FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2021985872> ?p ?o ?g. }

• W2021985872 endingPage "498" @default.
• W2021985872 startingPage "491" @default.
• W2021985872 abstract "The anti-obesity and anti-diabetic effects of CL 316,243, a highly specific beta 3-adrenoceptor agonist (beta 1: beta 2: beta 3 = 0:1:100,000), were evaluated in obese diabetic yellow KK mice and C57Bl control mice. The study compound was fed through a gastric tube at a rate of 0.1 mg/kg/day for 2 weeks. The following parameters were compared in the treated and control animals given distilled water: brown adipose tissue thermogenesis, resting metabolic rate, insulin receptors in adipocytes, and blood glucose and serum insulin levels during a glucose overloading test. CL 316,243 significantly increased brown adipose tissue thermogenesis and resting metabolic rate in both yellow KK mice and C57Bl controls. The amount of white adipose tissue decreased, although food intake was not affected. The effects contributed to the mitigation of obesity in yellow KK mice. CL 316,243 also increased the concentration of insulin receptors and decreased the levels of serum insulin and blood glucose during the glucose overloading test in yellow KK mice. These observations suggest that CL 316,243 possesses anti-obesity and anti-diabetic effects and consequently may be useful for treating obesity as well as non-insulin-dependent diabetes mellitus in obese persons, without causing excessive side effects." @default.
• W2021985872 created "2016-06-24" @default.
• W2021985872 creator A5030594119 @default.
• W2021985872 creator A5060437712 @default.
• W2021985872 creator A5061971295 @default.
• W2021985872 creator A5067362453 @default.
• W2021985872 creator A5091512008 @default.
• W2021985872 date "1994-01-01" @default.
• W2021985872 modified "2023-10-04" @default.
• W2021985872 title "Anti-obesity and anti-diabetic effects of CL 316, 243, a highly specific β3-adrenoceptor agonist, in yellow KK mice" @default.
• W2021985872 cites W109691321 @default.
• W2021985872 cites W1775749144 @default.
• W2021985872 cites W1808051607 @default.
• W2021985872 cites W1979064868 @default.
• W2021985872 cites W1996476516 @default.
• W2021985872 cites W1998632508 @default.
• W2021985872 cites W2001426305 @default.
• W2021985872 cites W2002896923 @default.
• W2021985872 cites W2003975258 @default.
• W2021985872 cites W2015912619 @default.
• W2021985872 cites W2019100110 @default.
• W2021985872 cites W2026399791 @default.
• W2021985872 cites W2027180215 @default.
• W2021985872 cites W2044887777 @default.
• W2021985872 cites W2064587515 @default.
• W2021985872 cites W2074929337 @default.
• W2021985872 cites W2117821842 @default.
• W2021985872 cites W2143873575 @default.
• W2021985872 cites W2255676887 @default.
• W2021985872 cites W2403196200 @default.
• W2021985872 cites W2910062165 @default.
• W2021985872 cites W4252804584 @default.
• W2021985872 doi "https://doi.org/10.1016/0024-3205(94)00408-0" @default.
• W2021985872 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/8309351" @default.
• W2021985872 hasPublicationYear "1994" @default.
• W2021985872 type Work @default.
• W2021985872 sameAs 2021985872 @default.
• W2021985872 citedByCount "96" @default.
• W2021985872 countsByYear W20219858722012 @default.
• W2021985872 countsByYear W20219858722013 @default.
• W2021985872 countsByYear W20219858722014 @default.
• W2021985872 countsByYear W20219858722015 @default.
• W2021985872 countsByYear W20219858722016 @default.
• W2021985872 countsByYear W20219858722017 @default.
• W2021985872 countsByYear W20219858722018 @default.
• W2021985872 countsByYear W20219858722019 @default.
• W2021985872 countsByYear W20219858722020 @default.
• W2021985872 countsByYear W20219858722021 @default.
• W2021985872 countsByYear W20219858722022 @default.
• W2021985872 countsByYear W20219858722023 @default.
• W2021985872 crossrefType "journal-article" @default.
• W2021985872 hasAuthorship W2021985872A5030594119 @default.
• W2021985872 hasAuthorship W2021985872A5060437712 @default.
• W2021985872 hasAuthorship W2021985872A5061971295 @default.
• W2021985872 hasAuthorship W2021985872A5067362453 @default.
• W2021985872 hasAuthorship W2021985872A5091512008 @default.
• W2021985872 hasConcept C126322002 @default.
• W2021985872 hasConcept C134018914 @default.
• W2021985872 hasConcept C151279926 @default.
• W2021985872 hasConcept C151955695 @default.
• W2021985872 hasConcept C170493617 @default.
• W2021985872 hasConcept C171089720 @default.
• W2021985872 hasConcept C185592680 @default.
• W2021985872 hasConcept C2777391703 @default.
• W2021985872 hasConcept C2778938600 @default.
• W2021985872 hasConcept C2779306644 @default.
• W2021985872 hasConcept C2780642333 @default.
• W2021985872 hasConcept C511355011 @default.
• W2021985872 hasConcept C555293320 @default.
• W2021985872 hasConcept C71924100 @default.
• W2021985872 hasConceptScore W2021985872C126322002 @default.
• W2021985872 hasConceptScore W2021985872C134018914 @default.
• W2021985872 hasConceptScore W2021985872C151279926 @default.
• W2021985872 hasConceptScore W2021985872C151955695 @default.
• W2021985872 hasConceptScore W2021985872C170493617 @default.
• W2021985872 hasConceptScore W2021985872C171089720 @default.
• W2021985872 hasConceptScore W2021985872C185592680 @default.
• W2021985872 hasConceptScore W2021985872C2777391703 @default.
• W2021985872 hasConceptScore W2021985872C2778938600 @default.
• W2021985872 hasConceptScore W2021985872C2779306644 @default.
• W2021985872 hasConceptScore W2021985872C2780642333 @default.
• W2021985872 hasConceptScore W2021985872C511355011 @default.
• W2021985872 hasConceptScore W2021985872C555293320 @default.
• W2021985872 hasConceptScore W2021985872C71924100 @default.
• W2021985872 hasIssue "7" @default.
• W2021985872 hasLocation W20219858721 @default.
• W2021985872 hasLocation W20219858722 @default.
• W2021985872 hasOpenAccess W2021985872 @default.
• W2021985872 hasPrimaryLocation W20219858721 @default.
• W2021985872 hasRelatedWork W1592119877 @default.
• W2021985872 hasRelatedWork W1957106181 @default.
• W2021985872 hasRelatedWork W1965875712 @default.
• W2021985872 hasRelatedWork W1998398727 @default.
• W2021985872 hasRelatedWork W2025731911 @default.
• W2021985872 hasRelatedWork W2109567385 @default.
• W2021985872 hasRelatedWork W2124135959 @default.
• W2021985872 hasRelatedWork W2527047102 @default.
• W2021985872 hasRelatedWork W4242900151 @default.

• next