FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2021950158> ?p ?o ?g. }

• W2021950158 abstract "In this issue of Circulation: Cardiovascular Interventions , a pilot study by Gotberg et al1 deserves notice. It may have major implications for clinicians who deal with myocardial infarction, and it suggests important insights into the poorly understood area of human reperfusion injury.Article see p 400The investigator team is to be congratulated for successfully surmounting a formidable implementation challenge. Within 30 minutes, they were able to rapidly cool patient body temperatures to an average less than the target temperature of <35°C without allowing the induction of cooling to interfere with or prolong the door-to-balloon time for percutaneous coronary intervention. To put this 30-minute speed of cooling into perspective, a 2010 investigation of human hypothermia from Australia reported a nearly 8-hour time interval to achieve temperatures <34°C in patients with cardiac arrest.2 The Gotberg pilot study goes on to describe a 38% reduction in infarct size and 43% reduction in peak troponin T release for the patients who received cooling before coronary reperfusion versus controls who received standard reperfusion within the same time period. The study raises an important clinical question that we must address: Is cool reperfusion the best reperfusion?An even more crucial scientific question lies just beneath the surface of these data: Does reperfusion injury exist in humans, and if so, does it have any relevance in terms of long-term function or tissue injury? Reperfusion injury remains controversial since its first description in the 1970s when it was observed that reoxygenation of the ischemic perfused isolated heart resulted in a large release of cardiac injury enzymes along with structural cellular damage seen extensively during reperfusion but only very minimally during the preceding ischemia.3,4 The notion of reperfusion injury suggested that some portion of cell death was caused by the conditions of …" @default.
• W2021950158 created "2016-06-24" @default.
• W2021950158 creator A5083278720 @default.
• W2021950158 date "2010-10-01" @default.
• W2021950158 modified "2023-09-24" @default.
• W2021950158 title "Does Cool Reperfusion Limit Myocardial Infarction Injury?" @default.
• W2021950158 cites W1728066272 @default.
• W2021950158 cites W2003788012 @default.
• W2021950158 cites W2015228484 @default.
• W2021950158 cites W2024560631 @default.
• W2021950158 cites W2037121432 @default.
• W2021950158 cites W2046419819 @default.
• W2021950158 cites W2048547503 @default.
• W2021950158 cites W2051909997 @default.
• W2021950158 cites W2071730783 @default.
• W2021950158 cites W2081787098 @default.
• W2021950158 cites W2091759075 @default.
• W2021950158 cites W2096548270 @default.
• W2021950158 cites W2104869294 @default.
• W2021950158 cites W2110565948 @default.
• W2021950158 cites W2122974654 @default.
• W2021950158 cites W2137429382 @default.
• W2021950158 cites W2145427448 @default.
• W2021950158 cites W2153298328 @default.
• W2021950158 cites W2160252183 @default.
• W2021950158 cites W2160419398 @default.
• W2021950158 cites W2170534435 @default.
• W2021950158 cites W2214094658 @default.
• W2021950158 cites W2768019923 @default.
• W2021950158 doi "https://doi.org/10.1161/circinterventions.110.958546" @default.
• W2021950158 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/20959597" @default.
• W2021950158 hasPublicationYear "2010" @default.
• W2021950158 type Work @default.
• W2021950158 sameAs 2021950158 @default.
• W2021950158 citedByCount "2" @default.
• W2021950158 countsByYear W20219501582013 @default.
• W2021950158 crossrefType "journal-article" @default.
• W2021950158 hasAuthorship W2021950158A5083278720 @default.
• W2021950158 hasBestOaLocation W20219501581 @default.
• W2021950158 hasConcept C126322002 @default.
• W2021950158 hasConcept C164705383 @default.
• W2021950158 hasConcept C2777390192 @default.
• W2021950158 hasConcept C2780114680 @default.
• W2021950158 hasConcept C2780400711 @default.
• W2021950158 hasConcept C2911020856 @default.
• W2021950158 hasConcept C500558357 @default.
• W2021950158 hasConcept C541997718 @default.
• W2021950158 hasConcept C71924100 @default.
• W2021950158 hasConceptScore W2021950158C126322002 @default.
• W2021950158 hasConceptScore W2021950158C164705383 @default.
• W2021950158 hasConceptScore W2021950158C2777390192 @default.
• W2021950158 hasConceptScore W2021950158C2780114680 @default.
• W2021950158 hasConceptScore W2021950158C2780400711 @default.
• W2021950158 hasConceptScore W2021950158C2911020856 @default.
• W2021950158 hasConceptScore W2021950158C500558357 @default.
• W2021950158 hasConceptScore W2021950158C541997718 @default.
• W2021950158 hasConceptScore W2021950158C71924100 @default.
• W2021950158 hasLocation W20219501581 @default.
• W2021950158 hasLocation W20219501582 @default.
• W2021950158 hasOpenAccess W2021950158 @default.
• W2021950158 hasPrimaryLocation W20219501581 @default.
• W2021950158 hasRelatedWork W1508906946 @default.
• W2021950158 hasRelatedWork W1980314370 @default.
• W2021950158 hasRelatedWork W2037872607 @default.
• W2021950158 hasRelatedWork W2038641419 @default.
• W2021950158 hasRelatedWork W2055371214 @default.
• W2021950158 hasRelatedWork W2056944171 @default.
• W2021950158 hasRelatedWork W2063459967 @default.
• W2021950158 hasRelatedWork W2080045599 @default.
• W2021950158 hasRelatedWork W2086164892 @default.
• W2021950158 hasRelatedWork W2184884965 @default.
• W2021950158 hasRelatedWork W2198680525 @default.
• W2021950158 hasRelatedWork W2216606362 @default.
• W2021950158 hasRelatedWork W2326660728 @default.
• W2021950158 hasRelatedWork W2355201485 @default.
• W2021950158 hasRelatedWork W3130281324 @default.
• W2021950158 hasRelatedWork W632805 @default.
• W2021950158 hasRelatedWork W75583138 @default.
• W2021950158 hasRelatedWork W2314557077 @default.
• W2021950158 hasRelatedWork W2417844315 @default.
• W2021950158 hasRelatedWork W2471732938 @default.
• W2021950158 isParatext "false" @default.
• W2021950158 isRetracted "false" @default.
• W2021950158 magId "2021950158" @default.
• W2021950158 workType "article" @default.