Matches in SemOpenAlex for { <https://semopenalex.org/work/W2022005705> ?p ?o ?g. }
- W2022005705 endingPage "41" @default.
- W2022005705 startingPage "35" @default.
- W2022005705 abstract "Bombesin and its mammalian equivalent, gastrin-releasing peptide (GRP), stimulate cell proliferation and are involved in the pathogenesis of several types of human cancer. Bombesin-like peptides also display neuroendocrine activities and regulate neural function. In the present study, we evaluated the effects of the bombesin/GRP receptor antagonist (d-Tpi6, Leu13 psi[CH2NH]-Leu14) bombesin-(6–14) (RC-3095), experimental antitumor drug, on memory in rats. Adult female Wistar rats were treated with an intraperitoneal injection of RC-3095 (0.2, 1.0 or 5.0 mg/kg) 30 min before training in either inhibitory avoidance or novel object recognition tasks. Retention test trials were carried out 1.5 (short-term memory) or 24 h (long-term memory) after training. RC-3095 at the doses of 0.2 or 1.0 mg/kg, but not at the dose of 5.0 mg/kg, impaired both short- and long-term inhibitory avoidance retention, but did not affect recognition memory. The memory-impairing effect of RC-3095 could not be attributed to alterations in sensorimotor functions. The results show that the antitumor drug/GRP antagonist RC-3095 impairs formation of aversive memory." @default.
- W2022005705 created "2016-06-24" @default.
- W2022005705 creator A5008599563 @default.
- W2022005705 creator A5034971594 @default.
- W2022005705 creator A5037075541 @default.
- W2022005705 creator A5044040883 @default.
- W2022005705 creator A5056454984 @default.
- W2022005705 creator A5088021168 @default.
- W2022005705 date "2004-02-13" @default.
- W2022005705 modified "2023-10-11" @default.
- W2022005705 title "RC-3095, a bombesin/gastrin-releasing peptide receptor antagonist, impairs aversive but not recognition memory in rats" @default.
- W2022005705 cites W1481984979 @default.
- W2022005705 cites W1515228700 @default.
- W2022005705 cites W1562273048 @default.
- W2022005705 cites W1596780846 @default.
- W2022005705 cites W1876061808 @default.
- W2022005705 cites W1963940318 @default.
- W2022005705 cites W1965591468 @default.
- W2022005705 cites W1973868943 @default.
- W2022005705 cites W1974768040 @default.
- W2022005705 cites W1975594456 @default.
- W2022005705 cites W1977818538 @default.
- W2022005705 cites W1980024704 @default.
- W2022005705 cites W1986350377 @default.
- W2022005705 cites W1989667081 @default.
- W2022005705 cites W2008814271 @default.
- W2022005705 cites W2010831415 @default.
- W2022005705 cites W2011560428 @default.
- W2022005705 cites W2014401930 @default.
- W2022005705 cites W2015939711 @default.
- W2022005705 cites W2020607517 @default.
- W2022005705 cites W2026198362 @default.
- W2022005705 cites W2030136627 @default.
- W2022005705 cites W2032525879 @default.
- W2022005705 cites W2036099498 @default.
- W2022005705 cites W2040367138 @default.
- W2022005705 cites W2043245730 @default.
- W2022005705 cites W2049997217 @default.
- W2022005705 cites W2052792745 @default.
- W2022005705 cites W2054425455 @default.
- W2022005705 cites W2056266528 @default.
- W2022005705 cites W2065246100 @default.
- W2022005705 cites W2070341004 @default.
- W2022005705 cites W2073909760 @default.
- W2022005705 cites W2075373947 @default.
- W2022005705 cites W2076535105 @default.
- W2022005705 cites W2097856415 @default.
- W2022005705 cites W2104643304 @default.
- W2022005705 cites W2120329938 @default.
- W2022005705 cites W2122684912 @default.
- W2022005705 cites W2166137662 @default.
- W2022005705 cites W2295527830 @default.
- W2022005705 doi "https://doi.org/10.1016/j.ejphar.2003.12.011" @default.
- W2022005705 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/14751406" @default.
- W2022005705 hasPublicationYear "2004" @default.
- W2022005705 type Work @default.
- W2022005705 sameAs 2022005705 @default.
- W2022005705 citedByCount "39" @default.
- W2022005705 countsByYear W20220057052012 @default.
- W2022005705 countsByYear W20220057052014 @default.
- W2022005705 countsByYear W20220057052016 @default.
- W2022005705 countsByYear W20220057052017 @default.
- W2022005705 countsByYear W20220057052018 @default.
- W2022005705 countsByYear W20220057052020 @default.
- W2022005705 crossrefType "journal-article" @default.
- W2022005705 hasAuthorship W2022005705A5008599563 @default.
- W2022005705 hasAuthorship W2022005705A5034971594 @default.
- W2022005705 hasAuthorship W2022005705A5037075541 @default.
- W2022005705 hasAuthorship W2022005705A5044040883 @default.
- W2022005705 hasAuthorship W2022005705A5056454984 @default.
- W2022005705 hasAuthorship W2022005705A5088021168 @default.
- W2022005705 hasBestOaLocation W20220057051 @default.
- W2022005705 hasConcept C118303440 @default.
- W2022005705 hasConcept C126322002 @default.
- W2022005705 hasConcept C134018914 @default.
- W2022005705 hasConcept C15744967 @default.
- W2022005705 hasConcept C170493617 @default.
- W2022005705 hasConcept C185592680 @default.
- W2022005705 hasConcept C2776885963 @default.
- W2022005705 hasConcept C2776998989 @default.
- W2022005705 hasConcept C2778122271 @default.
- W2022005705 hasConcept C2778448772 @default.
- W2022005705 hasConcept C71924100 @default.
- W2022005705 hasConcept C98274493 @default.
- W2022005705 hasConceptScore W2022005705C118303440 @default.
- W2022005705 hasConceptScore W2022005705C126322002 @default.
- W2022005705 hasConceptScore W2022005705C134018914 @default.
- W2022005705 hasConceptScore W2022005705C15744967 @default.
- W2022005705 hasConceptScore W2022005705C170493617 @default.
- W2022005705 hasConceptScore W2022005705C185592680 @default.
- W2022005705 hasConceptScore W2022005705C2776885963 @default.
- W2022005705 hasConceptScore W2022005705C2776998989 @default.
- W2022005705 hasConceptScore W2022005705C2778122271 @default.
- W2022005705 hasConceptScore W2022005705C2778448772 @default.
- W2022005705 hasConceptScore W2022005705C71924100 @default.
- W2022005705 hasConceptScore W2022005705C98274493 @default.
- W2022005705 hasIssue "1" @default.
- W2022005705 hasLocation W20220057051 @default.