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- W2022021027 abstract "When small doses of allogeneic spleen cells are injected into rabbits or mice made tolerant to either human or bovine serum albumin, about half the treated animals will escape from tolerance. The effective doses in rabbits are 2 x 106 to 5 x 106 cells per animal and in mice 104 to 106 cells per animal. Larger doses, around 25 x 106 cells in rabbits, are ineffective. It is suggested that by transferring sufficiently small doses of allogeneic cells the threshold of the recipient's rejection mechanism can be circumvented." @default.
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- W2022021027 date "1973-05-01" @default.
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- W2022021027 title "Abrogation of immune tolerance to protein antigens in tolerant rabbits and mice by transfer of allogeneic spleen cells in small doses" @default.
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- W2022021027 doi "https://doi.org/10.1002/eji.1830030513" @default.
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