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• W2021768581 abstract "No AccessJournal of UrologyAdult Urology1 May 2015Comparison of Baseline Urological Symptoms in Men and Women in the MAPP Research Cohort J. Quentin Clemens, Daniel J. Clauw, Karl Kreder, John N. Krieger, John W. Kusek, H. Henry Lai, Larissa Rodriguez, David A. Williams, Xiaoling Hou, Alisa Stephens, J. Richard Landis, and MAPP Research Network J. Quentin ClemensJ. Quentin Clemens University of Michigan Medical Center, Ann Arbor, Michigan More articles by this author , Daniel J. ClauwDaniel J. Clauw University of Michigan Medical Center, Ann Arbor, Michigan Financial interest and/or other relationship with Pfizer, Forest, Eli Lilly, Pierre Fabre, Cypress Bioscience, Wyeth, UCB, Astra Zeneca, Merck, J & J, Nuvo, Jazz, Abbott, Cerephex, Iroko, Tonix, Theravance, IMC, Zynerba and Samumed. More articles by this author , Karl KrederKarl Kreder University of Iowa, Iowa City, Iowa Financial interest and/or other relationship with Medtronic, Tengion and Symptelligence. More articles by this author , John N. KriegerJohn N. Krieger University of Washington, Seattle, Washington More articles by this author , John W. KusekJohn W. Kusek National Institute of Diabetes and Digestive and Kidney Diseases, Bethesda, Maryland More articles by this author , H. Henry LaiH. Henry Lai Washington University in St. Louis, St. Louis, Missouri Financial interest and/or other relationship with Medtronic. More articles by this author , Larissa RodriguezLarissa Rodriguez University of California Los Angeles, Los Angeles, California More articles by this author , David A. WilliamsDavid A. Williams University of Michigan Medical Center, Ann Arbor, Michigan Financial interest and/or other relationship with Health Focus. More articles by this author , Xiaoling HouXiaoling Hou University of Pennsylvania, Philadelphia, Pennsylvania More articles by this author , Alisa StephensAlisa Stephens University of Pennsylvania, Philadelphia, Pennsylvania More articles by this author , J. Richard LandisJ. Richard Landis University of Pennsylvania, Philadelphia, Pennsylvania More articles by this author , and MAPP Research Network More articles by this author View All Author Informationhttps://doi.org/10.1016/j.juro.2014.11.016AboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail Abstract Purpose: The clinical features of the interstitial cystitis/bladder pain syndrome are similar to those of the chronic prostatitis/chronic pelvic pain syndrome. However, to our knowledge no studies have directly compared the characteristics of these syndromes in men and women. Materials and Methods: The MAPP Research Network recruited 191 men and 233 women with IC/BPS or CP/CPPS. Baseline data included demographics, Interstitial Cystitis Symptom Index and Problem Index scores; Genitourinary Pain Index score; American Urological Association Symptom Index score; Likert scales to assess urinary urgency, frequency, pain and overall symptom severity; and a single question about the most bothersome pelvic symptom. Results: After adjustment for age, income and symptom duration, measures of pain severity were similar across genders. Mean scores for the ICSI, ICPI and AUASI were significantly higher in women than in men, reflecting more bladder focused symptoms in women. The most bothersome single symptom in men as well as in women was pain in the pubic/bladder area (men 34%, women 58%). The characteristics of the men and women in the MAPP cohort were similar to those reported in other research cohorts for IC/BPS and CP/CPPS. Conclusions: Our findings indicate that pain severity is similar for both genders and that bladder focused symptoms (urgency, suprapubic pain, frequency) are more common in women. However, a substantial proportion of men also reported these types of bladder symptoms. References 1 : Interstitial cystitis in the UK: results of a questionnaire survey of members of the Interstitial Cystitis Support Group. Eur J Obstet Gynecol Reprod Biol2005; 118: 91. Google Scholar 2 : What is the pain of interstitial cystitis like?. Int Urogynecol J2005; 17: 69. Google Scholar 3 : Prevalence and incidence of interstitial cystitis in a managed care population. J Urol2005; 173: 98. Link, Google Scholar 4 : The prevalence and overlap of interstitial cystitis/bladder pain syndrome and chronic prostatitis/chronic pelvic pain syndrome in men: results of the RAND Interstitial Cystitis Epidemiology male study. J Urol2013; 189: 141. 