Matches in SemOpenAlex for { <https://semopenalex.org/work/W2021791491> ?p ?o ?g. }
- W2021791491 endingPage "491" @default.
- W2021791491 startingPage "484" @default.
- W2021791491 abstract "In this study, the effects of heparin–superoxide dismutase conjugate (heparin–SOD) on bleomycin-induced pulmonary fibrosis in vivo and on inflammatory cytokine expression in vitro were evaluated. To investigate the effects of heparin–SOD on pulmonary fibrosis, heparin–SOD was administered to bleomycin (BLM)-treated mice by intraperitoneal injection once a day and the hydroxyproline content in lung was determined per 7 days. The degree of fibrosis was assessed quantitatively using histopathologic features. The results showed that heparin–SOD inhibited BLM-induced lung fibrotic lesions as reflected by the decrease of lung hydroxyproline content and lung fibrosis grade 28 days after BLM instillation. The in vitro effects on the cytokine level expressed by irradiated 3T3 fibroblasts showed that heparin–SOD significantly lowered the levels of transforming growth factor-β1 and interleukin-1β. These results strongly demonstrated that heparin–SOD might be useful in the prevention and treatment of pulmonary fibrosis." @default.
- W2021791491 created "2016-06-24" @default.
- W2021791491 creator A5007348590 @default.
- W2021791491 creator A5021871878 @default.
- W2021791491 creator A5023646928 @default.
- W2021791491 creator A5025878951 @default.
- W2021791491 creator A5066306425 @default.
- W2021791491 date "2009-08-01" @default.
- W2021791491 modified "2023-10-18" @default.
- W2021791491 title "Attenuation effects of heparin–superoxide dismutase conjugate on bleomycin-induced lung fibrosis in vivo and radiation-induced inflammatory cytokine expression in vitro" @default.
- W2021791491 cites W1879089985 @default.
- W2021791491 cites W1892178119 @default.
- W2021791491 cites W1904757281 @default.
- W2021791491 cites W1964830654 @default.
- W2021791491 cites W1973857971 @default.
- W2021791491 cites W1980921956 @default.
- W2021791491 cites W1982806380 @default.
- W2021791491 cites W1984428662 @default.
- W2021791491 cites W1989766796 @default.
- W2021791491 cites W1990584310 @default.
- W2021791491 cites W2003197058 @default.
- W2021791491 cites W2013114941 @default.
- W2021791491 cites W2019485706 @default.
- W2021791491 cites W2022219828 @default.
- W2021791491 cites W2023144855 @default.
- W2021791491 cites W2027913038 @default.
- W2021791491 cites W2030073835 @default.
- W2021791491 cites W2032393507 @default.
- W2021791491 cites W2034462747 @default.
- W2021791491 cites W2035540752 @default.
- W2021791491 cites W2043869065 @default.
- W2021791491 cites W2044004659 @default.
- W2021791491 cites W2044478331 @default.
- W2021791491 cites W2053630445 @default.
- W2021791491 cites W2055494379 @default.
- W2021791491 cites W2057955197 @default.
- W2021791491 cites W2059919089 @default.
- W2021791491 cites W2060701999 @default.
- W2021791491 cites W2063902734 @default.
- W2021791491 cites W2064820762 @default.
- W2021791491 cites W2065977597 @default.
- W2021791491 cites W2072993227 @default.
- W2021791491 cites W2074953718 @default.
- W2021791491 cites W2084168776 @default.
- W2021791491 cites W2085179127 @default.
- W2021791491 cites W2090959727 @default.
- W2021791491 cites W2093730650 @default.
- W2021791491 cites W2116369099 @default.
- W2021791491 cites W2118696428 @default.
- W2021791491 cites W2119341928 @default.
- W2021791491 cites W2128273234 @default.
- W2021791491 cites W2132878122 @default.
- W2021791491 cites W2143498239 @default.
- W2021791491 cites W2176384617 @default.
- W2021791491 cites W2320667912 @default.
- W2021791491 cites W2346410706 @default.
- W2021791491 cites W2380531090 @default.
- W2021791491 doi "https://doi.org/10.1016/j.biopha.2008.04.009" @default.
- W2021791491 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/18602243" @default.
- W2021791491 hasPublicationYear "2009" @default.
- W2021791491 type Work @default.
- W2021791491 sameAs 2021791491 @default.
- W2021791491 citedByCount "16" @default.
- W2021791491 countsByYear W20217914912012 @default.
- W2021791491 countsByYear W20217914912013 @default.
- W2021791491 countsByYear W20217914912014 @default.
- W2021791491 countsByYear W20217914912017 @default.
- W2021791491 countsByYear W20217914912018 @default.
- W2021791491 countsByYear W20217914912019 @default.
- W2021791491 countsByYear W20217914912021 @default.
- W2021791491 crossrefType "journal-article" @default.
- W2021791491 hasAuthorship W2021791491A5007348590 @default.
- W2021791491 hasAuthorship W2021791491A5021871878 @default.
- W2021791491 hasAuthorship W2021791491A5023646928 @default.
- W2021791491 hasAuthorship W2021791491A5025878951 @default.
- W2021791491 hasAuthorship W2021791491A5066306425 @default.
- W2021791491 hasConcept C126322002 @default.
- W2021791491 hasConcept C142724271 @default.
- W2021791491 hasConcept C150903083 @default.
- W2021791491 hasConcept C203014093 @default.
- W2021791491 hasConcept C207001950 @default.
- W2021791491 hasConcept C2775838275 @default.
- W2021791491 hasConcept C2776151105 @default.
- W2021791491 hasConcept C2776232574 @default.
- W2021791491 hasConcept C2776694085 @default.
- W2021791491 hasConcept C2777557582 @default.
- W2021791491 hasConcept C2777714996 @default.
- W2021791491 hasConcept C2778690821 @default.
- W2021791491 hasConcept C2779797417 @default.
- W2021791491 hasConcept C2780559512 @default.
- W2021791491 hasConcept C2781244666 @default.
- W2021791491 hasConcept C71924100 @default.
- W2021791491 hasConcept C86803240 @default.
- W2021791491 hasConceptScore W2021791491C126322002 @default.
- W2021791491 hasConceptScore W2021791491C142724271 @default.
- W2021791491 hasConceptScore W2021791491C150903083 @default.
- W2021791491 hasConceptScore W2021791491C203014093 @default.
- W2021791491 hasConceptScore W2021791491C207001950 @default.