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- W2021796324 abstract "Reductive amination of aldehydes and ketones using sodium cyanoborohydride and Rink's 4-(2′,4′-dimethoxyphenyl-aminomethyl)-phenoxymethyl-linked polystyrene resin [Rink's amine linker on copoly-(styrene-1%-divinylbenzene)]1 2 affords high yields of linker-bound, N-alkyl amines with excellent chemical selectivity. Subsequent coupling with acid derivatives gave derivatized N-substituted amides in excellent yields after cleavage from the solid-support." @default.
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- W2021796324 date "1997-12-01" @default.
- W2021796324 modified "2023-10-09" @default.
- W2021796324 title "Alkylation of Rink's amide linker on polystyrene resin: A reductive amination approach to modified amine-linkers for the solid phase synthesis of N-substituted amide derivatives" @default.
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- W2021796324 doi "https://doi.org/10.1016/s0040-4039(97)10279-9" @default.
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