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- W2021737129 abstract "The binding of the D 1 antagonist SCH23390 to membrane preparations from rat cerebral cortex was examined using enantiomers of dopamine agonists and antagonists to compete with the bound [ 3 H]SCH23390 at its K d value. The competition curves were compared with those obtained with preparations from the neostriatum. The results demonstrate that specific [ 3 H]SCH23390 binding in the cerebral cortex has the same pharmacological profile as in the neostriatum, so that this radioligand can be used to label dopamine D 1 receptors in brain regions with a sparse dopaminergic innervation." @default.
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- W2021737129 date "1987-07-01" @default.
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- W2021737129 title "Stereospecific binding of a new benzazepine, [<sup>3</sup>H]SCH23390, in cortex and neostriatum" @default.
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- W2021737129 doi "https://doi.org/10.1139/y87-237" @default.
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