Matches in SemOpenAlex for { <https://semopenalex.org/work/W2021868178> ?p ?o ?g. }
Showing items 1 to 91 of
91
with 100 items per page.
- W2021868178 endingPage "267" @default.
- W2021868178 startingPage "261" @default.
- W2021868178 abstract "Summary The generalized progressive retinal atrophies (gPRAs) form a group of retinal degenerations of pedigree dogs and cats, which have a variety of genetic origins (mostly unknown). We have examined the opsin gene for polymorphisms in several breeds of pedigree dog suffering from distinct forms of gPRA, by methods including single‐strand conformation polymorphism analysis, microsatellite analysis and direct sequencing. The breeds examined included the Tibetan terrier, the miniature schnauzer, the Irish setter, the miniature poodle, the Labrador retriever and the English cocker spaniel, as well as individuals from breeds in which PRA has not been described and of mixed breed. Individuals from each of the named breeds suffering from PRA were compared with clinically normal dogs. Two polymorphisms were found. One, segregating within the Tibetan terrier population, but not seen in other breeds, was a synonymous transition at nucleotide position 780 in exon 3. Inheritance of this polymorphism suggests that opsin is unlikely to contain mutations causative of gPRA in this breed. The other polymorphism occurred between all miniature schnauzers examined and dogs of other breeds. It consisted of a single base insertion in intron 2. No polymorphisms in the opsin sequence were detected in any other breed. DNA sequencing allowed rigorous exclusion of mutations in opsin as a cause of gPRA in miniature poodles, English cocker spaniels or Labrador retrievers." @default.
- W2021868178 created "2016-06-24" @default.
- W2021868178 creator A5001256641 @default.
- W2021868178 creator A5011524795 @default.
- W2021868178 creator A5022168061 @default.
- W2021868178 creator A5026066463 @default.
- W2021868178 creator A5030986471 @default.
- W2021868178 date "1995-08-01" @default.
- W2021868178 modified "2023-10-18" @default.
- W2021868178 title "Investigation of the role of opsin gene polymorphism in generalized progressive retinal atrophies in dogs" @default.
- W2021868178 cites W1791674900 @default.
- W2021868178 cites W1986202652 @default.
- W2021868178 cites W1996733925 @default.
- W2021868178 cites W2010598119 @default.
- W2021868178 cites W2012582259 @default.
- W2021868178 cites W2013803304 @default.
- W2021868178 cites W2037268137 @default.
- W2021868178 cites W2044562743 @default.
- W2021868178 cites W2051684999 @default.
- W2021868178 cites W2064304960 @default.
- W2021868178 cites W2069187736 @default.
- W2021868178 cites W2077274995 @default.
- W2021868178 cites W2083625623 @default.
- W2021868178 cites W2086859078 @default.
- W2021868178 cites W2121546784 @default.
- W2021868178 cites W2160101101 @default.
- W2021868178 cites W2162650178 @default.
- W2021868178 cites W2341723247 @default.
- W2021868178 cites W2493590780 @default.
- W2021868178 doi "https://doi.org/10.1111/j.1365-2052.1995.tb03253.x" @default.
- W2021868178 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/7661398" @default.
- W2021868178 hasPublicationYear "1995" @default.
- W2021868178 type Work @default.
- W2021868178 sameAs 2021868178 @default.
- W2021868178 citedByCount "19" @default.
- W2021868178 crossrefType "journal-article" @default.
- W2021868178 hasAuthorship W2021868178A5001256641 @default.
- W2021868178 hasAuthorship W2021868178A5011524795 @default.
- W2021868178 hasAuthorship W2021868178A5022168061 @default.
- W2021868178 hasAuthorship W2021868178A5026066463 @default.
- W2021868178 hasAuthorship W2021868178A5030986471 @default.
- W2021868178 hasConcept C104317684 @default.
- W2021868178 hasConcept C135763542 @default.
- W2021868178 hasConcept C149737253 @default.
- W2021868178 hasConcept C153209595 @default.
- W2021868178 hasConcept C180754005 @default.
- W2021868178 hasConcept C202033177 @default.
- W2021868178 hasConcept C2776482104 @default.
- W2021868178 hasConcept C2780827179 @default.
- W2021868178 hasConcept C30028475 @default.
- W2021868178 hasConcept C36823959 @default.
- W2021868178 hasConcept C54355233 @default.
- W2021868178 hasConcept C55493867 @default.
- W2021868178 hasConcept C61320498 @default.
- W2021868178 hasConcept C86803240 @default.
- W2021868178 hasConceptScore W2021868178C104317684 @default.
- W2021868178 hasConceptScore W2021868178C135763542 @default.
- W2021868178 hasConceptScore W2021868178C149737253 @default.
- W2021868178 hasConceptScore W2021868178C153209595 @default.
- W2021868178 hasConceptScore W2021868178C180754005 @default.
- W2021868178 hasConceptScore W2021868178C202033177 @default.
- W2021868178 hasConceptScore W2021868178C2776482104 @default.
- W2021868178 hasConceptScore W2021868178C2780827179 @default.
- W2021868178 hasConceptScore W2021868178C30028475 @default.
- W2021868178 hasConceptScore W2021868178C36823959 @default.
- W2021868178 hasConceptScore W2021868178C54355233 @default.
- W2021868178 hasConceptScore W2021868178C55493867 @default.
- W2021868178 hasConceptScore W2021868178C61320498 @default.
- W2021868178 hasConceptScore W2021868178C86803240 @default.
- W2021868178 hasIssue "4" @default.
- W2021868178 hasLocation W20218681781 @default.
- W2021868178 hasLocation W20218681782 @default.
- W2021868178 hasOpenAccess W2021868178 @default.
- W2021868178 hasPrimaryLocation W20218681781 @default.
- W2021868178 hasRelatedWork W1983016295 @default.
- W2021868178 hasRelatedWork W1989876250 @default.
- W2021868178 hasRelatedWork W2012315421 @default.
- W2021868178 hasRelatedWork W2056120977 @default.
- W2021868178 hasRelatedWork W2071250685 @default.
- W2021868178 hasRelatedWork W2093269861 @default.
- W2021868178 hasRelatedWork W2154811188 @default.
- W2021868178 hasRelatedWork W2407894832 @default.
- W2021868178 hasRelatedWork W3120355442 @default.
- W2021868178 hasRelatedWork W2547553420 @default.
- W2021868178 hasVolume "26" @default.
- W2021868178 isParatext "false" @default.
- W2021868178 isRetracted "false" @default.
- W2021868178 magId "2021868178" @default.
- W2021868178 workType "article" @default.