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- W2021693085 abstract "Since the beginning of the 20th century, concepts describing the ralationship between changes in peripheral (physiological) and central (psychological) parameters have changed dramatically. The classical notion that emotions were basically central projections of ‘visceral imbalances’ became overruled by the view that the Central Nervous System (CNS) plays and essential role in the control of peripheral physiological parameters and that emotions can actually cause ‘visceral imbalances’. This was demonstrated most elegantly by the finding of Cannon (Cannon & De la Paz 1911; Cannon 1914) that emotions elicited in a cat by exposing it to a barking dog, induce secretion of epinephrine from the adrenal medulla into the general circulation. Since then, evidence has accumulated demonstrating that not only sensory stimuli eliciting inborn or learned emotional reactions (e.g. anger, fear) but also physical or chemical disturbances of homeostasis (e.g. cold, high metabolic demands, blood loss, (endo)toxins, trauma) result in a concerted activation of the sympathetic nervous system and of chromaffin cells of the adrenal medulla (sympatho-adrenomedullary response). As a consequence, circulating levels of epinephrine (E) and norepinephrine (NE) rapidly increase following exposure of an individual to a systemic or psychological Stressor. These catecholamines in turn are responsible for a wide variety of cardiovascular, metabolic and other stress responses." @default.
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- W2021693085 date "1986-08-01" @default.
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- W2021693085 title "CRF and catecholamines; their place in the central and peripheral regulation of the stress response" @default.
- W2021693085 doi "https://doi.org/10.1530/acta.0.111s0063" @default.
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