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- W2021658081 abstract "Model virus inactivation studies with lipid solvents were carried our in antihemophilic factor concentrates. The procoagulant activity obtained was >or=80% recovery with 20% amyl acetate-0.1% deoxycholate. A concurrent reduction of four logs of virus titer was obtained for model viruses provided the viral mass contained significant amounts (>or=20%) of lipid. From this preliminary study it appears that further investigations in animal models may be warranted to demonstrate the inactivation of hepatitis B virus, non-A-non-B virus, and AIDS virus with 20% amyl acetate-0.1% deoxycholate in antihemophilic factor concentrates." @default.
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- W2021658081 date "1986-02-01" @default.
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- W2021658081 title "Use of lipid solvents for viral inactivation in factor VIII concentrates" @default.
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- W2021658081 doi "https://doi.org/10.1002/bit.260280221" @default.
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