Matches in SemOpenAlex for { <https://semopenalex.org/work/W2021761625> ?p ?o ?g. }
Showing items 1 to 94 of
94
with 100 items per page.
- W2021761625 endingPage "536" @default.
- W2021761625 startingPage "529" @default.
- W2021761625 abstract "Administration of 10 micrograms of substance P intrathecally to the spinal T9 level of the adult rat, anaesthetized with urethane, provoked an increase in free catecholamines in plasma taken from the inferior vena cava. Adrenaline levels at 1 min after administration were 154.8 +/- 10.8% (mean +/- SE; n = 11) of preadministration levels and noradrenaline levels were 153.5 +/- 11.8% of preadministration levels. Differences between the values of free catecholamines in animals given substance P vs those given vehicle only were statistically significant at 1 and 10 min postinjection, but not at 30 min. Administration of a substance P analogue with central antagonistic properties 15 min before substance P was given prevented expression of the effects of substance P. These results suggest that substance P may be an excitatory chemical mediator of synaptic transmission in spinal pathways controlling adrenal medullary output. Thus dysfunction of substance P mechanisms may underlie some animal models of hypertension and may be involved in some cases of essential hypertension in man as well as in autonomic dysfunction associated with some neurological entities." @default.
- W2021761625 created "2016-06-24" @default.
- W2021761625 creator A5004968642 @default.
- W2021761625 creator A5035967610 @default.
- W2021761625 creator A5070982075 @default.
- W2021761625 date "1985-06-01" @default.
- W2021761625 modified "2023-10-16" @default.
- W2021761625 title "Substance P given intrathecally at the spinal T9 level increases adrenal output of adrenaline and noradrenaline in the rat" @default.
- W2021761625 cites W1966854255 @default.
- W2021761625 cites W1975575983 @default.
- W2021761625 cites W1976972192 @default.
- W2021761625 cites W1979729387 @default.
- W2021761625 cites W1998297127 @default.
- W2021761625 cites W2004456818 @default.
- W2021761625 cites W2011202256 @default.
- W2021761625 cites W2013690255 @default.
- W2021761625 cites W2019987584 @default.
- W2021761625 cites W2020602007 @default.
- W2021761625 cites W2022641758 @default.
- W2021761625 cites W2025528805 @default.
- W2021761625 cites W2040181384 @default.
- W2021761625 cites W2047876942 @default.
- W2021761625 cites W2068703281 @default.
- W2021761625 cites W2068934373 @default.
- W2021761625 cites W2071807048 @default.
- W2021761625 cites W2072664846 @default.
- W2021761625 cites W2077338927 @default.
- W2021761625 cites W2078497785 @default.
- W2021761625 cites W2085581222 @default.
- W2021761625 cites W2092990835 @default.
- W2021761625 cites W2323647611 @default.
- W2021761625 doi "https://doi.org/10.1016/0306-4522(85)90231-3" @default.
- W2021761625 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/2410814" @default.
- W2021761625 hasPublicationYear "1985" @default.
- W2021761625 type Work @default.
- W2021761625 sameAs 2021761625 @default.
- W2021761625 citedByCount "55" @default.
- W2021761625 countsByYear W20217616252023 @default.
- W2021761625 crossrefType "journal-article" @default.
- W2021761625 hasAuthorship W2021761625A5004968642 @default.
- W2021761625 hasAuthorship W2021761625A5035967610 @default.
- W2021761625 hasAuthorship W2021761625A5070982075 @default.
- W2021761625 hasConcept C118303440 @default.
- W2021761625 hasConcept C126322002 @default.
- W2021761625 hasConcept C134018914 @default.
- W2021761625 hasConcept C157820659 @default.
- W2021761625 hasConcept C170493617 @default.
- W2021761625 hasConcept C185592680 @default.
- W2021761625 hasConcept C2775859304 @default.
- W2021761625 hasConcept C2775894120 @default.
- W2021761625 hasConcept C2776533618 @default.
- W2021761625 hasConcept C2777597313 @default.
- W2021761625 hasConcept C2778514916 @default.
- W2021761625 hasConcept C42219234 @default.
- W2021761625 hasConcept C513476851 @default.
- W2021761625 hasConcept C71924100 @default.
- W2021761625 hasConcept C98274493 @default.
- W2021761625 hasConceptScore W2021761625C118303440 @default.
- W2021761625 hasConceptScore W2021761625C126322002 @default.
- W2021761625 hasConceptScore W2021761625C134018914 @default.
- W2021761625 hasConceptScore W2021761625C157820659 @default.
- W2021761625 hasConceptScore W2021761625C170493617 @default.
- W2021761625 hasConceptScore W2021761625C185592680 @default.
- W2021761625 hasConceptScore W2021761625C2775859304 @default.
- W2021761625 hasConceptScore W2021761625C2775894120 @default.
- W2021761625 hasConceptScore W2021761625C2776533618 @default.
- W2021761625 hasConceptScore W2021761625C2777597313 @default.
- W2021761625 hasConceptScore W2021761625C2778514916 @default.
- W2021761625 hasConceptScore W2021761625C42219234 @default.
- W2021761625 hasConceptScore W2021761625C513476851 @default.
- W2021761625 hasConceptScore W2021761625C71924100 @default.
- W2021761625 hasConceptScore W2021761625C98274493 @default.
- W2021761625 hasIssue "2" @default.
- W2021761625 hasLocation W20217616251 @default.
- W2021761625 hasLocation W20217616252 @default.
- W2021761625 hasOpenAccess W2021761625 @default.
- W2021761625 hasPrimaryLocation W20217616251 @default.
- W2021761625 hasRelatedWork W1978175539 @default.
- W2021761625 hasRelatedWork W1994862684 @default.
- W2021761625 hasRelatedWork W2024482129 @default.
- W2021761625 hasRelatedWork W2038512896 @default.
- W2021761625 hasRelatedWork W2044985824 @default.
- W2021761625 hasRelatedWork W2076974163 @default.
- W2021761625 hasRelatedWork W2079376440 @default.
- W2021761625 hasRelatedWork W2084281600 @default.
- W2021761625 hasRelatedWork W2097047907 @default.
- W2021761625 hasRelatedWork W2101285485 @default.
- W2021761625 hasVolume "15" @default.
- W2021761625 isParatext "false" @default.
- W2021761625 isRetracted "false" @default.
- W2021761625 magId "2021761625" @default.
- W2021761625 workType "article" @default.