: To find out the prevalent phage groups of Staphylococcus aureus strains (S. Aureus), and find out their correlation with antibiotic resistance. MATERIALS AND METHODS: A total of 104 S. Aureus isolates were obtained from heterogenous clinical samples and their antimicrobial susceptibility was determined against 13 antibiotics by the Kirby Bauer disk diffusion method in accordance with the Clinical and Laboratory Standards Institute guidelines. They were phage typed by the international set of Staphylococcal phages at the National reference centre, Maulana Azad Medical College (MAM), New Delhi. RESULTS: Phage groups identified during this study period were III, NT, Mixed, II, and I in the order of 36, 34, 26, 5, and 3 (34.7, 32.7, 25 ,4.8, and 2.9 %) respectively. Based on resistance of S. aureus strains to cefoxitin, it was observed that 78(75%) of the S. aureus were MRSA and only 26 (25%) were MSSA. Analysis of Phage groups in relation to MRSA / MSSA revealed maximum number of MRSA 29 (37.18%) were non-typable. All the S. aureus strains (100%) were susceptible to vancomycin, linezolid, rifampicin, fusidic acid, clindamycin and teicoplanin. The resistance pattern of MRSA / MSSA to penicillin, oxacillin, doxycycline, erythromycin, gentamicin, co-trimoxazole, and ciprofloxacin were in the order of 98.7/ 96.2, 84.6/ 0, 21.8/11.5, 55.1/34.6, 51.3/ 7.7, 24.3/7.7, and 85.9/ 61.5% respectively. CONCLUSION: Using the international set of bacteriophages 67.3% of S. aureus strains were phage typed and the predominant phage group was III -84/47. Among MRSA 37.18% strains were non typable (NT). No strain was found in phage group V and non-allocated (NA). All tested isolates were sensitive to vancomycin, linezolid, rifampicin, fusidic acid, clindamycin and teicoplanin. When compared to MSSA strains, most of the MRSA strains were found to be resistant to commonly used antibiotics. Mixed group strains were significantly sensitive to gentamicin, penicillin and oxacillin (P<0.05). Phage group III strains were resistant to gentamicin when compared to strains of phage group I, II, Mixed." @default.
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• W2021654218 date "2013-07-18" @default.
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• W2021654218 title "STAPHYLOCOCCUS AUREUS PHAGE GROUPS AND THEIR RELATION TO ANTIBIOTIC RESISTANCE PATTERN IN A TERTIARY CARE HOSPITAL, SOUTH TAMIL NADU." @default.
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• W2021654218 doi "https://doi.org/10.14260/jemds/996" @default.
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