FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2021812317> ?p ?o ?g. }

• W2021812317 endingPage "6" @default.
• W2021812317 startingPage "1" @default.
• W2021812317 abstract "Several studies report immunomodulatory effects of endogenous IL-10 after trauma. The present study investigates the effect of inhalative IL-10 administration on systemic and pulmonary inflammation in hemorrhagic shock. Male C57/BL6 mice (8 animals per group) were subjected to pressure-controlled hemorrhagic shock for 1.5 hrs followed by resuscitation and inhalative administration of either 50 μ L PBS (Shock group) or 50 μ g/kg recombinant mouse IL-10 dissolved in 50 μ L PBS (Shock + IL-10 group). Animals were sacrificed after 4.5 hrs of recovery and serum IL-6, IL-10, KC, and MCP-1 concentrations were measured with ELISA kits. Acute pulmonary inflammation was assessed by pulmonary myeloperoxidase (MPO) activity and pulmonary H&E histopathology. Inhalative IL-10 administration decreased pulmonary inflammation without altering the systemic concentrations of IL-6, IL-10, and KC. Serum MCP-1 levels were significantly reduced following inhalative IL-10 administration. These findings suggest that inhalative IL-10 administration may modulate the pulmonary microenvironment without major alterations of the systemic inflammatory response, thus minimizing the potential susceptibility to infection and sepsis." @default.
• W2021812317 created "2016-06-24" @default.
• W2021812317 creator A5016287183 @default.
• W2021812317 creator A5019624885 @default.
• W2021812317 creator A5053230976 @default.
• W2021812317 creator A5060284965 @default.
• W2021812317 creator A5078473802 @default.
• W2021812317 creator A5079148261 @default.
• W2021812317 creator A5088504701 @default.
• W2021812317 date "2012-01-01" @default.
• W2021812317 modified "2023-10-16" @default.
• W2021812317 title "Inhalative IL-10 Attenuates Pulmonary Inflammation following Hemorrhagic Shock without Major Alterations of the Systemic Inflammatory Response" @default.
• W2021812317 cites W1973371553 @default.
• W2021812317 cites W1980220254 @default.
• W2021812317 cites W1987073290 @default.
• W2021812317 cites W2005044353 @default.
• W2021812317 cites W2009539755 @default.
• W2021812317 cites W2017184884 @default.
• W2021812317 cites W2019050518 @default.
• W2021812317 cites W2025091287 @default.
• W2021812317 cites W2030015146 @default.
• W2021812317 cites W2030591858 @default.
• W2021812317 cites W2032054315 @default.
• W2021812317 cites W2034042813 @default.
• W2021812317 cites W2043661379 @default.
• W2021812317 cites W2045008505 @default.
• W2021812317 cites W2052037332 @default.
• W2021812317 cites W2058270614 @default.
• W2021812317 cites W2066597122 @default.
• W2021812317 cites W2069485575 @default.
• W2021812317 cites W2069960650 @default.
• W2021812317 cites W2083776964 @default.
• W2021812317 cites W2103270484 @default.
• W2021812317 cites W2123399131 @default.
• W2021812317 cites W2139754661 @default.
• W2021812317 cites W2143567520 @default.
• W2021812317 cites W2148080069 @default.
• W2021812317 cites W2150195134 @default.
• W2021812317 cites W2153976500 @default.
• W2021812317 cites W2161074777 @default.
• W2021812317 cites W2166312049 @default.
• W2021812317 cites W2406515573 @default.
• W2021812317 cites W99491017 @default.
• W2021812317 doi "https://doi.org/10.1155/2012/512974" @default.
• W2021812317 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3199193" @default.
• W2021812317 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/22046081" @default.
• W2021812317 hasPublicationYear "2012" @default.
• W2021812317 type Work @default.
• W2021812317 sameAs 2021812317 @default.
• W2021812317 citedByCount "19" @default.
• W2021812317 countsByYear W20218123172012 @default.
• W2021812317 countsByYear W20218123172013 @default.
• W2021812317 countsByYear W20218123172014 @default.
• W2021812317 countsByYear W20218123172015 @default.
• W2021812317 countsByYear W20218123172016 @default.
• W2021812317 countsByYear W20218123172018 @default.
• W2021812317 countsByYear W20218123172019 @default.
• W2021812317 countsByYear W20218123172020 @default.
• W2021812317 countsByYear W20218123172021 @default.
• W2021812317 countsByYear W20218123172022 @default.
• W2021812317 crossrefType "journal-article" @default.
• W2021812317 hasAuthorship W2021812317A5016287183 @default.
• W2021812317 hasAuthorship W2021812317A5019624885 @default.
• W2021812317 hasAuthorship W2021812317A5053230976 @default.
• W2021812317 hasAuthorship W2021812317A5060284965 @default.
• W2021812317 hasAuthorship W2021812317A5078473802 @default.
• W2021812317 hasAuthorship W2021812317A5079148261 @default.
• W2021812317 hasAuthorship W2021812317A5088504701 @default.
• W2021812317 hasBestOaLocation W20218123171 @default.
• W2021812317 hasConcept C126322002 @default.
• W2021812317 hasConcept C142724271 @default.
• W2021812317 hasConcept C150903083 @default.
• W2021812317 hasConcept C203014093 @default.
• W2021812317 hasConcept C203565725 @default.
• W2021812317 hasConcept C207001950 @default.
• W2021812317 hasConcept C25938499 @default.
• W2021812317 hasConcept C2776252253 @default.
• W2021812317 hasConcept C2776914184 @default.
• W2021812317 hasConcept C2778384902 @default.
• W2021812317 hasConcept C2780942790 @default.
• W2021812317 hasConcept C2781300812 @default.
• W2021812317 hasConcept C544855455 @default.
• W2021812317 hasConcept C71924100 @default.
• W2021812317 hasConcept C75603125 @default.
• W2021812317 hasConcept C86803240 @default.
• W2021812317 hasConcept C98274493 @default.
• W2021812317 hasConceptScore W2021812317C126322002 @default.
• W2021812317 hasConceptScore W2021812317C142724271 @default.
• W2021812317 hasConceptScore W2021812317C150903083 @default.
• W2021812317 hasConceptScore W2021812317C203014093 @default.
• W2021812317 hasConceptScore W2021812317C203565725 @default.
• W2021812317 hasConceptScore W2021812317C207001950 @default.
• W2021812317 hasConceptScore W2021812317C25938499 @default.
• W2021812317 hasConceptScore W2021812317C2776252253 @default.
• W2021812317 hasConceptScore W2021812317C2776914184 @default.
• W2021812317 hasConceptScore W2021812317C2778384902 @default.
• W2021812317 hasConceptScore W2021812317C2780942790 @default.
• W2021812317 hasConceptScore W2021812317C2781300812 @default.

• next