FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2021961431> ?p ?o ?g. }

• W2021961431 endingPage "1776" @default.
• W2021961431 startingPage "1765" @default.
• W2021961431 abstract "Different T cell subsets exhibit distinct capacities to migrate into peripheral sites of inflammation, and this may in part reflect differential expression of homing receptors and chemokine receptors. Using an adoptive transfer approach, we examined the ability of functionally distinct subsets of T cells to home to a peripheral inflammatory site. The data directly demonstrate the inability of naive T cells and the ability of effector cells to home to inflamed peritoneum. Furthermore, interleukin (IL)-12 directs the differentiation of either CD4(+) or CD8(+) T cells into effector populations that expresses functional E- and P-selectin ligand and that are preferentially recruited into the inflamed peritoneum compared with T cells differentiated in the presence of IL-4. Recruitment can be blocked by anti-E- and -P-selectin antibodies. The presence of antigen in the peritoneum promotes local proliferation of recruited T cells, and significantly amplifies the Th1 polarization of the lymphocytic infiltrate. Preferential recruitment of Th1 cells into the peritoneum is also seen when cytokine response gene 2 (CRG-2)/interferon gamma-inducible protein 10 (IP-10) is used as the sole inflammatory stimulus. We have also found that P-selectin binds only to antigen-specific T cells in draining lymph nodes after immunization, implying that both antigen- and cytokine-mediated signals are required for expression of functional selectin-ligand." @default.
• W2021961431 created "2016-06-24" @default.
• W2021961431 creator A5027842476 @default.
• W2021961431 creator A5029116436 @default.
• W2021961431 creator A5067645113 @default.
• W2021961431 creator A5072998974 @default.
• W2021961431 date "1999-06-07" @default.
• W2021961431 modified "2023-09-27" @default.
• W2021961431 title "Acquisition of Selectin Binding and Peripheral Homing Properties by CD4+ and CD8+ T Cells" @default.
• W2021961431 cites W139308946 @default.
• W2021961431 cites W1485881176 @default.
• W2021961431 cites W1489241767 @default.
• W2021961431 cites W1494363796 @default.
• W2021961431 cites W1503122218 @default.
• W2021961431 cites W1533977973 @default.
• W2021961431 cites W1538469124 @default.
• W2021961431 cites W1542489814 @default.
• W2021961431 cites W1572005725 @default.
• W2021961431 cites W1595980407 @default.
• W2021961431 cites W1598189172 @default.
• W2021961431 cites W1599274975 @default.
• W2021961431 cites W1607759608 @default.
• W2021961431 cites W1849720919 @default.
• W2021961431 cites W1965410838 @default.
• W2021961431 cites W1968284075 @default.
• W2021961431 cites W1970866345 @default.
• W2021961431 cites W1972922050 @default.
• W2021961431 cites W1976053716 @default.
• W2021961431 cites W1979514172 @default.
• W2021961431 cites W1979657237 @default.
• W2021961431 cites W1988379927 @default.
• W2021961431 cites W1995905351 @default.
• W2021961431 cites W1997196395 @default.
• W2021961431 cites W1998377021 @default.
• W2021961431 cites W2005659566 @default.
• W2021961431 cites W2007348558 @default.
• W2021961431 cites W2015201031 @default.
• W2021961431 cites W2017939175 @default.
• W2021961431 cites W2018590888 @default.
• W2021961431 cites W2031347383 @default.
• W2021961431 cites W2036160208 @default.
• W2021961431 cites W2042383304 @default.
• W2021961431 cites W2045008512 @default.
• W2021961431 cites W2045887180 @default.
• W2021961431 cites W2047916715 @default.
• W2021961431 cites W2058023151 @default.
• W2021961431 cites W2060338116 @default.
• W2021961431 cites W2062264071 @default.
• W2021961431 cites W2068552731 @default.
• W2021961431 cites W2080661022 @default.
• W2021961431 cites W2081596482 @default.
• W2021961431 cites W2087372329 @default.
• W2021961431 cites W2091301099 @default.
• W2021961431 cites W2099027783 @default.
• W2021961431 cites W2099675490 @default.
• W2021961431 cites W2102440756 @default.
• W2021961431 cites W2104050261 @default.
• W2021961431 cites W2104315875 @default.
• W2021961431 cites W2106473403 @default.
• W2021961431 cites W2106826370 @default.
• W2021961431 cites W2117342688 @default.
• W2021961431 cites W2125650988 @default.
• W2021961431 cites W2131799581 @default.
• W2021961431 cites W2135705262 @default.
• W2021961431 cites W2145245707 @default.
• W2021961431 cites W2148997371 @default.
• W2021961431 cites W2153869022 @default.
• W2021961431 cites W2158782513 @default.
• W2021961431 cites W2160129587 @default.
• W2021961431 cites W2162433609 @default.
• W2021961431 cites W2165208698 @default.
• W2021961431 cites W2168485942 @default.
• W2021961431 cites W4313343458 @default.
• W2021961431 doi "https://doi.org/10.1084/jem.189.11.1765" @default.
• W2021961431 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2193075" @default.
• W2021961431 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/10359580" @default.
• W2021961431 hasPublicationYear "1999" @default.
• W2021961431 type Work @default.
• W2021961431 sameAs 2021961431 @default.
• W2021961431 citedByCount "139" @default.
• W2021961431 countsByYear W20219614312013 @default.
• W2021961431 countsByYear W20219614312014 @default.
• W2021961431 countsByYear W20219614312015 @default.
• W2021961431 countsByYear W20219614312016 @default.
• W2021961431 countsByYear W20219614312017 @default.
• W2021961431 countsByYear W20219614312020 @default.
• W2021961431 countsByYear W20219614312022 @default.
• W2021961431 countsByYear W20219614312023 @default.
• W2021961431 crossrefType "journal-article" @default.
• W2021961431 hasAuthorship W2021961431A5027842476 @default.
• W2021961431 hasAuthorship W2021961431A5029116436 @default.
• W2021961431 hasAuthorship W2021961431A5067645113 @default.
• W2021961431 hasAuthorship W2021961431A5072998974 @default.
• W2021961431 hasBestOaLocation W20219614311 @default.
• W2021961431 hasConcept C129374314 @default.
• W2021961431 hasConcept C139563560 @default.
• W2021961431 hasConcept C147483822 @default.
• W2021961431 hasConcept C1491633281 @default.

• next