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- W2021861028 abstract "T HE only anatomical variants that have been generally recognized in infants born of diabetic mothers are excessive body weight and increase in the size and number of the islands of Langerhans. Their exact incidence is not known, but it is significantly greater than in the normal newborn infant population. In the present communication it will be shown that other important deviations from the normal anatomy of the newborn infant are to be found in some infants born to diabetic mothers; namely, a marked hypertrophy of the heart and an increase in the erythropoietic tissue of tile liver. In fact, we have observed that macrosomia, hyperp]asia of the islands of Langerhans, cardiac hypertrophy, and erythroblastosis occur together in tile same infant in a surprising number of cases. Our attention was directed to these findings by a recent study made in this clinic of six infants born to diabetic mothers2 Two of the infants had by roentgen examination considerable enlargement of their hearts in the first few days of life. Similar observations have been made here in four additional infants. The observations in these ten infants led us to search the literature and the autopsy files of the New Haven Hospital, the New York tIospital,* and the Boston Lying-In Hospital} for anatomical confirmation of the roentgen evidence of" @default.
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- W2021861028 date "1943-09-01" @default.
- W2021861028 modified "2023-10-16" @default.
- W2021861028 title "Macrosomia, cardiac hypertrophy, erythroblastosis, and hyperplasia of the islands of langerhans in infants born to diabetic mothers" @default.
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- W2021861028 doi "https://doi.org/10.1016/s0022-3476(43)80001-9" @default.
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