FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2021880300> ?p ?o ?g. }

• W2021880300 endingPage "1484" @default.
• W2021880300 startingPage "1476" @default.
• W2021880300 abstract "Grass carp (Ctenopharyngodon idellus) is a very important aquaculture species in China and other South-East Asian countries; however, disease outbreaks in this species are frequent, resulting in huge economic losses. Grass carp hemorrhage caused by grass carp reovirus (GCRV) is one of the most serious diseases. Junction adhesion molecule A (JAM-A) is the mammalian receptor for reovirus, and has been well studied. However, the JAM-A gene in grass carp has not been studied so far. In this study, we cloned and elucidated the structure of the JAM-A gene in grass carp (GcJAM-A) and then studied its functions during grass carp hemorrhage. GcJAM-A is composed of 10 exons and 9 introns, and its full-length cDNA is 1833 bp long, with an 888 bp open reading frame (ORF) that encodes a 295 amino acid protein. The GcJAM-A protein is predicted to contain a typical transmembrane domain. Maternal expression pattern of GcJAM-A is observed during early embryogenesis, while zygote expression occurs at 8 h after hatching. GcJAM-A is expressed strongly in the gill, liver, intestine and kidney, while it is expressed poorly in the blood, brain, spleen and head kidney. Moreover, lower expression is observed in the gill, liver, intestine, brain, spleen and kidney of 30-month-old individuals, compared with 6-month-old. In a GcJAM-A-knockdown cell line (CIK) infected with GCRV, the expression of genes involved in the interferon and apoptosis pathways was significantly inhibited. These results suggest that GcJAM-A could be a receptor for GCRV. We have therefore managed to characterize the GcJAM-A gene and provide evidence for its role as a receptor for GCRV." @default.
• W2021880300 created "2016-06-24" @default.
• W2021880300 creator A5040290579 @default.
• W2021880300 creator A5050005422 @default.
• W2021880300 creator A5056276396 @default.
• W2021880300 creator A5070902065 @default.
• W2021880300 creator A5074760691 @default.
• W2021880300 creator A5086161254 @default.
• W2021880300 date "2013-06-01" @default.
• W2021880300 modified "2023-10-17" @default.
• W2021880300 title "Cloning and preliminary functional studies of the JAM-A gene in grass carp (Ctenopharyngodon idellus)" @default.
• W2021880300 cites W1481827372 @default.
• W2021880300 cites W1565555821 @default.
• W2021880300 cites W1608055671 @default.
• W2021880300 cites W1790932677 @default.
• W2021880300 cites W1963858026 @default.
• W2021880300 cites W1971637651 @default.
• W2021880300 cites W1976242723 @default.
• W2021880300 cites W1985115511 @default.
• W2021880300 cites W1988098087 @default.
• W2021880300 cites W2006441710 @default.
• W2021880300 cites W2008085205 @default.
• W2021880300 cites W2012049306 @default.
• W2021880300 cites W2012111901 @default.
• W2021880300 cites W2016996110 @default.
• W2021880300 cites W2022866908 @default.
• W2021880300 cites W2023779968 @default.
• W2021880300 cites W2028175599 @default.
• W2021880300 cites W2033630490 @default.
• W2021880300 cites W2037681980 @default.
• W2021880300 cites W2038470517 @default.
• W2021880300 cites W2076868305 @default.
• W2021880300 cites W2078575853 @default.
• W2021880300 cites W2086550332 @default.
• W2021880300 cites W2113047516 @default.
• W2021880300 cites W2122170158 @default.
• W2021880300 cites W2128324936 @default.
• W2021880300 cites W2131516248 @default.
• W2021880300 cites W2142698394 @default.
• W2021880300 cites W2158926036 @default.
• W2021880300 cites W2160063406 @default.
• W2021880300 cites W2171143508 @default.
• W2021880300 cites W2335213807 @default.
• W2021880300 cites W2345609573 @default.
• W2021880300 doi "https://doi.org/10.1016/j.fsi.2013.03.352" @default.
• W2021880300 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23542603" @default.
• W2021880300 hasPublicationYear "2013" @default.
• W2021880300 type Work @default.
• W2021880300 sameAs 2021880300 @default.
• W2021880300 citedByCount "18" @default.
• W2021880300 countsByYear W20218803002014 @default.
• W2021880300 countsByYear W20218803002015 @default.
• W2021880300 countsByYear W20218803002016 @default.
• W2021880300 countsByYear W20218803002017 @default.
• W2021880300 countsByYear W20218803002018 @default.
• W2021880300 countsByYear W20218803002019 @default.
• W2021880300 countsByYear W20218803002020 @default.
• W2021880300 countsByYear W20218803002021 @default.
• W2021880300 countsByYear W20218803002023 @default.
• W2021880300 crossrefType "journal-article" @default.
• W2021880300 hasAuthorship W2021880300A5040290579 @default.
• W2021880300 hasAuthorship W2021880300A5050005422 @default.
• W2021880300 hasAuthorship W2021880300A5056276396 @default.
• W2021880300 hasAuthorship W2021880300A5070902065 @default.
• W2021880300 hasAuthorship W2021880300A5074760691 @default.
• W2021880300 hasAuthorship W2021880300A5086161254 @default.
• W2021880300 hasConcept C104317684 @default.
• W2021880300 hasConcept C121050878 @default.
• W2021880300 hasConcept C153911025 @default.
• W2021880300 hasConcept C167625842 @default.
• W2021880300 hasConcept C173396325 @default.
• W2021880300 hasConcept C187882448 @default.
• W2021880300 hasConcept C199360897 @default.
• W2021880300 hasConcept C2781257293 @default.
• W2021880300 hasConcept C2909208804 @default.
• W2021880300 hasConcept C36823959 @default.
• W2021880300 hasConcept C41008148 @default.
• W2021880300 hasConcept C47289529 @default.
• W2021880300 hasConcept C505870484 @default.
• W2021880300 hasConcept C54355233 @default.
• W2021880300 hasConcept C86803240 @default.
• W2021880300 hasConceptScore W2021880300C104317684 @default.
• W2021880300 hasConceptScore W2021880300C121050878 @default.
• W2021880300 hasConceptScore W2021880300C153911025 @default.
• W2021880300 hasConceptScore W2021880300C167625842 @default.
• W2021880300 hasConceptScore W2021880300C173396325 @default.
• W2021880300 hasConceptScore W2021880300C187882448 @default.
• W2021880300 hasConceptScore W2021880300C199360897 @default.
• W2021880300 hasConceptScore W2021880300C2781257293 @default.
• W2021880300 hasConceptScore W2021880300C2909208804 @default.
• W2021880300 hasConceptScore W2021880300C36823959 @default.
• W2021880300 hasConceptScore W2021880300C41008148 @default.
• W2021880300 hasConceptScore W2021880300C47289529 @default.
• W2021880300 hasConceptScore W2021880300C505870484 @default.
• W2021880300 hasConceptScore W2021880300C54355233 @default.
• W2021880300 hasConceptScore W2021880300C86803240 @default.
• W2021880300 hasFunder F4320321001 @default.
• W2021880300 hasIssue "6" @default.

• next