FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2021794106> ?p ?o ?g. }

• W2021794106 endingPage "260" @default.
• W2021794106 startingPage "253" @default.
• W2021794106 abstract "Purpose: This study determined whether the Crataegus (Hawthorn species) special extract WS® 1442 stimulates the endothelial formation of nitric oxide (NO), a vasoprotective factor, and characterized the underlying mechanism. Methods and Results: Vascular reactivity was assessed in porcine coronary artery rings, reactive oxygen species (ROS) formation in artery sections by microscopy, and phosphorylation of Akt and endothelial NO synthase (eNOS) in endothelial cells by Western blot analysis. WS® 1442 caused endothelium-dependent relaxations in coronary artery rings, which were reduced by Nω-nitro-L-arginine (a competitive inhibitor of NO synthase) and by charybdotoxin plus apamin (two inhibitors of endothelium-derived hyperpolarizing factor-mediated responses). Relaxations to WS® 1442 were inhibited by intracellular ROS scavengers and inhibitors of Src and PI3-kinase, but not by an estrogen receptor antagonist. WS® 1442 stimulated the endothelial formation of ROS in artery sections, and a redox-sensitive phosphorylation of Akt and eNOS in endothelial cells. Conclusions: WS® 1442 induced endothelium-dependent NO-mediated relaxations of coronary artery rings through the redox-sensitive Src/PI3-kinase/Akt-dependent phosphorylation of eNOS." @default.
• W2021794106 created "2016-06-24" @default.
• W2021794106 creator A5019665090 @default.
• W2021794106 creator A5031347079 @default.
• W2021794106 creator A5047938386 @default.
• W2021794106 creator A5057684590 @default.
• W2021794106 creator A5068617049 @default.
• W2021794106 creator A5085060247 @default.
• W2021794106 date "2009-03-01" @default.
• W2021794106 modified "2023-10-17" @default.
• W2021794106 title "Crataegus Special Extract WS 1442 Causes Endothelium-dependent Relaxation via a Redox-sensitive Src- and Akt-dependent Activation of Endothelial NO Synthase but Not via Activation of Estrogen Receptors" @default.
• W2021794106 cites W117561388 @default.
• W2021794106 cites W1975618852 @default.
• W2021794106 cites W1999165695 @default.
• W2021794106 cites W2013708043 @default.
• W2021794106 cites W2018264979 @default.
• W2021794106 cites W2021429711 @default.
• W2021794106 cites W2023338930 @default.
• W2021794106 cites W2028121321 @default.
• W2021794106 cites W2037711564 @default.
• W2021794106 cites W2040692157 @default.
• W2021794106 cites W2043138902 @default.
• W2021794106 cites W2047492665 @default.
• W2021794106 cites W2055231611 @default.
• W2021794106 cites W2056617927 @default.
• W2021794106 cites W2058177873 @default.
• W2021794106 cites W2064702438 @default.
• W2021794106 cites W2074146656 @default.
• W2021794106 cites W2075577394 @default.
• W2021794106 cites W2080776250 @default.
• W2021794106 cites W2088355928 @default.
• W2021794106 cites W2112662230 @default.
• W2021794106 cites W2118780544 @default.
• W2021794106 cites W2124602130 @default.
• W2021794106 cites W2134402538 @default.
• W2021794106 cites W2138463362 @default.
• W2021794106 cites W2141422587 @default.
• W2021794106 cites W2143272819 @default.
• W2021794106 cites W2153473625 @default.
• W2021794106 cites W2153762158 @default.
• W2021794106 cites W2157479071 @default.
• W2021794106 cites W2161953383 @default.
• W2021794106 cites W2599555230 @default.
• W2021794106 doi "https://doi.org/10.1097/fjc.0b013e31819ccfc9" @default.
• W2021794106 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/19247189" @default.
• W2021794106 hasPublicationYear "2009" @default.
• W2021794106 type Work @default.
• W2021794106 sameAs 2021794106 @default.
• W2021794106 citedByCount "53" @default.
• W2021794106 countsByYear W20217941062012 @default.
• W2021794106 countsByYear W20217941062013 @default.
• W2021794106 countsByYear W20217941062014 @default.
• W2021794106 countsByYear W20217941062015 @default.
• W2021794106 countsByYear W20217941062016 @default.
• W2021794106 countsByYear W20217941062017 @default.
• W2021794106 countsByYear W20217941062018 @default.
• W2021794106 countsByYear W20217941062019 @default.
• W2021794106 countsByYear W20217941062020 @default.
• W2021794106 countsByYear W20217941062021 @default.
• W2021794106 countsByYear W20217941062022 @default.
• W2021794106 crossrefType "journal-article" @default.
• W2021794106 hasAuthorship W2021794106A5019665090 @default.
• W2021794106 hasAuthorship W2021794106A5031347079 @default.
• W2021794106 hasAuthorship W2021794106A5047938386 @default.
• W2021794106 hasAuthorship W2021794106A5057684590 @default.
• W2021794106 hasAuthorship W2021794106A5068617049 @default.
• W2021794106 hasAuthorship W2021794106A5085060247 @default.
• W2021794106 hasConcept C108636557 @default.
• W2021794106 hasConcept C11960822 @default.
• W2021794106 hasConcept C121608353 @default.
• W2021794106 hasConcept C126322002 @default.
• W2021794106 hasConcept C134018914 @default.
• W2021794106 hasConcept C181199279 @default.
• W2021794106 hasConcept C185592680 @default.
• W2021794106 hasConcept C2776992346 @default.
• W2021794106 hasConcept C2777622882 @default.
• W2021794106 hasConcept C2778326061 @default.
• W2021794106 hasConcept C530470458 @default.
• W2021794106 hasConcept C55493867 @default.
• W2021794106 hasConcept C71924100 @default.
• W2021794106 hasConcept C75217442 @default.
• W2021794106 hasConcept C84606932 @default.
• W2021794106 hasConcept C86803240 @default.
• W2021794106 hasConcept C95444343 @default.
• W2021794106 hasConceptScore W2021794106C108636557 @default.
• W2021794106 hasConceptScore W2021794106C11960822 @default.
• W2021794106 hasConceptScore W2021794106C121608353 @default.
• W2021794106 hasConceptScore W2021794106C126322002 @default.
• W2021794106 hasConceptScore W2021794106C134018914 @default.
• W2021794106 hasConceptScore W2021794106C181199279 @default.
• W2021794106 hasConceptScore W2021794106C185592680 @default.
• W2021794106 hasConceptScore W2021794106C2776992346 @default.
• W2021794106 hasConceptScore W2021794106C2777622882 @default.
• W2021794106 hasConceptScore W2021794106C2778326061 @default.
• W2021794106 hasConceptScore W2021794106C530470458 @default.
• W2021794106 hasConceptScore W2021794106C55493867 @default.
• W2021794106 hasConceptScore W2021794106C71924100 @default.
• W2021794106 hasConceptScore W2021794106C75217442 @default.

• next