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• W2021696269 abstract "Background Changes in service provision, secular trends in substance misuse and changing social structures might affect outcome in psychosis. Aims To assess the three-year outcome of an inception cohort of first-episode psychoses treated in a modern, community-oriented service; to compare outcomes with an earlier cohort treated in hospital-based care; and to examine the predictive validity of ICD–10 diagnostic criteria. Method Three-year follow-up (1995–1997) of an inception cohort of first-episode psychoses and comparison with two-year follow-up (1980–1982) of the Determinants of Outcome of Severe Mental Disorders (DOSMED) Nottingham cohort. Results On most outcome measures, non-affective psychoses had a worse outcome than affective psychoses. Affective psychoses had better outcome than previously reported. Substance-related psychoses had very poor occupational outcome. Similar proportions of the current and DOSMED cohort were in remission but the former were rated as having greater disability. Conclusions In a modern community service, 30–60% of patients with first-episode psychoses experience a good three-year outcome. The ICD–10 criteria have good predictive validity." @default.
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• W2021696269 date "2000-03-01" @default.
• W2021696269 modified "2023-10-10" @default.
• W2021696269 title "Three-year outcome of first-episode psychoses in an established community psychiatric service" @default.
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• W2021696269 doi "https://doi.org/10.1192/bjp.176.3.210" @default.
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