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Google Scholar © 2015 by American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetailsCited byNaliboff B, Schrepf A, Stephens-Shields A, Clemens J, Pontari M, Labus J, Taple B, Rodriguez L, Strachan E and Griffith J (2021) Temporal Relationships between Pain, Mood and Urinary Symptoms in Urological Chronic Pelvic Pain Syndrome: A MAPP Network StudyJournal of Urology, VOL. 205, NO. 6, (1698-1703), Online publication date: 1-Jun-2021.Clemens J, Stephens-Shields A, Newcomb C, Rodriguez L, Lai H, Bradley C, Naliboff B, Griffith J, Taple B, Gupta P, Afari N, Harte S, Strachan E, Guo W and Landis J (2020) Correlates of 1-Year Change in Quality of Life in Patients with Urologic Chronic Pelvic Pain Syndrome: Findings from the Multidisciplinary Approach to the Study of Chronic Pelvic Pain (MAPP) Research NetworkJournal of Urology, VOL. 204, NO. 4, (754-759), Online publication date: 1-Oct-2020.Lai H, Thu J, Moh F, Paradis A and Vetter J (2019) Clustering of Patients with Interstitial Cystitis/Bladder Pain Syndrome and Chronic Prostatitis/Chronic Pelvic Pain SyndromeJournal of Urology, VOL. 202, NO. 3, (546-551), Online publication date: 1-Sep-2019.Clemens J, Stephens-Shields A, Naliboff B, Lai H, Rodriguez L, Krieger J, Williams D, Kusek J and Landis J (2018) Correlates of Health Care Seeking Activities in Patients with Urological Chronic Pelvic Pain Syndromes: Findings from the MAPP CohortJournal of Urology, VOL. 200, NO. 1, (136-140), Online publication date: 1-Jul-2018.Naliboff B, Stephens A, Lai H, Griffith J, Clemens J, Lutgendorf S, Rodriguez L, Newcomb C, Sutcliffe S, Guo W, Kusek J and Landis J (2017) Clinical and Psychosocial Predictors of Urological Chronic Pelvic Pain Symptom Change in 1 Year: A Prospective Study from the MAPP Research NetworkJournal of Urology, VOL. 198, NO. 4, (848-857), Online publication date: 1-Oct-2017.Walker S, Zambon J, Andersson K, Langefeld C, Matthews C, Badlani G, Bowman H and Evans R (2017) Bladder Capacity is a Biomarker for a Bladder Centric versus Systemic Manifestation in Interstitial Cystitis/Bladder Pain SyndromeJournal of Urology, VOL. 198, NO. 2, (369-375), Online publication date: 1-Aug-2017.Nickel J, Egerdie B, Davis E, Evans R, Mackenzie L and Shrewsbury S (2016) A Phase II Study of the Efficacy and Safety of the Novel Oral SHIP1 Activator AQX-1125 in Subjects with Moderate to Severe Interstitial Cystitis/Bladder Pain SyndromeJournal of Urology, VOL. 196, NO. 3, (747-754), Online publication date: 1-Sep-2016.Kleinhans N, Yang C, Strachan E, Buchwald D and Maravilla K (2015) Alterations in Connectivity on Functional Magnetic Resonance Imaging with Provocation of Lower Urinary Tract Symptoms: A MAPP Research Network Feasibility Study of Urological Chronic Pelvic Pain SyndromesJournal of Urology, VOL. 195, NO. 3, (639-645), Online publication date: 1-Mar-2016.Steers W (2015) This Month in Adult UrologyJournal of Urology, VOL. 193, NO. 5, (1455-1456), Online publication date: 1-May-2015. Volume 193Issue 5May 2015Page: 1554-1558Supplementary Materials Advertisement Copyright & Permissions© 2015 by American Urological Association Education and Research, Inc.Keywordsinterstitialchronic paincystitisprostatitispelvic painMetricsAuthor Information J. Quentin Clemens University of Michigan Medical Center, Ann Arbor, Michigan More articles by this author Daniel J. Clauw University of Michigan Medical Center, Ann Arbor, Michigan Financial interest and/or other relationship with Pfizer, Forest, Eli Lilly, Pierre Fabre, Cypress Bioscience, Wyeth, UCB, Astra Zeneca, Merck, J & J, Nuvo, Jazz, Abbott, Cerephex, Iroko, Tonix, Theravance, IMC, Zynerba and Samumed. More articles by this author Karl Kreder University of Iowa, Iowa City, Iowa Financial interest and/or other relationship with Medtronic, Tengion and Symptelligence. More articles by this author John N. Krieger University of Washington, Seattle, Washington More articles by this author John W. Kusek National Institute of Diabetes and Digestive and Kidney Diseases, Bethesda, Maryland More articles by this author H. Henry Lai Washington University in St. Louis, St. Louis, Missouri Financial interest and/or other relationship with Medtronic. More articles by this author Larissa Rodriguez University of California Los Angeles, Los Angeles, California More articles by this author David A. Williams University of Michigan Medical Center, Ann Arbor, Michigan Financial interest and/or other relationship with Health Focus. More articles by this author Xiaoling Hou University of Pennsylvania, Philadelphia, Pennsylvania More articles by this author Alisa Stephens University of Pennsylvania, Philadelphia, Pennsylvania More articles by this author J. Richard Landis University of Pennsylvania, Philadelphia, Pennsylvania More articles by this author MAPP Research Network More articles by this author Expand All Advertisement PDF downloadLoading ..." @default.
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