FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2021890186> ?p ?o ?g. }

• W2021890186 endingPage "495" @default.
• W2021890186 startingPage "489" @default.
• W2021890186 abstract "The scope of this review is to discuss the new advances in our understanding of the role of scavenger receptor class A in the initiation and modulation of the atherosclerotic process. Through the approaches of gene manipulation in the mouse model, a substantial body of literature has accumulated that depicts scavenger receptor class A as a central player in atherogenesis. In studies of scavenger receptor class A overexpression in macrophages through bone marrow transplantation using transgenic donor material, recipient mice with hyperlipidemia caused either by apolipoprotein E or LDL receptor deficiency did not show convincing changes in the degree of atherosclerosis development compared with controls. Conversely, the deletion of the scavenger receptor class A gene in the mouse has shown, in a consistent and significant fashion, that this receptor serves a pro-atherogenic function under hyperlipidemic conditions, as both apolipoprotein E and LDL receptor-deficient mice had reduced atherosclerosis in the absence of scavenger receptor class A. In addition, we have recently shown that C57BL/6 mice are protected from diet-induced atherosclerosis when they lack scavenger receptor class A, and that the macrophage is the cell type responsible for the effect of scavenger receptor class A deficiency in reducing lesion formation in C57BL/6 and LDL receptor null mice. Together, these results demonstrate that macrophage scavenger receptor class A contributes significantly to atherosclerotic lesion formation, and suggest that the uptake of oxidized or modified lipoproteins by vessel wall macrophages is a central process in atherogenesis." @default.
• W2021890186 created "2016-06-24" @default.
• W2021890186 creator A5067797353 @default.
• W2021890186 creator A5089000198 @default.
• W2021890186 date "2001-10-01" @default.
• W2021890186 modified "2023-10-07" @default.
• W2021890186 title "Class A scavenger receptors, macrophages, and atherosclerosis" @default.
• W2021890186 cites W1574193072 @default.
• W2021890186 cites W1927081389 @default.
• W2021890186 cites W1948956778 @default.
• W2021890186 cites W1966388070 @default.
• W2021890186 cites W1976621212 @default.
• W2021890186 cites W1978383066 @default.
• W2021890186 cites W1981415483 @default.
• W2021890186 cites W1982174125 @default.
• W2021890186 cites W2001399393 @default.
• W2021890186 cites W2005659583 @default.
• W2021890186 cites W2010005650 @default.
• W2021890186 cites W2013777741 @default.
• W2021890186 cites W2022865224 @default.
• W2021890186 cites W2024217097 @default.
• W2021890186 cites W2032272012 @default.
• W2021890186 cites W2036906162 @default.
• W2021890186 cites W2037599912 @default.
• W2021890186 cites W2038484123 @default.
• W2021890186 cites W2049401036 @default.
• W2021890186 cites W2058060182 @default.
• W2021890186 cites W2058194924 @default.
• W2021890186 cites W2059562120 @default.
• W2021890186 cites W2063329261 @default.
• W2021890186 cites W2063813098 @default.
• W2021890186 cites W2064244952 @default.
• W2021890186 cites W2065372271 @default.
• W2021890186 cites W2070690965 @default.
• W2021890186 cites W2070983876 @default.
• W2021890186 cites W2096096506 @default.
• W2021890186 cites W2107611361 @default.
• W2021890186 cites W2107795872 @default.
• W2021890186 cites W2111912537 @default.
• W2021890186 cites W2112807003 @default.
• W2021890186 cites W2113424839 @default.
• W2021890186 cites W2118877270 @default.
• W2021890186 cites W2120809415 @default.
• W2021890186 cites W2125539464 @default.
• W2021890186 cites W2128516095 @default.
• W2021890186 cites W2134605118 @default.
• W2021890186 cites W2135364407 @default.
• W2021890186 cites W2136637225 @default.
• W2021890186 cites W2138079858 @default.
• W2021890186 cites W2142174657 @default.
• W2021890186 cites W2148460023 @default.
• W2021890186 cites W2153245546 @default.
• W2021890186 cites W2162458714 @default.
• W2021890186 cites W2163548953 @default.
• W2021890186 cites W2165235458 @default.
• W2021890186 cites W2171938486 @default.
• W2021890186 cites W2290570357 @default.
• W2021890186 cites W2343889361 @default.
• W2021890186 doi "https://doi.org/10.1097/00041433-200110000-00003" @default.
• W2021890186 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/11561167" @default.
• W2021890186 hasPublicationYear "2001" @default.
• W2021890186 type Work @default.
• W2021890186 sameAs 2021890186 @default.
• W2021890186 citedByCount "110" @default.
• W2021890186 countsByYear W20218901862012 @default.
• W2021890186 countsByYear W20218901862013 @default.
• W2021890186 countsByYear W20218901862014 @default.
• W2021890186 countsByYear W20218901862015 @default.
• W2021890186 countsByYear W20218901862016 @default.
• W2021890186 countsByYear W20218901862017 @default.
• W2021890186 countsByYear W20218901862018 @default.
• W2021890186 countsByYear W20218901862019 @default.
• W2021890186 countsByYear W20218901862020 @default.
• W2021890186 countsByYear W20218901862021 @default.
• W2021890186 countsByYear W20218901862022 @default.
• W2021890186 countsByYear W20218901862023 @default.
• W2021890186 crossrefType "journal-article" @default.
• W2021890186 hasAuthorship W2021890186A5067797353 @default.
• W2021890186 hasAuthorship W2021890186A5089000198 @default.
• W2021890186 hasConcept C126322002 @default.
• W2021890186 hasConcept C134018914 @default.
• W2021890186 hasConcept C170493617 @default.
• W2021890186 hasConcept C185592680 @default.
• W2021890186 hasConcept C202751555 @default.
• W2021890186 hasConcept C203014093 @default.
• W2021890186 hasConcept C2777895019 @default.
• W2021890186 hasConcept C2778163477 @default.
• W2021890186 hasConcept C2779091943 @default.
• W2021890186 hasConcept C2779244956 @default.
• W2021890186 hasConcept C2780072125 @default.
• W2021890186 hasConcept C41443022 @default.
• W2021890186 hasConcept C43554185 @default.
• W2021890186 hasConcept C55493867 @default.
• W2021890186 hasConcept C555293320 @default.
• W2021890186 hasConcept C71924100 @default.
• W2021890186 hasConcept C86803240 @default.
• W2021890186 hasConcept C95444343 @default.
• W2021890186 hasConceptScore W2021890186C126322002 @default.

• next