Matches in SemOpenAlex for { <https://semopenalex.org/work/W2021814928> ?p ?o ?g. }
Showing items 1 to 59 of
59
with 100 items per page.
- W2021814928 endingPage "1518" @default.
- W2021814928 startingPage "1517" @default.
- W2021814928 abstract "<h3>BACKGROUND:</h3> Mechanical insufflation/exsufflation (in-exsufflation) increases peak cough flow and may improve sputum clearance. No studies have compared current respiratory physiotherapy practice (manual percussion, shaking, and assisted cough) plus mechanical in-exsufflation to current physiotherapy practice without in-exsufflation in noninvasive-ventilation (NIV) dependent neuromuscular patients with an acute respiratory-tract infection. We hypothesized that airway clearance in these patients would be more effective with in-exsufflation, compared to without in-exsufflation. <h3>METHODS:</h3> Eight patients (6 male), median age 21.5 y (range 4-44 y). All had sputum retention, with an elevated C-reactive protein of 113 mg/L (range 13-231 mg/L) and a white-cell count of 14}10<sup>9</sup> cells/L (range 7-25}10<sup>9</sup> cells/L). Patients underwent a 2-day randomized crossover treatment program, with in-exsufflation for one session and without in-exsufflation for the second, with a reverse-crossover on the next day. Treatment time after 30 min (or earlier if sputum clearance was complete) was recorded. Outcome measures were heart rate, pulse oximetry (S<sub>pO<sub>2</sub></sub>), transcutaneous carbon dioxide tension (P<sub>tcCO<sub>2</sub></sub>), and independently assessed auscultation score. Patients rated effectiveness on a visual analog scale. <h3>RESULTS:</h3> Treatment time after 30 min was significantly shorter with in-exsufflation, versus without in-exsufflation session (30 + 0 = 30 min (range 0-26 min) vs 30 + 17 = 47 min (range 0-35 min) (<i>P</i> = .03). There was a significant improvement in auscultation score in both groups (with in-exsufflation 2.9 ± 1.9 to 1.8 ± 2.0, <i>P</i> = .02; without in-exsufflation 3.4 ± 2.0 to 2.3 ± 2.2, <i>P</i> = .007). Visual-analog-scale score for the amount of sputum cleared in both treatment groups showed a decline (<i>P</i> < .05). There was no difference in mean heart rate, S<sub>pO<sub>2</sub></sub>, or P<sub>tcCO<sub>2</sub></sub> with either treatment. <h3>CONCLUSIONS:</h3> This is a short-term study of the use of in-exsufflation as a supplement to standard NIV plus physiotherapy in a small group of patients with neuromuscular disease. The addition of mechanical in-exsufflation shortened airway-clearance sessions. The device appeared to be safe and well tolerated, and may provide additional benefit to patients with neuromuscular disease and upper-respiratory-tract infection; further studies are indicated." @default.
- W2021814928 created "2016-06-24" @default.
- W2021814928 creator A5056649904 @default.
- W2021814928 creator A5060487287 @default.
- W2021814928 date "1998-05-01" @default.
- W2021814928 modified "2023-10-17" @default.
- W2021814928 title "Do neurologists have a future in neuroimaging?" @default.
- W2021814928 cites W2074938381 @default.
- W2021814928 doi "https://doi.org/10.1212/wnl.50.5.1517" @default.
- W2021814928 hasPublicationYear "1998" @default.
- W2021814928 type Work @default.
- W2021814928 sameAs 2021814928 @default.
- W2021814928 citedByCount "0" @default.
- W2021814928 crossrefType "journal-article" @default.
- W2021814928 hasAuthorship W2021814928A5056649904 @default.
- W2021814928 hasAuthorship W2021814928A5060487287 @default.
- W2021814928 hasConcept C105922876 @default.
- W2021814928 hasConcept C142724271 @default.
- W2021814928 hasConcept C204787440 @default.
- W2021814928 hasConcept C27081682 @default.
- W2021814928 hasConcept C2776301714 @default.
- W2021814928 hasConcept C2776892627 @default.
- W2021814928 hasConcept C2780040553 @default.
- W2021814928 hasConcept C2781069245 @default.
- W2021814928 hasConcept C42219234 @default.
- W2021814928 hasConcept C71924100 @default.
- W2021814928 hasConcept C87813604 @default.
- W2021814928 hasConceptScore W2021814928C105922876 @default.
- W2021814928 hasConceptScore W2021814928C142724271 @default.
- W2021814928 hasConceptScore W2021814928C204787440 @default.
- W2021814928 hasConceptScore W2021814928C27081682 @default.
- W2021814928 hasConceptScore W2021814928C2776301714 @default.
- W2021814928 hasConceptScore W2021814928C2776892627 @default.
- W2021814928 hasConceptScore W2021814928C2780040553 @default.
- W2021814928 hasConceptScore W2021814928C2781069245 @default.
- W2021814928 hasConceptScore W2021814928C42219234 @default.
- W2021814928 hasConceptScore W2021814928C71924100 @default.
- W2021814928 hasConceptScore W2021814928C87813604 @default.
- W2021814928 hasIssue "5" @default.
- W2021814928 hasLocation W20218149281 @default.
- W2021814928 hasOpenAccess W2021814928 @default.
- W2021814928 hasPrimaryLocation W20218149281 @default.
- W2021814928 hasRelatedWork W1988465471 @default.
- W2021814928 hasRelatedWork W2329964806 @default.
- W2021814928 hasRelatedWork W2388904409 @default.
- W2021814928 hasRelatedWork W2389856622 @default.
- W2021814928 hasRelatedWork W2392989329 @default.
- W2021814928 hasRelatedWork W2549135832 @default.
- W2021814928 hasRelatedWork W2793472244 @default.
- W2021814928 hasRelatedWork W2992709694 @default.
- W2021814928 hasRelatedWork W3030157432 @default.
- W2021814928 hasRelatedWork W4238599390 @default.
- W2021814928 hasVolume "50" @default.
- W2021814928 isParatext "false" @default.
- W2021814928 isRetracted "false" @default.
- W2021814928 magId "2021814928" @default.
- W2021814928 workType "article" @default.