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- W2021832653 abstract "Two nitrogen-containing metabolites of myristicin (1-methoxy-2,3-methylenedioxy-5-allyl benzene) are excreted in the urine of rats and guinea pigs following oral or intraperitoneal administration. The major basic ninhydrin-positive urinary metabolite of myristicin in the rat is 3-piperidyl-1-(3′methoxy-4′,5′-methylenedioxyphenyl)-1-propanone, while the major basic ninhydrin-positive urinary metabolite of the guinea pig is 3-pyrrolidinyl-1-(3′methoxy-4′,5′-methylenedioxyphenyl)-1-propanone. In addition, the rat and guinea pig excrete trace quantities of the pyrrolidinyl ketone and piperidyl ketone, respectively. In contrast to the urinary basic metabolites of safrole, no detectable quantity of the N,N dimethylamino ketone was present in either rat or guinea pig urine after administration of myristicin; the guinea pig upon administration of safrole excreted only the substituted 3-NN-dimethyl amino propiophenone." @default.
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- W2021832653 date "1971-08-01" @default.
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- W2021832653 title "Urinary excretion of tertiary amino methoxy methylenedioxy propiophenones as metabolites of myristicin in the rat and guinea pig" @default.
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- W2021832653 doi "https://doi.org/10.1016/0304-4165(71)90233-9" @default.
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